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Why does the Yale University School of Medicine have a thesis requirement? Every M.D. student has asked that question at least once, when the facts wouldn’t fit or the conclusions seemed too weak. But every M.D. who has graduated from Yale since 1839 has completed a thesis based on original research. And most have understood, in the end, why the thesis is central to the Yale System.

All physicians are scientists. Medicine requires lifelong study, because every field is constantly changing and every individual is different. By engaging in focused, advanced research–whether it’s actually in a laboratory or clinical science or in ethics, ethnography, or the history of medicine–students participate in the scientific process of investigation, attentive observation, interpretation of data, and critical evaluation of literature. These tools are as fundamental for a doctor making a diagnosis as for an investigator advancing the frontier of medicine.

More than 90 percent of Yale students begin their research by the end of their first year. All receive summer stipends to support their research. To pursue their investigations, some choose to travel to other institutions or to field sites, and many spend an extra year at Yale, without charge.

The Office of Student Research, directed by John Forrest, M.D., helps students identify faculty working in their field of interest and locate grants and fellowships. OSR itself provides about $735,000 in student research support annually, funding fellowships of one month to one year.

Students work closely with individual faculty members in laboratories, clinics, or other settings. At the end of the year, students who have completed their theses present their research findings to faculty, distinguished visiting scientists, and their fellow students at the annual Student Research Day. As part of a laboratory’s work, student findings are often published in peer-reviewed scientific journals. Research for the thesis frequently opens unanticipated career paths and sets the direction for lifelong pursuits.

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A sampler of recent M.D. theses



Every M.D. graduating from Yale since 1839 has completed a thesis that represents a substantial body of original research. A few recent titles:



Analysis of Structure and Function in the Na-K-Cl Cotransporter*



Carotid Body Chemoreceptors: Mechanisms of Neurotransmitter Release



Effects of Mental Stress on Regional Myocardial Blood Flow in Patients with Coronary Artery Disease



Film Documentary as Ethnography: Tempering Medical Ethics with Patient Stories*



Fractures in Young Children: Determining Patterns of Abuse



Managing Childhood Seizures with Antiepileptic Drugs in the Emergency Department



Medicaid Managed Care in Connecticut: A Look at the Yale Preferred Health Plan



Medicine and Motherhood: A Study of Women from the Yale School of Medicine



A Novel Method of Gene Therapy: Ex Vivo Genetic Engineering of Vascular Beds



Phenotypic Expression of Glucorticoid-Remedial Aldosteronism in Large Kindred



Predicting Child Maltreatment Using a Structured Clinical Rating Scale in the Postpartum Period



Properties and Function of Chloride Channels in Human Glial Tumors



The Role of LATS in Mammalian Tumorigenesis, Development, and Cell Cycle Regulation*



The Role of White Yams in the Increased Incidence of Multiple Births in South-western Nigeria*



Shifting Attitudes toward Alcohol’s Effects on the Fetus



Stimulation of Myocardial AMP-activated Protein Kinase by AICAR Increases Cardiac Glucose Uptake and Causes GLUT4 and GLUT1 Translocation in Vivo*



Tissue Engineering Liver: Toward Form and Function



Transient Hypertrophic Cardiomyopathy in Premature Infants



The Use of Computer-Aided Instruction in Learning the Anatomy and Function of the Cranial Nerves



*Awarded the honor of oral presentation at Student Research Day.


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Last modified: Wednesday, 11-Aug-2004 15:00:35 EDT. (PL)