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The Yale Pediatric Thyroid Center

Research

Expanding our knowledge of the treatment and causes of pediatric thyroid disease is a major goal of the Yale Pediatrics Thyroid Center. Important contributions of our members include the identification of genes that cause thyroid cancer, optimization of treatment of childhood Graves’ disease, and the development of new diagnostic approaches for thyroid disease and thyroid cancer.

Select publications by our members

Dinauer CA, Breuer C, Rivkees SA. Differentiated thyroid cancer in children: diagnosis and management. Curr Opin Oncol. 2008 20(1):59-65.

Rivkees SA, Dinauer C. The Use of 131-Iodine in the Treatment of Graves’ Disease in Children. In Comprehensive Handbook on Iodine: Nutritional, Endocrine and Pathological Aspects 2008.

Roman S, Boudourakis L, Sosa JA. Health services research in endocrine surgery. Curr Opin Oncol. 2008 20(1):47-51.

Deshpande HA, Gettinger SN, Sosa JA. Novel chemotherapy options for advanced thyroid tumors: small molecules offer great hope. Curr Opin Oncol. 2008 20(1):19-24.

Dinauer C, Francis GL. Thyroid cancer in children. Endocrinol Metab Clin North Am. 2007 36(3):779-806.

Rivkees SA. Graves' disease therapy in children: truth and inevitable consequences. J Pediatr Endocrinol Metab. 2007 20(9):953-5.

Rivkees SA, Dinauer C. An optimal treatment for pediatric Graves' disease is radioiodine. J Clin Endocrinol Metab. 2007 92(3):797-800.

Powers PA, Dinauer CA, Tuttle RM, Francis GL. The MACIS score predicts the clinical course of papillary thyroid carcinoma in children and adolescents. J Pediatr Endocrinol Metab. 2004 17(3):339-43.

Sosa JA, Mehta PJ, Wang TS, Yeo HL, Roman SA. Racial disparities in clinical and economic outcomes from thyroidectomy. Ann Surg. 2007 246(6):1083-91.

Krassas G, Rivkees SA, Kiess A. Diseases of the Thyroid in Children and Adolescents. 2006 Karger Press.

Wang TS, Roman SA, Sosa JA. Management of follicular tumors of the thyroid. Minerva Chir. 2007 62(5):373-82.

Yeo H, Roman S, Air M, Maser C, Trapasso T, Kinder B, Sosa JA. Filling a void: thyroid cancer surgery information on the internet. World J Surg. 2007 31(6):1187-93.

Air M, Roman SA, Yeo H, Maser C, Trapasso T, Kinder B, Sosa JA. Outdated and incomplete: a review of thyroid cancer on the World Wide Web. Thyroid. 2007 17(3):259-65.

Fong P, Goyal A, Brennan M, Park J, Moss L, Saltzman WM, Breuer CK. Development of PTH eluting microspheres for the treatment of hypoparathyroidism. J Surg Res. 2007 143(2):195-9.

Rivkees SA. Thyrotrope Hyperplasia. J Pediatr Endocrinol Metab. 2006 19(12):1395.

Rivkees SA. The treatment of Graves' disease in children. J Pediatr Endocrinol Metab. 2006 19(9):1095-111.

Sosa JA, Udelsman R. Total thyroidectomy for differentiated thyroid cancer. J Surg Oncol. 2006 15;94(8):701-7.

Roman S, Lin R, Sosa JA. Prognosis of medullary thyroid carcinoma: demographic, clinical, and pathologic predictors of survival in 1252 cases. Cancer. 2006 1;107(9):2134-42.

Ghofrani M, Sosa JA, Ocal IT, Angeletti C. Fine needle aspiration of poorly differentiated oxyphilic (Hürthle cell) thyroid carcinoma: a case report. Acta Cytol. 2006 50(5):560-2.

Rivkees SA, Cornelius EA. Influence of iodine-131 dose on the outcome of hyperthyroidism in children. Pediatrics. 2003 111(4 Pt 1):745-9.

Powers PA, Dinauer CA, Tuttle RM, Francis GL. Treatment of recurrent papillary thyroid carcinoma in children and adolescents. J Pediatr Endocrinol Metab. 2003 16(7):1033-40.

Powers PA, Dinauer CA, Tuttle RM, Robie DK, McClellan DR, Francis GL. Tumor size and extent of disease at diagnosis predict the response to initial therapy for papillary thyroid carcinoma in children and adolescents. J Pediatr Endocrinol Metab. 2003 6(5):693-702.