Neurosurgery
P.O., Box 208082
New Haven, CT 06520-8082
Tel: 203.785.2805
Fax: 203.785.6916
neurosurgery@yale.edu
Dr. Peter Patrylo is an Associate Research Scientist in Neurosurgery. In addition to Dr. Patrylo's involvement with Dr. Ann Williamson regarding epileptogenesis, he has initiated a series of studies on whether synaptic connectivity changes with age.
Recent Publications
Williamson, A. and Patrylo, P. Regulation of excitability in the epileptic human hippocampus. 1999. The Neuroscientist 5:362-370.
Williamson, A., Patrylo, P.R. and Spencer, D.D. 1999. Decrease in inhibition in dentate granule cells from patients with medial temporal lobe epilepsy, Annals of Neurology 45:92-99.
Williamson, A., Patrylo, P.R. and Spencer, D.D. 1999. Decrease in inhibition in dentate granule cells from patients with medial temporal lobe epilepsy, Annals of Neurology 45:92-99.
Williamson, A. and Patrylo, P. Regulation of excitability in the epileptic human hippocampus. 1999. The Neuroscientist 5:362-370.
Patrylo, P.R., Spencer, D.D, van den Pol, A., and Williamson, A. 1999. NPY inhibits glutamateric excitation in the epileptic human hippocampus. J Neurophysiol 82:478-83.
Hellier JL, Patrylo PR, Dou P, Nett M, Rose GM, Dudek FE. 1999. Assessment of inhibition and epileptiform activity in the septal dentate gyrus of freely behaving rats during the first week after kainate treatment. J Neurosci. 19:10053-64.
Patrylo PR, Schweitzer JS, Dudek FE. 1999. Abnormal responses to perforant path stimulation in the dentate gyrus of slices from rats with kainate-induced epilepsy and mossy fiber reorganization. Epilepsy Res. 36:31-42.
Liu QS, Patrylo PR, Gao XB, van den Pol AN. 1999. Kainate acts at presynaptic receptors to increase GABA release from hypothalamic neurons. J Neurophysiol. 82:1059-62.
van den Pol AN, Gao XB, Patrylo PR, Ghosh PK, Obrietan K. 1998 Glutamate inhibits GABA excitatory activity in developing neurons. J Neurosci. 1998 18:10749-61.