Yale University
Dept. of Psychiatry
300 George Street
New Haven, CT
06511 USA

Tel: 203-785-2117

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Research Endeavors

Molecular Psychiatry NSF Abstracts 2005

Andrade E, Wu T, Colangelo C, Lam T, Berberich M, Stone K, Allen PB, Taylor, JR, Williams KR, Nairn AC, Identification of alterations in synaptic protein composition following chronic cocaine exposure in mice.

Beech, RD, Leffert JL, Rabenstein RL, Picciotto MR, Maintained antidepressant action in BF-1 heterozygous knockout mice.

Bordelon JR, Nairn AC, Greengard P, Muly EC, Differential localization of the D1 receptor and protein phosphatase-1 (PP1) isoforms in prefrontal cortical interneurons.

Brunzell DH, Kochevar C, Neve RL, Picciotto MR, A virally-mediated decrease in nucleus accumbens CREB activity modulates nicotine reimforcement.

Dow AL, Valentine GW, Duman RS, An animal model of refractory depression: a modified learned helplessness paradigm in rats that is robust and long lasting.

D’Sa C, Simen BB, Terwilliger R, Duman RS, Role of the rolipram-sensitive camp-dependent phosphodiesterase type 4A in the mechanism of antidepressant action: insights from constitutive and conditional PDE4A-Null mutant mice.

Dudek NL, Rakhilin SV, Ceglia I, Li C, Nairn AC, Greengard P, Muma NA, Role of RCS protein in Huntington’s disease.

Fujita M, Imaizumi M, D’Sa C, Zoghbi SS, Crescenzo MS, Hong J, Musachio JL, Gee AD, Seidel J, Green MV, Pile VW, Duman RS, Innis RB, In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant treatment.

Girgenti MJ, Ploski J, Duman RS, Newton SS, Electroconvulsive seizure increases vascular density in the hippocampal molecular layer.

Gourley, SL, Kiraly DD, Taylor JR, Prior chronic corticosterone decreases hedonic response to sucrose, motivated behaviors, and MAP kinase signaling I C57/B16 and bdnf heterozygote mice.

Hitchcott, PK, Anderson GM, Lombroso P, Taylor JR, Prefrontal cortical modulation of striatal instrumental habit learning.

Hunsberger JG, Salton SR Duman RS, Custom microarray analysis of exercise regulated genes identifies a novel neurotrophin-induced factor with antidepressant effects.

Kaffman A, David A, Duman RS, The role of neurogenesis in mediating the effects of maternal care on vulnerability to stress.

Kang HJ, Adams DH, Lin A, Simen BS, Rajkowska G, Stockmeier C, Overholser J, Meltzer HY, Jurjus G, Konick L, Newton SS, Duman RS, Gene expression profiling in portmortem prefrontal cortex of major depressive disorder.

Kiraly DD, Olausson P, Matsuzaki H, Nairn AC, Taylor JR, camp mediated changes in AMPA receptor dynamics dependent on EPAC.

Koo, J, Duman RS, Role of interleukin-1? in hippocampal cell proliferation impaired by acute stress.

Krueger DD, Olausson P, Wu T, Williams KR, Taylor JR, Nairn AC, Proteomic analysis of persistent crtico-limbic-striatal neuroadaptations following repeated cocaine exposure in Vervet monkeys.

Lof E, Olausson P, McIntosh M, Taylor JR, Soderpalm B, Involvement of ventral tegmental nicotinic acetylcholine receptors in conditioned reinforcement to ethanol.

Matsuzaki H, Olausson P, Kiraly DD, Taylor JR, Nairn AC, Epac-specific camp analogue induces GluR1 and NR2B degradation via calpain activation in adult hippocampus.

Mineur YS, Somenzi O, Picciotto MR, Antidepressant effects of cytosine, A partial agonist of nicotinic acetylcholine receptors.

Okamoto H, Newton SS, Suda S, Duman RS, Chronic antidepressant treatments up-regulate neurogenic factors in rat hippocampus: role of Wnt/Beta-catenin signaling.

Olausson P, Kiraly DD, Nairn AC, Taylor JR, Activation of hippocampal EPAC disrupts contextual fear conditioning: implications for camp signaling in learning and memory.

Ploski JE, Duman RS, Newton SS, Antidepressant induced gene expression changes in hippocampal subfields- feasibility of laser microssection and RNA amplification.

Quinn JJ, Sanchez H, Taylor JR, Corticotropin-releasing hormone in the ventral tegmental area modulates cocaine-induced locomotor sensitization.

Rabenstein RL, Johnson MB, Caldarone BJ, Picciotto MR, Effect of chronically-administered mecamylamine in two animal models of antidepressant efficacy.

Sanchez H, Quinn JJ, Snyder GL, Taylor JR, Acute and chronic effects of estrogen on phosphorylation of the GluR1 subunit of the AMPA receptor.

Sears RM, Georgescu D, McClung CA, Nestler EJ, DiLeone RJ, Short and long-term mechanisms of MCH action in the nucleus accumbens shell.

Simen BB, Duman CH, Simen AA, Duman RS, TN? signaling in depression and anxiety: behavioral consequences of individual receptor targeting in mice.

Steiner RC, Picciotto MR, Nicotine stimulates extracellular signal-regulated kinase (ERK) phosphorylation in mouse primary cortical cultures.

Suda S, Newton SS, Duman RS, A rodent postpartum model: Behavioral studies and gene profiling using a custom microarray.

Tanis KQ, Newton SS, Duman RS, Identification of CREB-mediated changes in gene transcription following electroconvulsive seizure.

Trinko R, Hommel JD, Marinelli MM, DiLeone RJ, Leptin receptor signaling in the ventral tegmental area.

Tronson NC, Wiseman SL, Olausson P, Taylor JR,Activation of amygdalar PKA enhances reconsolidation of a fear memory.

Uematsu K, Futter M, Higashi H, Maeda H, Nairn AC, Greengard P, Nishi A, DARPP-32-dependent regulation of spinophilin Ser94 phosphorylation in neostriatal neurons of direct and indirect pathways.

Valentine GW, Banasr M, Li X, Heninger GR, Duman RS, Chronic unpredictable stress decreases cell proliferation in the prefrontal cortex of the rat.

Warner JL, Duman RS, Vascular endothelial growth factor mediates antidepressant-induced neurogenesis.

Wiseman SL, Lynch WJ, Olausson P, Taylor JR, Sex differences in review-related learning after repeated nicotine exposure during adolescence.

Last modified: September 27, 2005