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Yale University
School of Medicine
333 Cedar Street
New Haven, CT 06510

Public information: 203.785.5824

Yale University School of Medicine
Electron Microscopy in the Molecular Era: A World Inside the World You See

Friday November 10, 2006 1:30 - 3:30 PM

The Anlyan Center Auditorium

300 Cedar Street, New Haven

Small molecules can serve as valuable research tools and aid in the discovery of new therapeutics. They can mimic or disrupt cellular interactions, enzymatic activities and signaling pathways critical in development and disease. The Yale Chemical Genomics Screening Facility identifies small molecules with a desired biological activity by testing thousands of small molecule compounds individually in high-throughput biological assays. Hear Yale scientists describe their search for small molecules that regulate the activity of RNA riboswitches, facilitate neural repair, stop the cellular aging process and alter zebrafish development.

		Opening Remarks Robert J. Alpern, M.D. Dean, Yale School of Medicine; Ensign Professor of Medicine
		Small Molecule Screening in Academia Craig M. Crews, Ph.D. Associate Professor of Molecular, Cellular and Developmental Biology; Pharmacology; and Chemistry
		Finding Active Small Molecules Through Yale’s Chemical Genomics Center Janie Merkel, Ph.D. Director, Chemical Genomics Screening Facility
		High-Throughput Screening to Discover Small Molecule Promoters of Neurite Outgrowth Erik C. Gunther, Ph.D. Associate Research Scientist in Neurology
		Combining Chemical and Mendelian Genetics to Study Zebrafish Development Scott A. Holley, Ph.D. Assistant Professor of Molecular, Cellular and Developmental Biology
		High-Throughput Screening for the Discovery of Riboswitch-Targeting Antibacterial Compounds Kenneth F. Blount, Ph.D. Associate Research Scientist in Molecular, Cellular and Developmental Biology
		Cell-based Screening for Inhibitors of Cellular Senescence Daniel C. DiMaio, M.D., Ph.D. Waldemar Von Zedtwitz Professor of Genetics Professor of Therapeutic Radiology

REFRESHMENTS WILL BE SERVED

SPONSORED BY
Office of the Dean, Yale School of Medicine

About The Dean's Workshops

The Dean's Workshops series brings together physicians and scientists from across the School of Medicine, the Yale medical center and Yale University to address topics of critical importance in advancing biomedical research and patient care. The workshops will serve as a forum for new ideas and collaborations across disciplines.

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