Table of ContentsApoptosis and the Fas/Fas Ligand system in the normal Reproductive tissues: Development and Cancer The Cellular Default Condition is Cell Death or Apoptosis Survival signals are delivered by growth factors and hormones that actively stimulates proliferation and suppress default death pathways or apoptosis Tissue Homeostasis PPT Slide An imbalance between these two process can result in either unwanted tissue atrophy or tissue growth PPT Slide PPT Slide The Fas/Fas Ligand System The Fas/FasL System T-cell Activation T-cell Activation: Fas/Fas Ligand Mediated Apoptosis Fas/Fas Ligand Mediated Apoptosis Apoptosis Apoptosis Fas/Fas Ligand System The Fas/FasL System Immune Privilege Immune Privilege The Fas/FasL system in Immune Privilege Organs FasL expression in trophoblast Cells FasL expression in Human Placenta FasL and the Trophoblast Immune Privilege Status FasL and the Trophoblast Immune Privilege Status Evidence against the role of FasL in the immune privilege status of the placenta Fas expression in human placenta Fas expression in human placenta FasL expression in Human Choriocarcinoma cells Immune Privilege status of the Tumor Immune Surveillance Increased tumor incidence in immune-suppressed patients How tumor cells fool the immune system ? Hypothesis Immune privilege status of the tumor Fas Ligand expression in Breast Cancer PPT Slide Immunological Reaction to a Breast Carcinoma Fas Expression in Human Breast Cancer MCF-7 cells Fas/FasL-mediated cytolytic activity Conclusion Fas and Fas Ligand Expression in Reproductive Tissues The Fas/FasL system and Reproductive Tissue Remodeling Mammary Gland Remodeling PPT Slide PPT Slide Conclusion Fas Ligand Expression PPT Slide PPT Slide Tissue Remodeling Tissue Remodeling (2) The Fas/FasL System in the Normal Mammary Gland PPT Slide Regulation of FasL Expression by Sex Hormones The Fas Ligand Promoter PPT Slide Tamoxifen: Dose Response Induction of apoptosis by MCF-7 cells on Fas Positive Jurkat cells PPT Slide SERMS Profile PPT Slide PPT Slide Apoptosis Following Hormone Ablation PPT Slide PPT Slide Hormonal Ablation Dead men may tell no tales, PPT Slide Apoptosis, Macrophages and Immune Protection Apoptosis, Macrophages and Immune protection (2) Apoptosis and Macrophages Apoptosis and Macrophages The Fas/FasL System THE LAB |
Author: Dr. Gil Mor
Email: gil.mor2yale.edu Home Page: http://info.med.yale.edu/obgyn/reproimmuno Best experienced with |
