Neurosurgery
P.O., Box 208082
New Haven, CT 06520-8082
Tel: 203.785.2805
Fax: 203.785.6916
neurosurgery@yale.edu
Our research group is interested in characterizing the role of the microenvironment on adult neural stem cells and neurogenesis. More specifically our goal is to identify some of the signaling molecules that are specific to neurogenic niches and control the behavior of neural stem cells and progenitors. We have further expanded our line of research to determine how the neurogenic microenvironment controls the temporal pattern of gene expression in neural stem cells and progenitors. These studies are essential because they provide the first insights into the signaling molecules and communication mechanisms that control the behavior of stem cells and neurogenesis. Furthermore, identification of special neurogenic factors will help design strategies to recruit progenitor cells and restore neurons or glia lost as a result of neurodegenerative diseases. We use state-of-the-art technology combining electrophysiology and imaging with molecular biology at the single cell level.
Please check out our list of recent publications for a more detailed description of our findings.
Angelique Bordey, PhD. in 1995, Strasbourg, France Angélique Bordey at yale.edu Associate Professor, Department of Neurosurgery and Cellular & Molecular Physiology. Member of the Interdepartmental Neuroscience Program (INP) and BBS.
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Last updated
6/30/08
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