
Yale University School of Medicine
Electron Microscopy in the Molecular Era: A World Inside the World You See
Friday, October 17, 2008, 1:30–3:30 pm
The Anlyan Center Auditorium
300 Cedar Street, New Haven
The complete sequencing of the human genome, and many other genomes has given rise to the field of proteomics, which seeks to extend genomic discoveries to the level of the corresponding proteins. New technologies are being rapidly developed to quantify the concentrations of individual proteins, along with their many post-translational modifications in vivo, and also to identify differentially expressed biomarker proteins that may enable the earlier diagnosis, improved prognosis, and more “personalized” treatment of disease. This workshop will highlight the impact of proteomics on biomedical research covering a range of disease applications from hypertension to drug addiction and to the effect of bioterrorism and infectious disease agents. The workshop will also describe the state-ofthe- art proteomics technologies available at Yale’s W.M. Keck Foundation Biotechnology Resource Laboratory and its associated centers.
Website: http://keck.med.yale.edu/
Tours of the Keck Proteomics facilities located at 300 George Street will be available immediately following the workshop. Sign-up sheets will be available in the lobby.

Opening Remarks |
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Carolyn W. Slayman, Ph.D. Deputy Dean for Academic and Scientific Affairs Sterling Professor of Genetics Professor of Cellular and Molecular Physiology |
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Presentations |
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Proteomics at the Keck Laboratory
Erol E. Gulcicek, Ph.D. Deputy Director, Keck Laboratory, Proteomics Associate Research Scientist in Molecular Biophysics and Biochemistry
Christopher M. Colangelo, Ph.D.
Director, Keck Protein Profiling Resource Associate Research Scientist in Molecular Biophysics and Biochemistry
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New Mechanisms Controlling Cell Volume, Neuronal Excitability, and Blood Pressure Revealed via Quantitative Proteomics
Jesse Rinehart, Ph.D. Associate Research Scientist, Department of Genetics |
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Approaches and Challenges in Neuroproteomics
Angus C. Nairn, Ph.D.
Charles B.G. Murphy Professor of Psychiatry and Professor of Pharmacology |
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Knowledge of the Influenza Virion Proteome Provides Insight into Virus-Host Interactions
Megan L. Shaw, Ph.D.
Assistant Professor Department of Microbiology, Mount Sinai School of Medicine |
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Closing Remarks |
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Erol E. Gulcicek, Ph.D. |
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REFRESHMENTS WILL BE SERVED
SPONSORED BY
Office of the Dean, Yale School of Medicine

About The Dean's Workshops
The Dean's Workshops series brings together physicians and scientists from across the School of Medicine,
the Yale medical center and Yale University to address topics of critical importance in advancing biomedical research and patient care. The workshops will serve as a forum for new ideas and collaborations across
disciplines.




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