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NIDA Proteomics Center >  Publications

Publications from the Yale/NIDA Neuroproteomics Center

Patent Applications:

  1. Gulcicek, E., Bruce, C., Shifman, M. and Williams, K. (2005) Use of Fractional Mass for Mass Spectrometric Detection of Phosphopeptides (provisional US patent application).

  2. Pevsner, Paul H., Naftolin, F., Fadiel, A., Gulcicek, E., USPTO patent filed, (2007) Methods for Preparation of Live Body Tissues for Examination (Pub No. US 2007/0110666)

Publications, Manuscripts in Press and Under Minor Revision:

  1. Stone, K.L. and Williams, K.R. (2004) Enzymatic Digestion of Proteins in Gels for Mass Spectrometric Identification and Structural Analysis. In: Current Protocols in Protein Science (Coligan, J.E., Dunn, B.M., Ploegh, H.L., Speicher, D.W. and Wingfield, P.T., Eds.), p. 11.3.1-11.3.10. John Wiley & Sons, New York, (PMID 18429249).

  2. Jin, M., Bateup, H., Padovan, J.C., Greengard, P., Nairn, A.C. and Chait, B.T. (2005) Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry. Anal. Chem 77, 7845-7851. [Proteomics analysis carried out by a member of our External Advisory Board, B. Chait, because at the time we did not have a MS platform capable of carrying out this study. (PMID 16351129).

  3. Lee, S.Y., Voronov, S., Letinic, K., Nairn, A.C., Di Paolo, G. and De Camilli, P. (2005) Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases. J Cell Biol. 168, 789-799. (PMID 15738269).

  4. Shin, H.W., Hayashi, M., Christoforidis, S., Lacas-Gervais, S., Hoepfner, S., Wenk, M.R., Modregger, J., Uttenweiler-Joseph, S., Wilm, M., Nystuen, A., Frankel, W.N., Solimena, M., De Camilli, P. and Zerial, M. (2005) An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway. J Cell Biol. 170, 607-618. (PMID 16103228).

  5. Bruce, C., Shifman, M.A., Miller, P. and Gulcicek, E.E. (2006) Probabilistic enrichment of phosphopeptides by their mass defect. Anal. Chem 78, 4374-4382. (PMID 168084444).

  6. Colangelo, C.M. and Williams, K.R. (2006) Isotope-coded affinity tags for protein quantification. Methods Mol. Biol. 328, 151-158. (PMID 16785647)

  7. Di Paolo, G. and De Camilli, P. (2006) Phosphoinositides in cell regulation and membrane dynamics. Nature 443, 651-657. (PMID 17035995)

  8. Folta-Stogniew, E. (2006) Oligomeric states of proteins determined by size-exclusion chromatography coupled with light scattering, absorbance, and refractive index detectors. In: New and Emerging Proteomics Techniques (Nedelkov, D. and Nelson, R., Eds.), Vol. 328, pp. 97-112. Humana Press, Totowa, NJ, (PMID 16785643)

  9. Gulcicek, E.E., Colangelo, C.M., McMurray, W., Stone, K., Wu, T., Zhao, H., Spratt, H., Kurosky, A., Wu, B. and Williams, K.R. (2006) Proteomics and the Analysis of Proteomic Data: An Overview of Current Protein-Profiling Technologies. In: Current Protocols in Bioinformatics (Baxevanis, A.D., Davison, D.B., Page, R.D.M., Petsko, G.A., Stein, L.D. and Stormo, G.D., Eds.), p. 13.1.1-13.1.13. John Wiley & Sons, Inc, Hoboken, NJ, (PMID 18428746).

  10. Itoh, T. and De Camilli, P. (2006) BAR, F-BAR (EFC) and ENTH/ANTH domains in the regulation of membrane-cytosol interfaces and membrane curvature. Biochim. Biophys. Acta 1761, 897-912. (PMID16938488).

  11. Perera, R.M., Zoncu, R., Lucast, L., De Camilli, P. and Toomre, D. (2006) Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proc. Natl. Acad. Sci. U. S. A 103, 19332-19337. (PMID 17158794).

  12. Wu, B., Abbott, T., Fishman, D., McMurray, W., Mor, G., Stone, K., Ward, D., Williams, K. and Zhao, H. (2006) Ovarian Cancer Classification based on Mass Spectrometry Analysis of Sera. Bioinformatics. 19, 1636-1643.

  13. Wu, T. (2006) Two-Dimensional Difference Gel Electrophoresis. In: New and Emerging Proteomics Techniques (Nedelkov, D. and Nelson, R., Eds.), Vol. 328, Chapter 5, pp. 71-96. Humana Press, Totowa, NJ.

  14. Yu, W., Li, X., Liu, J., Wu, B., Williams, K.R. and Zhao, H. (2006) Multiple peak alignment in sequential data analysis: a scale-space-based approach. IEEE/ACM. Trans. Comput. Biol. Bioinform. 3, 208-219, (PMID 17048459).

  15. Yu, W., Wu, B., Huang, T., Li, X., Williams, K. and Zhao, H. (2006) Statistical methods in proteomics. In: Springer Handbook of Engineering Statistics (Pham, H., Ed.), pp. 623-638

  16. Yu, W., Wu, B., Lin, N., Stone, K., Williams, K. and Zhao, H. (2006) Detecting and aligning peaks in mass spectrometry data with applications to MALDI. Comput. Biol. Chem 30, 27-38. (PMID 16298163).

  17. Yu, W., Wu, B., Liu, J., Li, X., Stone, K., Williams, K.R. and Zhao, H. (2006) MALDI-MS data analysis for disease biomarker discovery. Methods Mol. Biol. 328, 199-216. (PMID: 16785651).

  18. Andrade, E.C., Krueger, D.D. and Nairn, A.C. (2007) Recent advances in neuroproteomics. Curr. Opin. Mol. Ther. 9, 270-281. (PMID: 17608026).

  19. Erdmann, K.S., Mao, Y., McCrea, H.J., Zoncu, R., Lee, S., Paradise, S., Modregger, J., Biemesderfer, D., Toomre, D. and De Camilli, P. (2007) A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway. Dev. Cell 13, 377-390. (PMID: 17765681).

  20. Ferguson, S.M., Brasnjo, G., Hayashi, M., Wölfel, M., Collesi, C., Giovedi, S., Raimondi, A., Gong, L.W., Paradise, S., O'Toole, E., Flavell, R., Cremona, O., Miesenböck, Ryan, T.A., and De Camilli, P. (2007) A Selective Activity Dependent Requriement for Dynamin 1 in Synaptic Vesicle Endocytosis. Science. 316: 570-574. (PMID: 17463283).

  21. Fogel, A.I., Akins, M.R., Krupp, A.J., Stagi, M., Stein, V. and Biederer, T. (2007) SynCAMs organize synapses through heterophilic adhesion. J Neurosci. 27, 12516-12530. (PMID: 18003830).

  22. Krueger, D.D. and Nairn, A.C. (2007) Expression of PKC substrate proteins, GAP-43 and neurogranin, is downregulated by cAMP signaling and alterations in synaptic activity. Eur. J Neurosci. 26, 3043-3053. (PMID: 18005072).

  23. Mani, M., Lee, S.Y., Lucast, L., Cremona, O., Di Paolo, G., De Camilli, P. and Ryan, T.A. (2007) The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron 56, 1004-1018. (PMID: 18093523).

  24. Olausson, P., Jentsch, J.D., Krueger, D.D., Tronson, N.C., Nairn, A.C. and Taylor, J.R. (2007) Orbitofrontal cortex and cognitive-motivational impairments in psychostimulant addiction: evidence from experiments in the non-human primate. Ann. N. Y. Acad. Sci. 1121, 610-638. (PMID: 17698993).

  25. Shifman, M.A., Li, Y., Colangelo, C.M., Stone, K.L., Wu, T.L., Cheung, K.H., Miller, P.L. and Williams, K.R. (2007) YPED: a web-accessible database system for protein expression analysis. J Proteome. Res 6, 4019-4024. (PMID: 17867667).

  26. Stone, K., Bjornson, R.D., Blasko, G., Cofrancesco, R., Carriero, N.J., Colangelo, C., Crawford, J., Crawford, M., DaSilva, N., Deluca, J., Elliott, J., Elliott, M., Flory, P., Folta-Stogniew, E., Gulcicek, E., Kong, Y., Lam, T., Lee, J., Lin, A., LoPresti, M., Mane, S., McMurray, W., Tikhonova, I., Westman, S., Williams, N., Wu, T., Zhao, H. and Williams, K. (2007a) Invited Review. Keck Foundation Biotechnology Resource Laboratory, Yale University, Yale Journal Biology & Medicine 80, 195-211.

  27. Stone, K.L., Crawford, M., McMurray, W., Williams, N. and Williams, K.R. (2007b) Identification of Proteins Based on MS/MS Spectra and Location of Post-translational Modifications. In: Peptide Characterization and Application (Fields, G., Ed.), Vol. 386, pp. 57-77. Humana Press, Totowa, NJ, (PMID: 18604942).

  28. Volpicelli-Daley, L. and De Camilli, .P. (2007) Phosphoinositides' link to neurodegeneration. Nat. Med. 13, 784-786, (PMID: 17618267).

  29. Yu, E.Z., Burba, A.E. and Gerstein, M. (2007a) PARE: a tool for comparing protein abundance and mRNA expression data. BMC. Bioinformatics. 8, 309 - 313. (PMID: 17718915).

  30. Yu, W., Liu, J., Colangelo, C., Gulcicek, E. and Zhao, H. (2007b) A new protocol of analyzing isotope-coded affinity tag data from high-resolution LC-MS spectrometry. Comput. Biol. Chem 31, 215-221. , (PMID: 17499548).

  31. Zoncu, R., Perera, R.M., Sebastian, R., Nakatsu, F., Chen, H., Balla, T., Ayala, G., Toomre, D. and De Camilli, P.V. (2007) Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate. Proc. Natl. Acad. Sci. U. S. A 104, 3793-3798. (PMID: 17360432).

  32. Bjornson, R.D., Carriero, N.J., Colangelo, C., Shifman, M., Cheung, K.H., Miller, P.L. and Williams, K. (2008) X!!Tandem, an improved method for running X!tandem in parallel on collections of commodity computers. J Proteome. Res 7, 293-299. (PMID: 17902638).

  33. Chen, L., Tong, T., Zhao, H., (2008) Considering dependence among genes and markers for false discovery control in eQTL mapping. Bioinformatics, 24: 2015-2022. (PMID: 18635565)

  34. Frost, A., Perera, R., Roux, A., Spasov, K., Destaing, O., Egelman, E.H., De Camilli, P. and Unger, V.M. (2008) Structural basis of membrane invagination by F-BAR domains. Cell 132, 807-817. (PMID: 18329367).

  35. Gong, L.W., and De Camilli P. (2008) Regulation of postsynaptic AMPA responses by synaptojanin I. Proc. Nat. Acad. Sci. 105: 17561-17566, (PMID: 18987319).

  36. Hayashi, M., Raimondi, A., O'Toole E, Paradise S, Collesi C, Cremona O, Ferguson SM, and De Camilli, P. (2008) Cell and stimulus dependent heterogeneity of synaptic vesicle endocytic recycling revealed by studies of dynamin 1-null neurons. Proc. Nat. Acad. Sci. 105: 2175-2180, (PMID: 18250322).

  37. Liu, J., Yu, W., Wu, B. and Zhao, H. (2008) Bayesian mass spectra peak alignment from mass charge ratios. Cancer Informatics. 6: 217-241.

  38. Liu, Y., Kim, I., Zhao, H., (2008) Protein interaction predictions from diverse sources. Drug Discovery Today, 13: 409-416 (PMID: 18468558)

  39. Pan, W., S.C. Choi, H. Wang, Y. Qin, L. Volpicelli-Daley, L. Swan, L. Lucast, C. Khoo, X. Zhang, L. Li, C.S. Abrams, S.Y. Sokol, and D. Wu, (2008) Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science 321(5894): 1350-3, (PMID: 18772438).

  40. Tong, T., Zhao, H., (2008) Practical guidelines for assessing power and false discovery rate for a fixed sample size in microarray experiments. Statistics in Medicine, 27: 1960-1972. (PMID: 18338314)

  41. Voronov, S.V., Frere, S.G., Giovedi, S., Pollina, E. A., Schmidt, C., Akeson, E.C., Wenk, M.R., Zhang, H., Cimasoni, L., Borel, C., Antonorakis, S.E., Arancio, O., Davisson, M.T., Gardiner, K., De Camilli, P. and Di Paolo, G. (2008) SYNJ1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down Syndrome. Proc. Nat. Acad. Sci. 105: 9415-9420, (PMID: 18591654).

  42. Yu, W., He, Z., Liu, J. and Zhao, H. (2008) Improving mass spectrometry peak detection using multiple peak alignment results. J Proteome. Res 7, 123-129. (PMID: 18030999).

  43. Frost A, Unger VM and De Camilli P. (2009) The BAR domain superfamily: Membrane-molding macro-molecules. Cell. 137: 191-196. (PMID: 19379681)

  44. Hirunsatit, R., George, E.D., Lipska, B.K., Elwafi, H.M., Sander, L., Yrigollen, C.M., Gelernter, J., Mutirangura, A., Grigorenko, E.L., Lappalainen, J., Nairn, A.C., Kleinman, J.E., and Simen. A.A. (2009) A 21-bp insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter. Pharmacogenetics and Genomics. 19: 53-65, (PMID: 19077666).

  45. Laurén, J., Gimbel, D.A., Nygaard, H.B., Gilbert JW, Strittmatter SM. (2009) Cellular Prion Protein Mediates Impairment of Synaptic Plasticity by Amyloid-ß Oligomers. Nature 457(7233):1128-32 (PMID: 19242475).

  46. Li, X., Zhao, H. (2009) Weighted random subspace method for high dimensional data classification. Statistics and Its Interfaces, in press.

  47. Liu,Y., Kim, I., Zhao, H., (2009) Protein interaction predictions from diverse sources. New Developments in Biostatistics and Bioinformatics, in press.

  48. Mao, Y.S., Yamaga M, Zhu X, Wei Y, Sun HQ, Wang J, Yun M, Wang Y, Di Paolo G, Bennett M, Mellman I, Abrams CS, De Camilli, P., Lu CY, and Yin H. (2009) Essential and unique roles of PIP5K-g and -a in FCg receptor-mediated phagocytosis. J. Cell Biol 184: 281-296.

  49. Mao, Y., Balkin, D. M., Zoncu, R., Erdmann, K., Tomasini, L., Hodsdon, M. E., De Camilli, P. (2009) A PH domain within the Lowe Syndrome protein OCRL bridges clathrin mediated membrane trafficking to phosphoinositide metabolism. EMBO J., in press.

  50. McCrea H and De Camilli P (2009) Mutations in Phosphoinositide Metabolizing Enzymes and Human Disease, Physiology. 24:8-16.(PMID:19196647)

  51. Rinehart, J., Maksimova, Y.D. , Tanis, J.E., Stone, K.E., Zhang, J., Risinger, M., Pan, W., Wu, D., Colangelo, C.M., Forbush, B., Joiner, C.H., Gulcicek, E.E., Gallagher, P.G., Lifton, R.P. (2009) Phosphoproteomic characterization of K-Cl cotransport: Implications for cell volume and neuronal excitability. Cell, in press,

  52. Pang, H., Tong, T., Zhao H., (2009) Shrinkage-based diagonal discriminant analysis and its applications in high-dimensional data. Biometrics, in press.

  53. Stone, K.L. , Gulcicek E. E. and Williams, K.R (2009a) Enzymatic Digestion of Proteins in Solution and in SDS Polyacrylamide Gels in The Protein Protocols Handbook, 3rd edition (Walker, J., ed.) 901-913.

  54. Stone, K.L. and Williams, K.R (2009b) Reverse-Phase HPLC Separation of Enzymatic Digests of Proteins in The Protein Protocols Handbook, 3rd edition (Walker, J., ed.) 937-946.

  55. Vasudevan L, Jeromin A, Volpicelli-Daley L, De Camilli P, Holowka D, and Baird B. 2009. The b and g isoforms of type I PIP5 kinase regulate distinct stages of Ca2+ signaling in mast cells. J. Cell Sci. in press.

  56. Zoncu, R., Perera, R., Balkin DM, Toomre D, and De Camilli P. (2009) A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell 136, 1110-1121. (PMID: 19303853)

Abstracts of Posters:

  1. Olausson, P., Tronson, N.C., Kiraly, D.D., Krueger, D.D., Nairn, A.C. and Taylor, J.R. (2004) Selective cognitive-motivational alterations following prior cocaine exposure in monkeys. Program # 671.10. Society for Neuroscience. Washington, DC.

  2. Zimolo Z, Krystal JH, Perry EB, Wu T, Vangala S, Williams K, D’Souza DC. (2004) Proteomic analysis of glutamate modulation with riluzole in schizophrenia. Society for Neuroscience.

  3. Andrade, E.C., Wu, T., Colangelo, C., Lam, T., Berberich, M., Stone, K., Allen, P.B., Taylor, J.R., Williams, K.R. and Nairn, A.C. (2005) Identification of alterations in synaptic protein composition following chronic cocaine exposure in mice. Program # 1030.5. Society for Neuroscience.

  4. Berberich, M., Stone, K., LoPresti, M., Weissman, S., Williams, K. and Colangelo, C. (2005) A comprehensive cellular snapshot using multiple protein profiling technologies. 53rd ASMS Conference on Mass Spectrometry, June 5 - 9, 2005 San Antonio, TX.

  5. Gulcicek, E., Berberich, M., Colangelo, C., Lam, T., McMurray, W., Stone, K. and Williams, K.R. (2005) Mass Spectrometric Integration of Robust Phosphoprotein Profiling Strategies. 53rd ASMS Conference on Mass Spectrometry, June 5 - 9, 2005, San Antonio, TX.

  6. Hager, J., Tikhonova, I., Clarke, L., Voss, E., Lui, J., Zhao, H., Strittmatter, S., Nairn, A. and Williams, K. (2005) Establishing protocols for making and using protein arrays in an academic core facility. Chips-to-Hits Meeting, September 11-15, 2005, Boston, MA.

  7. Krueger, D.D., Olausson, P., Wu, T., Williams, K.R., Taylor, J.R. and Nairn, A.C., (2005) Proteomic analysis of persistent cortico-limbic-striatal neuroadaptations following repeated cocaine exposure in vervet monkeys. Program # 1030.6. Society for Neuroscience.

  8. Lam, T., McMurray, W., Stone, K., Gulcicek, E., Colangelo, C. and Williams, K. (2005) Optimization of multi-dimensional protein identification technologies (MudPIT) for Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. 53rd ASMS Conference on Mass Spectrometry, June 5 - 9, 2005 San Antonio, TX.

  9. Shifman, M., Sun, K., Colangelo, C., Cheung, K., Miller, P. and Williams, K. (2005) YPED: A Proteomics Database for Protein Expression Analysis. Symposium of American Medical Informatics Association (AMIA), October 22-26, 2005, Washington, DC.

  10. Yu, W., Li, X., Liu, J., Wu, B., Williams, K. and Zhao, H. (2005) Aligning peaks across multiple mass spectrometry data sets using a scale-space based approach. IEEE Computational Systems Bioinformatics Conference (CSB 2005), August 8-11, 2005, Stanford, CA.

  11. Zimolo, Z., D'Souza, D.C., Perry, E., Krystal, J.H., Wu, T., Stone, K. and Williams, K. (2005) Proteomic analysis of antipsychotic response. International Congress on Schizophrenia Research 2005. Savannah, GA.

  12. Andrade, E., Colangelo, C., Berberich, M., Allen, P., Taylor, J.R., Williams, K.R. and Nairn, A.C. (2006) Identification of alterations in synaptic protein composition in cortico-limbic-striatal brain regions after chronic cocaine exposure in mice. Society for Neuroscience.

  13. Collin-Hansen, C, Gulcicek, E.E., Wu, T., Williams, K.R. and Nairn, A.C. (2006b) Development of a robust strategy for the enrichment of phosphorylated proteins and peptides from complex mixtures. 54th ASMS Conference on Mass Spectrometry, May 28 – June 1, 2006

  14. Collin-Hansen, C., Gulcicek, E.E., Wu, T., Williams, K.R. and Nairn, A.C. (2006a) Comparison of methods for enrichment of phosphoproteins and phosphopeptides from complex samples. Poster # 99.11/OO91, Atlanta, GA: Society for Neuroscience, Oct. 14, 2006.

  15. Gulcicek, E.E. (2006) Protein and Phosphoprotein Profiling Strategies. The 4th International Forum on Post-Genome Technologies. September 25 – 26, 2006, Hongzhou, China. Invited Keynote speaker.

  16. Gulcicek, E.E., Shifman, M.A., Miller, P., Colangelo, C.M., Stone, K.L., Lam, T.T. and Bruce, C. (2006) High Probability MS Identification of Phosphopeptides by their Mass Defect. 54th ASMS Conference on Mass Spectrometry, May 28 – June 1, 2006.

  17. Haspeslagh, D.C., Olausson, P., Taylor, J.R. and Allen, P.B. (2006) Spinophilin, a Synaptic Scaffolding Protein, Regulates Dopamine Signal Transduction Efficacy. Poster # C75/723.6. Society for Neuroscience, Oct. 14, 2006, Atlanta, GA.

  18. Andrade, E., Horiuchi, A., Wu, T., Mane, S., Stone, K., Greengard, P. and Nairn, A. (2007) The role and regulation of ARPP-16/19 in neurons. Society for Neuroscience, 2007 Meeting.

  19. Collin-Hansen, C., Gulcicek, E.E., Williams, K.R., Colangelo, C.M., Stone, K.L. and Nairn, A.C. (2007) Phosphoproteome of Synaptoneurosomes from Cocaine Treated Rats, 55th ASMS Conference on Mass Spectrometry, Indianapolis, IN.

  20. Fogel, A.I., Akins, M., Krupp, A., Stagi, M., Stein, V. and Biederer, T. (2007) SynCAMs 1/2 comprise a novel adhesion complex at central synapses. Poster # 571.7/H3. Society for Neuroscience, November 3 – 7, 2007, San Diego, California.

  21. Kedves, A., Olausson, P., Krueger, D., Colangelo, C., Williams, K. Nairn, A., Taylor, J. (2007) Proteomic analysis of synaptic cortico-striatal neuroadaptations following repeated PCP exposure in Vervet monkeys. Poster # 498.22/HH3. Society for Neuroscience, November 3 – 7, 2007, San Diego, California

  22. Olausson, P., Krueger, D., Colangelo, C., Williams, K., Nairn, A. and Taylor, J. (2007) Proteomic analysis of persistent cortico-striatal synaptic neuroadaptations following repeated cocaine exposure in Vervet monkeys. Poster # 272.13/Z26. Society for Neuroscience, November 3 – 7, 2007, San Diego, California.

  23. Taylor, J.R. and Olausson, P. (2007) Orbitofrontal cortex and addiction; Evidence from Primate Experiments. New York Academy of Science Meeting, " Linking Affect to Action; Critical Contributions of the Orbitofrontal Cortex," March 11 – 14, 2007, New York, NY.

  24. Sathyanesan, S.N., Girgenti, M.J. and Sathyanesan, M (2007). A Genomics and Proteomics Characterization of the Choroid Plexus: Implications for Antidepressant Action. Poster # 908.5/DD24. Society for Neuroscience, November 3 – 7, 2007, San Diego, California.

  25. Stone, K., Colangelo, C., Gulcicek, E., Lam, T., Wu, T., LoPresti, M., Abbott, T., Crawford, M., Williams, N., Kanyo, J., Wilczak-Havill, K., Shifman, M. and Williams, K. (2007) Information on the MS & Proteomics Resource at Yale University. Northeast Regional Life Sciences Core Director Meeting, November 7, 2007, Cornell University, Ithaca, NY.

  26. Zimolo, Z., Stone, K., Wu, T., Colangelo, C., D'Souza, D.C., Williams, K. and Krystal, J.H. (2007) Plasma proteomic biomarkers in schizophrenia. International Congress on Schizophrenia Research, Colorado Springs, CO.

  27. Andrade, E.C., Colangelo, C., Wilczak-Havil, K., Taylor, J.R., Williams, K.R., Nairn, A.C., (2008) Identification of alterations in synaptic protein composition in cortico-limbic-striatal brain regions following chronic cocaine exposure in rats. Society for Neuroscience Meeting, Washington DC. November, 2009.

  28. Biederer, T., Fogel, A.I., Stagi, M., Krupp, A. and Stein, V. (2008) SynCAMs organize synapses through heterophilic adhesion. Keystone Symposia, Molecular Basis for Biological Membrane Organization, January 13, 2008, Big Sky, MT.

  29. Bruce, C., Williams, K. and Gulcicek, E.E. (2008) Identification of Sites of Phosphorylation from Tandem Spectrometry Data by Logical Analysis of Result Classes. US HUPO Meeting, March 17, 2008, Washington, DC.

  30. Fleming, M.R., Yan, Y., Lam, T., Gulcicek, E., Nairn, A. and Kaczmarek, L.K. (2008). Regulation of Sodium-Activated Potassium (KNa) Channels by Phosphorylation. Soc. Neurosci. Abstr. (CD ROM) 430.18,

  31. Kedves AT, Olausson P, Nairn AC, Taylor JR (2008) Striatal Neuroadaptations Regulated by the Transcription Factor Sp1 are Induced by Chronic Cocaine Exposure in Rodents. Poster # 663.10/JJ5. Society for Neuroscience, November 14 – 19, 2008, Washington, DC.

  32. Olausson P, Krueger DD, Kedves AT, Nairn AC and Taylor JR (2008) Synaptic neuroadaptations following repeated cocaine exposure in Vervet monkeys – a proteomics analysis of the frontal cortex. Poster # 663,5/II30. Society for Neuroscience, November 14 – 19, 2008, Washington, DC.

  33. Stipanovich, A., Wei, F.-Y., Lavaur, J., Stone, K., Colangelo, C., Gulcicek, E., Picciotto, M.R., Cedars, E., Greengard, P., Nairn, A.C. (2008) Characterization of the phosphorylation sites of the neuronal RhoGEF Lfc. Society for Neuroscience Meeting, Washington DC. November, 2008.

  34. Stone, K., Wu, T., Gulcicek, E., Shifman, M., Kanyo, J., Colangelo, C. and Williams, K. (2008) The Art of DIGE. ABRF, Enabling Technologies in the Life Sciences, February 9, 2008, Salt Lake City, UT

  35. Stone, K., Colangelo, C., Gulcicek, E., Lam, T., Wu, T., LoPresti, M., Abbott, T., Crawford, M., Williams, N., Kanyo, J., Wilczak-Havill, K., Shifman, M. and Williams, K. (2008) The Mass Spectrometry and Proteomics Resource of the Keck Laboratory at Yale University. ABRF, Enabling Technologies in the Life Sciences, February 9, 2008, Salt Lake City, UT.

  36. Gulcicek, Erol E.; K. L Stone; C. Bruce; R. I. Herzog; R. S. Sherwin (2009), Improved sample preparation for phosphoproteome analysis of rat brain tissue, 57th ASMS Conference on Mass Spectrometry, May 31 – June 4, Philadelphia, PA.

  37. Rinehart, Jesse; Y. D. Maksimova; J. E. Tanis; K. Stone; J. Zhang; M. Risinger; W. Pan; D. Wu; C. Colangelo; B. Forbush; C. H. Joiner; E. E. Gulcicek; P. G. Gallagher; R. P. Lifton, (2009) Quantitative phosphoproteomics identifies sites in K-Cl cotransporters that regulate cell volume and neuronal excitation, 57th ASMS Conference on Mass Spectrometry, May 31 – June 4, Philadelphia, PA.

  38. Voss, E., Biederer, T., Wu, T., Easterling, M.L., LoPresti, M., Williams, K.R., Lam, T.T. (2009) Method Optimization for the Determination of Protein Site of N-Glycosylation: Case Study for SynCAM1, 57th ASMS Conference on Mass Spectrometry, May 31 - June4, 009, Philadelphia, PA.

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Last modified: 23-May-2008 (GB)