![]() Yale University Dept. of Psychiatry 300 George Street New Haven, CT 06511 USA Tel: 203-785-2117 ![]() |
Department of Psychiatry Faculty
Education1987, B.S./M.S., Molecular Biochemistry and Biophysics, Yale University Research InterestOur research group is interested understanding the relationship between "behavioral" addictions and drug addictions. In particular, we are interested in the etiology and treatment of pathological gambling and the relationship between pathological gambling and drug use disorders. Our research group uses a variety of investigative approaches (fMRI neuroimaging, molecular genetic, clinical treatment trials, and statistical analysis of databases) to investigate these areas. Our group has taken a variety of approaches to investigate the neurobiology and treatment of pathological gambling. First, we are using functional magnetic resonance imaging to investigate the neural activities underlying gambling urges, and how individuals with pathological gambling differ from those without in behavioral and neural responses to gambling cues. A second line of investigation involves the identification of genetic factors related to the development of pathological gambling. A third line of investigation involves psychopharmacological trials in the treatment of individuals with pathological gambling. We are participating in the first multicenter trial testing the efficacy and tolerability of drug therapy for pathological gambling, as well as conducting pharmacotherapy trials solely within our center. A fourth area of interest involves the examination of gender differences of males and females with pathological gambling. Publications of NotePotenza, M.N. (2007). To do or not to do? The complexities of addiction, motivation, self-control and impulsivity. American Journal of Psychiatry 164, 4-6. Potenza, M.N. (2006). Should addictive disorders include non-substance-related conditions? Addiction, 101(s1), 142-151. Potenza, M.N. Xian H, Shah K.R., Scherrer J.F., & Eisen S.A. (2005). Shared genetic contributions to pathological gambling and major depression in men. Archives of General Psychiatry 62,1015-1021. Potenza, M.N. Steinberg, M.A., Skudlarski, P., Fulbright, R.K., Lacadie, C.M., Wilber, M.K., Rounsaville B.J., Gore J.C., & Wexler B.E. (2003). Gambling urges in pathological gamblers: An fMRI study. Archives of General Psychiatry, 60, 828-836. Potenza, M.N. Leung, H.C., Blumberg, H.P., Peterson, B.S., Fulbright, R.K., Lacadie, C.M., Skudlarski, P., & Gore, J.C. (2003). An fMRI Stroop study of ventromedial prefrontal cortical function in pathological gamblers. American Journal of Psychiatry,160, 1990-1994.
Last modified:
August 7, 2007
|