Publications

Selected papers

Li Y , van den Pol AN (2008) Mu-opioid receptor-mediated depression of the hypothalamic hypocretin/orexin arousal system J. Neurosci. 28: 2814-2819.

Ozduman K, Wollmann G, Peipmeier J, van den Pol AN (2008)   Systemic vesicular stomatitis virus selectively destroys multifocal glioma and metastatic carcicoma in brain. J. Neurosci. 28: 1882-1893.

Tsunematsu,T, Fu LY, Yamanaka A, Ichiki K, Tanoue A, Sakurai T, van den Pol A (2008) Vasopressin increases locomotion through a V1a receptor in orexin/hypocretin neurons- implications for water homeostasis. J. Neurosci. 28: 228-238.

Huang H, van den Pol AN (2007) Rapid direct excitation and long-lasting enhancement of NMDA response by group I metabotropic glutamate receptor activation of hypothalamic melanin-concentrating hormone neurons. J. Neurosci. 27: 11560-11572.

Ho WSC, van den Pol AN (2007) Bystander attenuation of neuronal and astrocyte intercellular communication by murine cytomegalovirus infection of glia. J. Virol. 81: 7286-7292.

Huang H, Acuna-Goycolea C, Li Y, Cheng HM, Obrietan K, van den Pol AN (2007) Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit hypocretin/orexin neurons: implications for cannabinoid actions on food intake and cognitive arousal. J. Neurosci. 27: 4870-4881.

Fu LY, van den Pol AN (2007) GABA excitation in mouse hilar neuropeptide Y neurons. J. Physiol. 579: 445-464.

Wollmann G, Robek MD, van den Pol AN (2007) Variable deficiencies in the interferon response enhance susceptibility to VSV oncolytic actions in glioblastoma but not in normal human glia. J. Virol. 81: 1479-1491.

van den Pol AN, Robek MD, Ghosh PK, Ozduman K, Bandi P, Whim MD, Wollmann G (2007) Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain. J. Virol. 81: 332-348.

Li Y, van den Pol AN (2006)   Differential target dependent actions of coexpressed inhibitory dynorphin and excitatory hypocretin/orexin neuropeptides. J. Neurosci. 26: 13037-13047.

van den Pol AN (2006) Viral infections in the developing and mature brain. Trends Neurosci. 29: 398-406.

Huang H, Ghosh P, van den Pol AN (2006) Prefrontal cortex-projecting glutamate thalamic paraventricular nucleus excited by hypocretin: feedforward circuit that may enhance cognitive arousal. J. Neurophys. 95: 1656-1668.

van den Pol AN (2005) Physiological characteristics of hypocretin/orexin neurons. In Hypocretin- Integrators of physiological functions. Eds. L de Lecea and JJ.G. Sutcliffe, Springer, New York, 123-136

Acuna-Goycolea C, van den Pol AN (2005) Peptide YY(3-36) inhibits both anorexigenic proopiomelanocortin and orexigenic neuropeptide Y neurons: implications for hypothalamic regulation of energy homeostasis. J. Neurosci. 25: 10510-10519.

Acuna-Goycolea C, Tamamaki N, Yanagawa Y, Obata K, van den Pol AN (2005) Mechanisms of neuropeptide Y, peptide YY, and pancreatic polypeptide inhibition of identified green fluorescent protein-expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus. J. Neurosci. 25: 7406-7419.

Wollmann G, Acuna-Goycolea C, van den Pol AN (2005) ATP Direct excitation of hypocretin/orexin cells by extracellular ATP at P2X receptors. J. Neurophsyiol. 94: 2195-2206.

van den Pol AN, Acuna-Goycolea C (2006) Neuronal responses to hypocretin/orexin. In The Orexin/Hypocretin System: Physiology and Pathophysiology, Eds: Nishino S, Sakurai T, Humana Press, Totowa, NJ. 45-60.

Huesa G, van den Pol AN, Finger, T (2005) Differential distribution of hypocretin (orexin) and melanin concentrating hormore in goldfish brain. J. Comp. Neurol. 488: 476-491.

Reuter JD, Wilson JH, Idoko KE, van den Pol AN (2005) CD4 T-cell reconstitution reduces cytomegalovirus in immunocompromised brain. J. Virol. 79: 9527-9539.

Wollmann G, Tattersall P, van den Pol AN (2005) Targeting human glioblastoma cells-comparison of nine viruses with oncolytic potential. J. Virol. 79: 6005-6022.

Li Y, van den Pol AN (2005) Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons. J. Neurosci. 25: 173-183.

Fu LY, Acuna-Goycolea C, van den Pol AN (2004) Neuropeptide Y inhibits hypocretin/orexin neurons by multiple presynaptic and postsynaptic mechanisms: tonic depression of the hypothalamic arousal system. J. Neurosci. 24: 8741-8751.

Acuna-Goycolea C, van den Pol A (2004) Glucagon-like peptide 1 excites hypocretin/orexin neurons by direct and indirect mechanisms: implications for viscera-mediated arousal. J. Neurosci. 24: 8141-8152.

van den Pol AN, Acuna C, Clark R, Ghosh PK (2004) Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection infection. Neuron 42: 635-652.

Wu M, Zaborszky L, Hajszan T, van den Pol AN, Alreja M (2004) Hypocretin/orexin innervation and excitation of identified septohippocampal cholinergic neurons. J. Neurosci. 24:3527-3536.

Acuna-Goycolea C, Li Y, van den Pol AN (2004) Group 3 metabotropic glutamate receptors maintain tonic inhibition of excitatory synaptic input to hypocretin/orexin neurons. J. Neurosci. 24:3013-3022.

Reuter JD, Gomez DL, Wilson JH, van den Pol AN (2004) Systemic immune deficiency necessary for cytomegalovirus invasion of the mature brain. J Virol. 78:1473-1487.

Hantman AW, van den Pol AN, Perl ER (2004) Morphological and physiological features of a set of spinal substantia gelatinosa neurons defined by green fluorescent protein expression. J. Neurosci. 24:836-842.

van den Pol AN (2004) Developing neurons make the switch. Nature Neurosci. 7: 7-8.

van den Pol AN (2003) Weighing the role of hypothalamic feeding neurotransmitters. Neuron 40: 1059-1061.

Gao XB, Ghosh PK, van den Pol AN (2003) Neurons synthesizing MCH identified by selective reporter gene expression after transfection in vitro: transmitter responses. J. Neurophysiol. 90: 3978-3985.

van den Pol AN, Santarelli JG (2003) Olfactory ensheathing cells: time lapse imaging   of cellular interactions, axonal support, rapid morphological shifts, and mitosis. J. Comp Neurol. 458:175-194.

Li Y, Gao XB, Sakurai T, van den Pol AN (2002) Hypocretin/orexin excites hypocretin neurons via a local glutamate neuron- a potential mechanism for orchestrating the hypothalamic arousal system. Neuron 36: 1169-1181.

Liu RJ, van den Pol AN, Aghajanian GK (2002) Hypocretins (Orexins)regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions. J. Neurosci. 22: 9453-9464.

Grudt TJ, van den Pol AN, Perl ER (2002) Hypocretin-2 (orexin-B) modulation of superficial dorsal horn activity in rat. J. Physiol. 538: 517-525.

van den Pol AN, Dalton KP, Rose JK (2002) Relative neurotropism of recombinant rhabdovirus expressing a green fluroescent envelope glycroprotein. J. Virol.76: 1309-1327.

Gao XB, van den Pol AN (2002) Melanin-concentrating hormone depresses L-, N- and P/Q-type voltage-dependent calcium channels in rat lateral hypothalamic neurons. J. Physiol. 542: 273-286.

Obrietan K, Gao XB, van den Pol AN (2002) Exitatory actions of GABA increase BDNF expression via a MAPK-CREB-dependent mechanism-a positive feedback circuit in developing hypothalamic neurons. J. Neurophysiol. 88: 1005-1015.

van den Pol AN, Ghosh PK, Liu R, Li Y, Aghajanian GK, Gao XB (2002) Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus. J. Physiol. 541: 169-185.

Mitome M, Low HP, van den Pol AN, Nunnari JJ, Wolf MK, Billings-Gagliardi S, Schwartz WJ (2001) Towards the reconstruction of central nervous system white matter using neural precursor cells. Brain 124: 2174-2161.

van den Pol AN, Patrylo PR, Ghosh PK, Gao XB (2001) Lateral hypothalamus- Early developmental expression and response to hypocretin (orexin). J. Comp. Neurol. 433: 349-363.

Gao XB, van den Pol AN (2001) Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus. J. Physiol. 533: 237-252.

Mintz EM, van den Pol AN, Casano AA, Albers HE (2001) Distribution of hypocretin-2 immunoreactivity in the central nervous system of Syrian hamsters (Mesocricetus auratus). J. Chem. Neuroanat. 21: 225-238.

Wang YF, Gao XB, van den Pol AN (2001) Membrane properties underlying patterns of GABA-dependent action potentials in developing mouse hypothalamic neurons. J. Neurophysiol. 86: 1252-65.

Gao XB, van den Pol AN (2001) GABA, not glutamate, a primary excitatory transmitter in developing hypothalamus. J. Neurophysiol. 85: 425-434.

Galas L, Vaudry H, Braun B, van den Pol AN, De Lecea L, Sutcliffe JG, Chartrel N (2001) Immunohistochemical localization and biochemical characterization of hypocretin/ orexin-related peptides in the central nervous system of the frog Rana ridibunda. J. Comp. Neurol. 429: 242-252.

van den Pol AN (2000) Narcolepsy, a neurodegenerative disease of the hypocretin system? Neuron, 27: 415-418.

van den Pol AN, Vieira J, Spencer DD, Santarelli JG (2000) Mouse cytomegalovirus in developing brain tissue - analysis of 11 species with GFP-expressing recombinant virus. J. Comp. Neurol. 427: 559-580.

Gao XB, van den Pol AN (2000) GABA release from mouse axonal growth cone. J. Physiol. 523: 629-637.

van den Pol AN, Obrietan K (2000) Neuromodulation of GABA in developing and mature hypothalamic neurons. In GABA in the Nervous System. Edited by D.L.Martin and R.W.Olsen, Lippincott, Williams, and Wilkins Press, Philadelphia, PA. 409-438.

van den Pol AN, Spencer D (2000) Differential neurite growth on astrocyte substrates: interspecies facilitation in green fluorescent protein transfected rat and human neurons. Neuroscience. 95: 603-616.

van den Pol AN, Mocarski E, Saederup N, Vieira J, Meier TJ (1999) Cytomegalovirus cell tropism, replication, and gene transfer in brain. J. Neurosci. 19: 10948-10965.

Horvath TL, Peyron C, Diano S, Ivanov A, Aston-Jones G, Kilduff TS, van den Pol AN (1999) Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. J. Comp. Neurol. 415: 145-159.

Patrylo P, van den Pol AN, Spencer DD, Williamson A (1999) NPY inhibits glutamatergic excitation in the epileptic human dentate gyrus. J. Neurophysiol. 82: 478-483.

Liu OS, Patrylo PR, Gao XB, van den Pol AN (1999) Kainate acts at presynaptic receptors to increase GABA release from hypothalamic neurons. J. Neurophysiol. 82: 1059-1062.

Gao XB, van den Pol AN (1999) Neurotrophin-3 potentiates excitatory GABAergic synaptic transmission in cultured developing hypothalamic neurones of the rat. J. Physiol. 518: 81-95.

van den Pol AN (1999) Hypothalamic hypocretin (orexin): robust innervation of the spinal cord. J. Neurosci. 19: 3171-3182.

Obrietan K, van den Pol AN (1999) GABAB receptor-mediated regulation of glutamate activated calcium transients in hypothalamic and cortical neurons during development in vitro. J. Neurophysiol. 81: 94-102.

Horvath TL, Diano S, van den Pol AN (1999) Synaptic interaction between hypocretin (orexin) containing neurons and arcuate nucleus NPY-producing cells in rodent and primate- a new hypothalamic circuit implicated in energy homeostasis. J. Neurosci. 19: 1072-1087.

Peyron C, Tighe DK, van den Pol AN, de Lecea L, Heller HC, Sutcliffe JG, Kilduff TS (1998) Neurons containing the novel hypothalamic peptide hypocretin (orexin) project to multiple neuronal systems. J. Neuroscience. 18: 9996-10015.

van den Pol AN, Ghosh P (1998) Selective neuronal expression of green fluorescent protein with cytomegalovirus promoter reveals entire neuronal arbor in transgenic mice. J. Neurosci. 18: 10640-10651.

van den Pol AN, Gao XB, Patrylo P, Ghosh P, Obrietan K (1998) Glutamate inhibits GABA excitatory activity in developing neurons. J. Neurosci. 18: 10749-10761.

van den Pol AN, Gao XB, Obrietan K, Kilduff T, Belousov A (1998) Pre- and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin. J. Neurosci. 18: 7962-7971.

van den Pol AN, Obrietan K, Belousov A, Yang Y, Heller HC (1998) Early synaptogenesis in vitro: role of axon target distance. J. Comp. Neurol. 399: 541-560.

van den Pol AN, Cao V, Heller HC (1998) Circadian system of mice integrates brief light stimuli. Am. J. Physiol. 275: R654-R657.

Chen G, van den Pol AN (1998) Coexpression of multiple metabotropic glutamate receptors in axon terminals of single suprachiasmatic nucleus neurons. J. Neurophysiol. 80: 1932-1938.

de Lecea L, Kilduff TS, Peyron C, Gao XB, Foye PE, Danielson PE, Fukuhara C, Battenberg ELF, Gautvik VT, Bartlett II FS, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG (1998) The hypocretins: two hypothalamic peptides with neuroexcitatory activity. Proc Natl Acad Sci USA. 95: 322-327.

Gribkoff V, Pieschl RL, Wisialowski WA, van den Pol AN, Yocca FD (1998) Phase-shifting of circadian rhythms and depression of neuronal activity in the rat suprachiasmatic nucleus by neuropeptide Y: mediation by different receptor subtypes. J. Neurosci. 18: 3014-3022.

Chen G, van den Pol AN (1998) Presynaptic GABA-B autoreceptor modulation of P/Q type calcium channels and GABA release in rat suprachiasmatic nucleus neurons J. Neurosci. 18: 1913-1922.

Obrietan K, van den Pol AN (1998) GABA-B receptor mediated inhibition of GABA-A receptor calcium elevations in developing hypothalamic neurons. J. Neurophysiol. 79: 1360-1370.

Gao, XB, Chen G, van den Pol AN (1998) GABA-dependent firing of glutamate-evoked action potentials at non-NMDA receptors in developing hypothalamic neurons. J. Neurophysiol. 79: 716-726.

Belousov A, van den Pol AN (1997) Dopamine inhibition: enhancement of GABA activity and potassium channel activation in hypothalamic and arcuate nucleus neurons. J. Neurophysiol. 78: 674-688.

Obrietan K, van den Pol AN (1997) GABA activity mediating cytosolic Ca2+ rises in developing neurons is modulated by cAMP-dependent signal transduction. J. Neurosci. 17: 4785-4799.

Ghosh PK, Baskaran N, van den Pol AN (1997) Developmentally regulated gene expression of all eight metabotropic glutamate receptors in hypothalamic SCN and arcuate nuclei--a PCR analysis. Dev. Brain Res. 102: 1-12.

van den Pol AN (1997) GABA, excitatory transmitter after trauma. Neuroscientist. 3: 281-286.

Kinzie J, Shinohara M, van den Pol AN, Westbrook G, Segerson T (1997) Immunolocalization of metabotropic glutamate receptor 7 in the adult rat olfactory bulb. J. Comp. Neurol. 385: 372-384.

Chen G, van den Pol AN (1997) Adenosine modulation of calcium currents and presynaptic inhibition of GABA release in SCN and arcuate nucleus neurons. J. Neurophysiol. 77: 3035-3047.

van den Pol AN (1997) GABA immunoreactivity in hypothalamic neurons and growth cones in early development in vitro prior to synapse formation. J. Comp. Neurol. 383:178-188.

Belousov A, van den Pol AN (1997) Local synaptic release of glutamate from neurons of the rat hypothalamic arcuate nucleus. J. Physiol. 499: 747-761.

Haak L, Heller HC, van den Pol AN (1997) Metabotropic glutamate receptor activation modulates kainate and serotonin calcium response in astrocytes. J. Neurosci. 17: 1825-1837.

Chen G, van den Pol AN (1996) Multiple NPY receptors coexist in pre- and postsynaptic sites: inhibition of GABA release in isolated self-innervating SCN neurons. J. Neurosci. 16: 7711-7724.

van den Pol AN, Obrietan K, Chen G, Belousov A (1996) Neuropeptide Y-mediated long-term depression of excitatory activity in suprachiasmatic nucleus neurons. J. Neurosci.16:5883-5895.

van den Pol AN, Cao V, Belousov A (1996) Dopamine modulation of glutamate-regulated calcium and electrical activity in hypothalamic neurons. J. Neurophysiol. 76: 3934-3948.

Obrietan K, van den Pol AN (1996) Growth cone calcium elevation by GABA. J. Comp. Neurol. 372: 167-175.

van den Pol AN, Obrietan K, Chen G (1996) Excitatory actions of GABA after neuronal trauma. J. Neurosci. 16: 4283-4292.

Chen G, Trombley P, van den Pol AN (1996) Excitatory actions of GABA in developing rat hypothalamic neurons. J. Physiol. 494: 451-464.

van den Pol AN, Obrietan K, Belousov A (1996) Glutamate hyperexcitability and seizure-like activity throughout the brain and spinal cord upon relief from chronic glutamate receptor blockade in culture. Neuroscience. 74: 653-674.

van den Pol AN, Strecker GJ, Dudek FE (1996) Excitatory and inhibitory amino acids and synaptic transmission in the suprachiasmatic nucleus. Prog. Brain Res. 111: 41-56.

Obrietan K, van den Pol AN (1996) Neuropeptide Y depresses GABA-mediated calcium transients in developing suprachiasmatic nucleus neurons: a novel form of calcium long-term depression. J. Neurosci. 16: 3521-3533.

Romano C, van den Pol AN, O'Malley KL (1996) Enhanced early developmental expression of the metabotropic glutamate receptor, mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution. J. Comp. Neurol. 367: 403-412.

Obrietan K, Belousov A, Heller HC, van den Pol AN (1995) Adenosine pre- and postsynaptic modulation of glutamate dependent calcium activity in hypothalamic neurons. J. Neurophysiol. 74: 2150-2162.

Chen G, Trombley PQ, van den Pol AN (1995) GABA receptors precede glutamate receptors in hypothalamic development; differential regulation by astrocytes. J. Neurophysiol. 74: 1473-1484.

van den Pol AN, Romano C, Ghosh P (1995) Metabotropic glutamate receptor mGluR5: subcellular d istribution and developmental expression in hypothalamus. J. Comp. Neurol. 362: 134-150.

Obrietan K, van den Pol AN (1995) GABA neurotransmission in the hypothalamus: developmental reversal from Ca2+ elevating to depressing. J. Neurosci. 15: 5065-5077.

van den Pol AN (1995) Presynaptic metabotropic glutamate receptors in adult and developing neurons: autoexcitation in the olfactory bulb. J. Comp. Neurol. 359: 253-271.

van den Pol AN, Wuarin JP, Dudek FE (1995) Glutamate neurotransmission in the neuroendocrine hypothalamus. In: Excitatory Amino Acids: Their Role in Neuroendocrine Function, Edited by D.W.Brann and V. Mahesh. CRC Press, Boca Raton, FL. 1-54.

Obrietan K, van den Pol AN (1995) Calcium hyperexcitability in neurons cultured with glutamate receptor blockade. J. Neurophysiol. 73: 1524-1536.

van den Pol AN, Obrietan K, Cao V, Trombley P (1995) Embryonic hypothalamic expression of functional glutamate receptors. Neuroscience. 67: 419-439.

Romano C, Sesma MA, MacDonald C, O'Malley K, van den Pol AN, Olney J (1995) Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. J. Comp. Neurol. 355: 455-469.

Liljelund P, Ghosh P, van den Pol AN (1994) Expression of the neural axon adhesion molecule L1 in the developing and adult rat brain. J. Biol. Chem. 269: 32886 -32895.

van den Pol AN (1994) Metabotropic glutamate receptor mGluR1 distribution and ultrastructural localization in hypothalamus. J. Comp. Neurol.. 349: 615-632.

van den Pol AN, Collins WF (1994) The paraventriculo-spinal tract as a model for axon injury spinal cord. J. Comp. Neurol. 349: 244-258.

van den Pol AN, Kogelman L, Ghosh P, Liljelund P, Blackstone C (1994) Developmental regulation of the hypothalamic glutamate receptor mGluR1. J. Neurosci. 14: 3816-3834.

van den Pol AN, Bina K, Decavel C, Ghosh P (1994) VGF expression throughout the brain. J. Comp. Neurol. 347: 455-469.

van den Pol AN, Hermans-Borgmeyer I, Hofer M, Ghosh P, Heinemann S (1994) Ionotropic glutamate-receptor gene expression in hypothalamus: localization of AMPA, kainate, and NMDA receptor RNA with in situ hybridization. J. Comp. Neurol. 343: 428-444.

van den Pol AN, Trombley PQ (1993) Glutamate neurons in hypothalamus regulate excitatory transmission. J. Neurosci. 13: 2829-2836.

van den Pol AN, Dudek FE (1993) Cellular communication in the circadian clock, the suprachiasmatic nucleus. Neuroscience. 56: 793-811.

van den Pol AN (1993) Glutamate and GABA presence and action in the suprachiasmatic nucleus. J. Biol. Rhythms. 8: S11-S15.

van den Pol AN, Kim WT (1993) NILE/L1 and NCAM-polysialic acid expression on growing axons of isolated neurons. J. Comp. Neurol. 332: 237-257.

van den Pol AN, Finkbeiner SM, Cornell-Bell AH (1992) Calcium excitability and oscillations in suprachiasmatic nucleus neurons and glia in vitro. J. Neurosci. 12: 2648-2664.

Decavel C, van den Pol AN (1992) Converging GABA- and glutamate-immunoreactive axons make synaptic contact with identified hypothalamic neurosecretory neurons. J. Comp. Neurol. 316: 104-116.

van den Pol AN (1991) The suprachiasmatic nucleus: morphological and cytochemical substrates for cellular interactions. In The Mind's Clock D.C.Klein, R.Y.Moore, S.M.Reppert (Eds) Oxford Univ.Press New York. 17-50.

van den Pol AN (1991) Glutamate and aspartate immunoreactivity in hypothalamic presynaptic axons. J. Neurosci.11: 2087-2101.

van den Pol AN (1990) Immunogold labeling for light, confocal and electron microscopy. In Handbook for Short Course: recent developments in microscopy. D.Agard, L.Peache (Eds.) Amer.Soc.Cell Biol. pp 204-224.

Decavel C, van den Pol AN (1990) GABA: a dominant neurotransmitter in the hypothalamus. J. Comp. Neurol. 302: 1019-1037.

van den Pol AN (1990) The suprachiasmatic nucleus: morphological and cytochemical substrates for cellular interaction. In Suprachiasmatic Nucleus: The Mind's Clock. Ed: D.Klein, R.Y.Moore, and S.M.Reppert. Oxford University Press, New York.

van den Pol AN, Gallyas F (1990) Trauma induced Golgi-like staining of neurons: a new approach to neuronal organization and response to injury. J. Comp. Neurol. 296: 654-673.

van den Pol AN, Wuarin JP, Dudek FE (1990) Glutamate, the dominant excitatory transmitter in neuroendocrine regulation. Science. 250: 1276-1278.

van den Pol AN, Decavel C (1990) Synaptic interaction between chemically defined neurons: Dual ultrastructural immunocytochemical approaches. pp. 199- 271. In Neuronal Microcircuits- Handbook of Chemical Neuroanatomy. Edited by: A.Bjorklund, T.Hokfelt, F.Wouterlood, A.N.van den Pol, Elsevier, Amsterdam.

van den Pol AN, Decavel C, Levi A, Patterson B (1989) Hypothalamic expression of a novel gene product, VGF: immunocytochemical analysis. J. Neurosci. 9: 4122-4137.

van den Pol AN (1989) Neuronal imaging with colloidal gold. J. Microsc. 155: 27-59.

Bjorklund A, Hokfelt T, Wouterlood F, van den Pol AN (1990) (Eds.) Neuronal Microcircuits-Handbook of Chemical Neuroanatomy. Elsevier, Amsterdam.

van den Pol AN, Ellisman M, Deerinck T (1989) Plasma membrane localization of proteins with gold immunocytochemistry. In Colloidal Gold: Methods and Applications. Edited by M.A.Hayat, Academic Press, Orlando. 451-488.

van den Pol AN (1988) Silver intensification of colloidal gold or horseradish peroxidase for dual ultrastructural immunocytochemistry. In Molecular Neuroanatomy Ed: van Leeuwen F, Buijs R, Pool C, Pach O; Elsevier Pub. Amsterdam. 315-336.

van den Pol AN, Gorcs T (1988) Glycine and glycine receptor immunoreactivity in brain and spinal cord. J. Neurosci. 8: 472-492.

van den Pol AN, Gorcs T (1986) Synaptic relationships between neurons containing vasopressin, gastrin releasing peptide, vasoactive intestinal polypeptide, and glutamate decarboxylase immunoreactivity in the suprachiasmatic nucleus: dual ultrastructural immunocytochemistry with gold substituted silver peroxidase. J. Comp. Neurol. 252: 507-521.

van den Pol AN, di Porzio U, Rutishauser U (1986) Growth cone localization of NCAM on central nervous system neurons in vitro. J. Cell Biol. 102: 2281-2294.

van den Pol AN (1986) Gamma-aminobutyrate, gastrin releasing peptide, serotonin, somatostatin, and vasopressin: ultrastructural immunocytochemical localization in presynaptic axons in the suprachiasmatic nucleus. Neuroscience. 17: 643- 659.

van den Pol AN (1986) Tyrosine hydroxylase immunoreactive neurons in the hypothalamus receive glutamate decarboxylase immunoreactive synapses- a double pre-embedding immunocytochemical study with particulate silver and HRP. J. Neurosci. 6: 877-891.

van den Pol AN (1985) Silver-intensified gold and peroxidase as dual ultrastructural immunolabels for pre- and postsynaptic neurotransmitters. Science. 228: 332-335.

van den Pol AN, Tsujimoto K (1985) Neurotransmitters of the hypothalamic suprachiasmatic nucleus: immunocytochemical analysis of 25 neuronal antigens. Neuroscience. 15: 1049-1086.

van den Pol AN, Smith AD, Powell J (1985) GABA axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry and biotin-peroxidase and protein-A colloidal gold. Brain Res. 348: 146-154.

van den Pol AN (1985) Dual ultrastructural localization of two neurotransmitter-related antigens: Colloidal gold labeled neurophysin immunoreactive supraoptic neurons receive peroxidase labeled glutamate decarboxylase or gold labeled GABA immunoreactive synapses. J. Neurosci. 5: 2940-2954.

van den Pol AN, Herbst RS, Powell JF (1984) Tyrosine hydroxylase- immunoreactive neurons of the hypothalamus: a light and electron microscopic study. Neuroscience. 13: 1117-1156.

van den Pol AN (1984) Colloidal gold and biotin-avidin conjugates as ultrastructural markers for neural antigens. Q. J. Exp. Physiol. 69: 1-33.

Vigh B, Vigh-Teichmann I, Manzano e Silva MJ, van den Pol AN (1983) Cerebrospinal fluid- contacting neurons of the central canal and terminal ventricle in various vertebrates. Cell Tissue Res. 231: 615-621.

van den Pol AN, Cassidy JR (1982) The hypothalamic arcuate nucleus of rat- a quantitative Golgi analysis. J. Comp. Neurol. 204: 65-98.

van den Pol AN (1982) The magnocellular and parvocellular paraventricular nucleus of rat: intrinsic organization. J. Comp. Neurol. 206: 317-345.

van den Pol AN (1982) Lateral hypothalamic damage and body weight regulation: a role of gender, diet, and lesion placement. Am. J. Physiol. 242: R265-274.

Vigh-Teichman I, Vigh B, Kausz M, Simonsberger P, van den Pol AN (1981) CSF contacting neuronal structures of the third ventricle of cat, hedgehog, and opossum. Mikroscopie. 38: 337-355.

van den Pol AN (1981) Amino acid incorporation in medial hypothalamic nuclei: circadian, perikarya and neuropil variations. Am. J. Physiol. 240: R16-R22.

van den Pol, AN (1980) The hypothalamic suprachiasmatic nucleus of rat: intrinsic anatomy. J. Comp. Neurol. 191: 661-702.

van den Pol AN, Powley T (1979) A fine-grained anatomical analysis of the role of the rat suprachiasmatic nucleus in circadian rhythms of feeding and drinking. J. Comp. Neurol. 160: 307-326.