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Yale University
School of Medicine
Department of Neurology
P.O. Box 208018
New Haven, CT
06520-8018


Faculty Research Interests

Black, Joel A., Ph.D. Membrane structure in normal and pathological neurons and glia. Ion channel expression in normal and injured neurons. Neuro-glial interactions. Cell biology of neurological disease.
Blumenfeld, Hal, M.D., Ph.D. Combined electrophysiology and neuroimaging. Human functional neuroanatomy. Epilepsy, human studies and animal models, Cortical-subcortical mechanisms of consciousness
Booss, John, M.D. HIV neurology, HIV long term care, and multiple sclerosis.
Bracken, Michael, M.D. Epidemiology of diseases of pregnancy and newborns with an emphasis on environmental and genetic risk factors for causation and iatrogenic factors in patient care.
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Carrithers, Michael, M.D., Ph.D. Neuroimmunology, with a focus on mechanisms of inflammation in the CNS and how the response of the CNS microenvironment dictates specific disease phenotypes. A working hypothesis is that aberrant homing of immune cells to the brain can result in autoimmune disease such as multiple sclerosis.
Dib-Hajj, Sulayman, Ph.D. Molecular biology of voltage-gated sodium channels, quantitative analysis of gene expression in normal and injured neurons, structure-function relationship of sodium channel alpha subunits, identification of proteins that modulate channel properties. Molecular pathophysiology of spinal cord dysfunction and multiple sclerosis.

Duckrow, Robert, M.D.

 
Eisa, Mahmood, M.D. Development and implementation of a model of care for Parkinson's disease patients using performance measures/quality indicators. Currently developing quality indicators for Parkinson's disease management. Also interested in the development of current drug guidelines for use with Parkinson's disease drugs such as Ropinirole, Entacapone, Provigil and Rivastigmine.
Hisama, Fuki M., M.D. Molecular genetic aspects of neurologic diseases. Function of the gene for Werner's syndrome (adult-onset progeria).
Kocsis, Jeffrey D., Ph.D. Pathophysiology of axonal regeneration and demyelination and cellular transplantation. Intracellular Ca2+ signaling mechanisms, ion channel and receptor plasticity in response to injury. Studies on cellular mechanisms of anticonvulsants such as gabapantin and vigabatrin, GABA metabolic modulations.
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Lo, Albert., M.D., Ph.D. Pathobiology of demyelinating disease, neuronal injury and repair, neuroprotection, MS epidemiology, robotic neurorehabilitation, clinical trial design and methodology
Mattson, Richard H., M.D. Epilepsy, antiepileptic drug pharmacology. Intensive EEG monitoring, epilepsy surgery, new antiepileptic drugs. Women and epilepsy.
Ment, Laura R., M.D.
Neonatal intraventricular hemorrhage: prevention and sequelae. Cellular and molecular studies of germinal matric microvascular maturation and the effect of chronic sublethal hypoxia on the developing brain.
Navaratnam, Kumar, M.D., Ph.D.
 
Novella, Steven, M.D. Peripheral neuropathy and clinical neurophysiology. Clinical management of motor neuron disease.
Novotny, Edward J.,Jr., M.D. Pediatric epilepsy. Non-invasive investigation of cerebral metabolism. Neonatal seizures, glucose metabolism in insulin dependent diabetes, and phenylketonuria. Investigation of cerebral metabolism and function by nuclear magnetic resonance spectroscopy. Neurometabolic disorders, metabolism of epilepsy, developmental changes in cerebral metabolism, interrelationship of metabolism, neuronal function and physiology, metabolic regulation of ion channels and amino acid neurotransmitters. Glial-neuronal metabolic interactions.
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Petroff, Ognen A.C., M.D.
Nuclear magnetic resonance spectroscopy and studies of cerebral metabolism. Glutamate and GABA metabolism in epilepsy. In vivo brain pharmacology of antiepileptic drugs. Apparent diffusion coefficient of brain water mapping in epilepsy. Brain water relaxometry MRI in epilepsy. In vivo cerebral metabolism measured by 13C labeled tracers.
Rakic, Pasko, M.D., Ph.D. Cellular events and molecular mechanisms that govern development of the mammalian CNS. Effects of various epigenetic factors on the development of structural, molecular and functional cell phenotypes, and their segregation into topographic maps and synaptic neurotransmitters/receptors architecture in laminated structures (cerebellum, hippocampus, neocortex).
Richerson, George B., M.D., Ph.D.
Effect of PCO2 and pH on ion channel functions. Neural control of breathing, and neurobiological substrates of disorders of breathing. Mechanisms of action on anticonvulsants. Role of seratonin in brain function.
Shaywitz, Bennett A., M.D.
Functional organization of the brain for reading and language using functional magnetic resonance imaging; reading and language related processes: classification/definition of learning and attention disorders.
Spencer, Susan S., M.D.
Localization of epileptic foci, application and interpretation of intracranial EEG, seizure spread patterns, outcome after epilepsy surgery, quality of life measurement and findings in epilepsy and after various treatments.
Strittmatter, Stephen., M.D., Ph.D.

Axonal regeneration and functional neurologic recovery after CNS injury, axon growth inhibitors in adult CNS, signal transduction mechanisms underlying semaphorin-directed neuronal development.
Waxman, Stephen G., M.D., Ph.D. Molecular neurobiology of neurobiological diseases, with emphasis on neural
plasticity, functional recovery, and regeneration. Ion channel organization within normal and injured neurons and glial cells.
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Last Modified: Jan 2007



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