Pharmacology Events
March 2010

Thursday 11th

Eric Weiss, PhD SEMINAR: "Coordinated control of transcription and translation by an Ndr/LATS signaling pathway"

February 2010

Thursday 18th	Klaus Hahn, PhD SEMINAR: "Peeking and poking at proteins in living cells with light: photomanipulation of Rho pathways"
Tuesday 16th	Charles Zuker, Ph.D. SEMINAR: "From the tongue to the brain: the biology of mammalian taste"

December 2009

Thursday 3rd

Doron Greenbaum, Ph.D. SEMINAR: "Deciphering a host-calpain mediated pathway hijacked by malaria and toxoplasma parasites"

November 2009

Monday 23rd	Dr. Sachdev Sidhu SEMINAR: "Deciphering and Modulating Cellular Signaling with Combinatorial Biology"
Thursday 19th	Reuben J. Shaw, Ph.D. SEMINAR: "The LKB1/AMPK tumor suppressor pathway controls cell growth and metabolism"
Monday 16th	Wei Jia, Ph.D. SEMINAR: "Metabolomics in evaluation of cancer and metabolic disorders"
Thursday 12th	Joan Brugge, Ph.D. SEMINAR [CANCELLED]: "Morphogenesis and Oncogenesis in 3D Culture Models of Epithelial Cells"
Tuesday 3rd	Eric A.C. Weimer, Ph.D. SEMINAR: "The Vault Complex: still an enigmatic ribonucleoprotein particle!"

October 2009

Thursday 29th	Rachelle Gaudet, Ph.D. SEMINAR: "Heat and Spice: Setting the Sensitivity of TRP Channels"
Thursday 22nd	RETREAT: Announcing... The Department of Pharmacology Autumn Retreat...
Thursday 15th	Olga Boudker, Ph.D. SEMINAR: "Alternating access mechanism of glutamate transporters"
Thursday 1st	Anthony Wynshaw-Boris, MD, PhD SEMINAR: "Dishevelled: In vivo analysis of a functionally redundant gene family"

August 2009

Monday 17th	Dr. Emmanuel Van Obberghen SEMINAR: "Insulin action in diabetes and its complications."
Friday 14th	Dr. Ellen Van Obberghen-Schilling SEMINAR: "Oncofetal fibronectin in the tumor setting: mechanisms of assembly & role in endothelial cell plasticity."

July 2009

Monday 6th

Professor Naomi Chayen SEMINAR: "Protein Crystallization: Magic versus Logic"

May 2009

Thursday 7th

Wolfgang Peti, Ph.D. SEMINAR: "Structural Basis on Protein Phosphatase 1 Regulation"

April 2009

Thursday 30th

Jin Zhang, Ph.D. SEMINAR: "Visualization of Kinase Activities and Second Messenger Dynamics in Living Cells"

March 2009

Thursday 19th	Shimon Schuldiner, Ph.D. SEMINAR: "Evolution and mechanism of ion-coupled transporters: EmrE as an experimental paradigm"
Wednesday 11th	Vinzenz Unger SEMINAR: "From Copper Transport to Membrane Remodeling - CryoEM a Versatile Tool to Address Challenges in Membrane Biology"
Monday 9th	Gail Mandel, Ph.D. SEMINAR: "The road to neuronal differentiation: REST stops along the way"
Thursday 5th	Phillip Furman, Ph.D. SEMINAR: "The road to a liver targeting nucleotide prodrug active against HCV"

February 2009

Thursday 26th	Eitan Bibi, Ph.D. SEMINAR: "Membrane targeting of ribosomes, mRNAs, and the SRP-receptor in E. Coli"
Thursday 19th	Raymond Stevens, Ph.D. SEMINAR: "Structure-Function of the G-protein Coupled Receptor Family"

January 2009

Thursday 29th

Elijah Paintsil, M.D. SEMINAR: "From Clinic to Bench to Clinic: D4T derivative, 4'-ethynylD4T"

December 2008

Thursday 11th	Björn Schroeder, Ph.D. SEMINAR: "TMEM16A: Expression cloning of a new family of calcium activated chloride channels"
Thursday 4th	Thomas Kirchhausen, Ph.D. SEMINAR: "How Clathrin Coated Vesicles Form"

November 2008

Friday 7th

RETREAT: Annual Pharmacology Retreat Information...

October 2008

Thursday 30th	Gökhan Hotamisligil, M.D., Ph.D. SEMINAR: "Nutrient and Pathogen Response System and Metabolic Control"
Thursday 16th	Mark Distefano, Ph.D. SEMINAR: "Chemical Biology of Protein Prenylation"
Tuesday 7th	Lucy Forrest, Ph.D. SEMINAR: "Molecular mechanisms of sodium-coupled neurotransmitter transport: insights from computational studies"

September 2008

Thursday 18th

Arthur Salomon, Ph.D. SEMINAR: "Quantitative Phosphoproteomic Dissection of Signaling Pathways Applied to T Cell and Mast Cell Signaling"

July 2008

Thursday 24th

Dr. Nir Ben-Tal SEMINAR: "Model structure of human copper transporter 1, a Transmembrane protein of novel fold, offers insight into its transport mechanism"

May 2008

Thursday 22nd	Hans Rollema, Ph.D. SEMINAR: [Updated] "Rationale and desgin of α4ß2 nAChR partial agonists for smoking cessation: discovery and development of varenicline"
Friday 9th	Roel Nusse, Ph.D. SEMINAR: "Wnt signaling and stem cell control"
Thursday 1st	Patricia Keely, Ph.D. SEMINAR: "Understanding mechano-signaling events that underly breast cell response to dense matrices"

April 2008

Thursday 24th	Deborah K. Morrison, Ph.D. SEMINAR: [Updated] "Regulation of Raf Kinase Signaling"
Thursday 17th	Matthew Freeman, Ph.D. SEMINAR: [Updated] "Intramembrane proteolysis by rhomboids"
Thursday 10th	Michael Yaffe, M.D., Ph.D. SEMINAR: [Updated] "Cell cycle control by protein kinases and phosphopeptide-binding domains: a collusion of stress signals, mitotic kinases and checkpoints"
Tuesday 8th	Colin W. Taylor, Ph.D. SEMINAR: [Updated] "The private lives of IP3 receptors"
Thursday 3rd	V.P. Eswarakumar, Ph.D. SEMINAR: [Updated] "FGF Receptor Signaling in Craniofacial Development and Mineral Homeostatis"

March 2008

Thursday 27th	Michael Eck, M.D., Ph.D. SEMINAR: [Updated] "Tyrosine kinase regulation and dysregulation: Insights from structure and mechanistsic studies of FAK and EGFDR"
Thursday 20th	Gabriel Corfas, Ph.D. SEMINAR: "erbB receptor signaling in the nervous system: roles in development and disease"
Thursday 13th	Peter Kwong, Ph.D. SEMINAR: "HIV-1 gp120 - vaccine and therapeutic target"

February 2008

Monday 25th	David Julius, Ph.D. SEMINAR: [Updated] "From Peppers to Peppermints: Natural Products as Probes of the Pain Pathway"
Thursday 7th	Patricia Keely Ph.D. SEMINAR: [Cancelled] "Understanding mechano-signaling events that underly breast cell response to dense matrices"

January 2008

Thursday 24th

Barry Honig SEMINAR: [Updated] "Relating Cellular to Molecular Specificity"

December 2007

Thursday 13th	Roger Nicholl, M.D. SEMINAR: "Glutamate receptor trafficking and synaptic plasticity"
Thursday 6th	Norbert Perrimon, Ph.D. SEMINAR: "A comprehensive approach to Drosophilia muscle growth"

November 2007

Thursday 29th	Chris Dealwis, Ph.D. SEMINAR: [Updated] "Structural studies of the cancer target ribonucleotide reductase and Alzheimer's causing Aβ"
Thursday 15th	Stephen Traynelis, Ph.D. SEMINAR: [Updated] "Control of NMDA receptor function by extracellular Zn2+"
Thursday 8th	Stephen Blackow, M.D., Ph.D. Seminar: "Mechanistic Insights into Normal and Pathogenic Notch Signaling"

October 2007

Thursday 18th	Anthony Auerbach, Ph.D. SEMINAR: ""Acetylcholine receptor gating: whole lotta shakin' goin' on"
Thursday 11th	Matthew Rasband, Ph.D. SEMINAR: "Instrinsic and Extrinsic Mechanisms of Ion Channel Clustering in Axons"

September 2007

Friday 21st	RETREAT: [Updated] "The Department of Pharmacology Autumn Retreat"
Thursday 20th	Peter Davies, Ph.D. SEMINAR: "Strategies for inhibiting calpains-the calcium-dependent cysteine proteases of the cytoplasm"

August 2007

Friday 3rd

Oliver Griesbeck, Ph.D. SEMINAR: "Designing And Imaging Green Fluorescent Protein Biosensors"

July 2007

Wednesday 25th	John E. Ladbury, Ph.D. SEMINAR: "If All Tyrosine Kinase-Mediated Pathways Lead to MAPK - What Controls the Traffic?"
Tuesday 17th	Makoto Kuro-o, M.D., Ph.D. SEMINAR: "The Klotho gene family: regulators of FGF and metabolism"

May 2007

Thursday 31st	Claudio Grosman, Ph.D. SEMINAR: "Acid-base chemistry and the structure and electrostatics of the nictonic-receptor"
Tuesday 29th	Alain Marty, Ph.D. SEMINAR: "GABA-induced Excitation in the Cerebellum"

April 2007

Monday 23rd	Piotr Sliz, Ph.D. SEMINAR: "Crystal structure of the peptidoglycan glycosyltransferase from class A PBP: insight into bacterial cell wall synthesis"
Monday 23rd	James Murphy, Hui Qin, Vivi Ko, Todd Hoopes, Brett Bessac, Barbara Ehrlich, James Howe SYMPOSIUM: "Neuropharmacology Training Grant Minisymposium"
Thursday 19th	David Rodgers, Ph.D. SEMINAR: "Fuzzy Substrate Specificity in Neuropeptidases"
Thursday 12th	Michael Caterina, M.D.,Ph.D. SEMINAR: "Transient Receptor Potential Ion Channels and Temperature Sensation"

March 2007

Wednesday 21st

Naomi Chayen, Ph.D. SEMINAR: "The Joys and Challenges of Protein Crystallization"

February 2007

Thursday 22nd	Gali Prag, Ph.D. SEMINAR: "Structural Mechanisms for Recognition and Trafficking of Ubiquitylated Proteins"
Thursday 15th	David Clapham, M.D.,Ph.D. SEMINAR: "New Ion Channels"
Thursday 8th	Mathew Bogyo, Ph.D. SEMINAR: "Small molecule probes of protease function: applications from cancer to malaria"

January 2007

Wednesday 10th

Sergei Nedospasov, Ph.D. SEMINAR: "“Defining physiological thresholds for Tumor Necrosis Factor beneficial and deleterious functions using engineered mice”

November 2006

Thursday 30th	Tomas Mustelin, Ph.D. SEMINAR: “Protein Tyrosine Phosphatases: From Genome to Human Disease”
Thursday 9th	Jun Liu, Ph.D. SEMINAR: “Exploring the Existing Pharmacological Space for Novel Probes in Chemical Biology”
Thursday 2nd	Bryan Hains, Ph.D. SEMINAR: “Nav1.3 and the pathological sensory neuraxis after spinal cord injury”

October 2006

Thursday 19th	Hanns Ulrich Zeilhofer, M.D. SEMINAR: “Molecular Dissection of GABAergic and Glycinergic Pain Control”
Thursday 12th	Gilad Barnea, Ph.D. SEMINAR: “The Neuronal Circuitry Underlying Olfactory Perception”
Thursday 5th	Howard Gu, Ph.D. SEMINAR: “Abolished cocaine reward in knock-in mice with cocaine-resistant dopamine transporter”

September 2006

Thursday 28th	Mark Ginsberg, M.D. SEMINAR: “Integrin Signaling in Cancer and Inflammation”
Thursday 21st	Loren W. Runnels, Ph.D. SEMINAR: "TRPM7, an Ion Channel on the Cutting Ege of Cell Motility"
Friday 8th	RETREAT: "Department of Pharmacology Retreat to be held at the Heritage Resort & Conference Center"

June 2006

Thursday 22nd

Wenfeng Miao, M.D.,Ph.D. SEMINAR: “The Endocannabinoid System and its Implications in the Management of Obesity, Metabolic and Cardiovascular Disease”

May 2006

Thursday 25th	Lawrence Shapiro, Ph.D. SEMINAR: “Sticking together as a family: Molecular mechanisms of cadherin-mediated cell adhesion”
Thursday 18th	Alex Toker, Ph.D. SEMINAR: “The Akt/PKB Signaling Pathway in Cancer Cell Signaling and Biology”
Tuesday 9th	Marc Tessier-Lavigne, Ph.D. SEMINAR: “Common mechanisms of axon guidance and vascular patterning”
Thursday 4th	Leslie V. Parise, Ph.D. SEMINAR: “CIB1, A Novel Regulator of Integrin Activation and Cell”

April 2006

Thursday 20th

Dean Sheppard, Ph.D. SEMINAR: “Teaching an ancient adhesion receptor family new tricks: Lessons from integrin subunit knockout mice”

March 2006

Friday 3rd	Joseph W. Ramos, Ph.D. SEMINAR: “Erk MAP kinase binding and activation of the kinase Rsk2 is enhanced by a scaffold protein called PEA-15 in lymphocytes and astrocytes”
Thursday 2nd	Ilya Bezprozvanny, Ph.D. SEMINAR: “Neuronal calcium signaling and Huntington’s disease”

January 2006

Friday 13th

Jan-Åke Gustafsson, M.D, Ph.D. SEMINAR: “A new look at estrogen signaling”

October 2005

Thursday 27th	Craig Crews, Ph.D. SEMINAR: “Chemical Genetics: Probing Cell Biology with Small Molecules”
Thursday 6th	Guy Salvesen, Ph.D. SEMINAR: “Molecular Mechanisms of the Death Pathway”

September 2005

Thursday 29th	Morris Birnbaum, M.D., Ph.D. SEMINAR: “The regulation of lipid and carbohydrate metabolism by Akt/PKB”
Thursday 15th	David N. Garboczi, Ph.D. SEMINAR: “The Structural Biology of Essential Proteins of the Surface of the Malaria Parasite”
Thursday 8th	Maureen Barr, Ph.D. SEMINAR: “Sensation and human cystic kidney disease models in C. elegans”

August 2005

Wednesday 10th

Prof. Dr. Ulf R. Rapp SEMINAR: “Novel Regulators of Raf Kinase Signaling”

July 2005

Friday 15th

Sima Lev, Ph.D. SEMINAR: “Lipid homeostasis and Golgi secretory function; the role of the peripheral Golgi protein Nir2”

June 2005

Tuesday 14th	Kenneth Sang-Ho Kwon, Ph.D. SEMINAR: “Movin’ on Up: How the large conductance calcium-activated K channel traffics to the proper cell surface”
Wednesday 8th	Kevin P. Campbell SEMINAR: “Maintenance of Cell Membrane Integrity and the Pathogenesis of Muscular Dystrophy"

May 2005

Wednesday 18th	Jeroen den Hertog, Ph.D. SEMINAR: “Regulation of Receptor Protein-Tyrosine Phosphatases”
Friday 13th	Stevan Hubbard, Ph.D. SEMINAR: “Structural Basis for Protein Recruitment to the Insulin Receptor”
Thursday 12th	Robert Edwards, M.D. SEMINAR: “The Neurotransmitter Cycle: Different Mechanisms for Different Signals”

April 2005

Thursday 21st	Titus Boggon, Ph.D. SEMINAR: “Janus Kinase Structural Studies”
Monday 18th	Nathan Nelson, Ph.D. SEMINAR: “Effect of Zinc on GABA Transporters-a Novel Link Between Excitatory and Inhibitory Neurotransmitters”
Thursday 7th	Ronald Duman SEMINAR: "Neurotriphic and Neurogenic Actions of Antidepressant Treatment"

March 2005

Thursday 24th	Ulrich Mueller, Ph.D. SEMINAR: “Mechanism that Regulate the Development and Function of Mechanosensory Hair Cells”
Thursday 17th	Hui Zheng, Ph.D. SEMINAR: “Amyloid Precursor Proteins and Presenilins: Physiological Functions and Pathogenic Mechanisms in Alzheimer’s Disease”
Thursday 10th	Paul M. Coates, Ph.D. SEMINAR: “The NIH Investment in Dietary Supplement Research”

February 2005

Thursday 24th	Zhizhuang Joe Zhao, Ph.D. SEMINAR: "Regulation and Function of Tyrosine Phosphatases"
Monday 14th	Rodolfo R. Llinas, M.D., Ph.D. SEMINAR: "Of Neurons, Circuits and Cognition"

January 2005

Tuesday 18th	Erling Donnelly THESIS DEFENSE: Erling Donnelly
Thursday 6th	Dagny Ulrich THESIS DEFENSE: Dagny Ulrich

December 2004

Tuesday 14th	Department of Pharmacology Holiday Party
Thursday 9th	Agnes Vignery, Ph.D. SEMINAR: “Macrophage fusion: molecular mechanisms”

November 2004

Friday 19th	Symposium to Honor Dr. Tommy Cheng
Thursday 11th	Gil Mor, Ph.D. SEMINAR: “Apoptosis and cancer: basic mechanisms and therapeutic applications”

June 2004

Monday 21st

Peter Lonai, Ph.D. SEMINAR: “Laminin: architectural element or signaling molecule”