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Yale Microarray Database
(YMD)
Janet Hager, Ph.D.
300 George Street
Room 2115
New Haven CT, 06511
Kei-Hoi Cheung, Ph.D.
333 Cedar Street
PO Box 208009
New Haven, CT 06520

Contact Us
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YMD
> Publications
> Publications Utilizing Services and/or Support Provided by the Keck
DNA Microarray Resource
2007
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Su N, He K, Jiao Y, Chen C,
Zhou J, Li L, Bai S, Li X, Deng XW.(2007) Distinct reorganization of the
genome transcription associates with organogenesis of somatic embryo, shoots,
and roots in rice. Plant Mol Biol. 63:337-349
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Zhou J, Wang X, Jiao Y, Qin
Y, Liu X, He K, Chen C, Ma L, Wang J, Xiong L, Zhang Q, Fan L, Deng XW. Global
genome expression analysis of rice in response to drought and high-salinity
stresses in shoot, flag leaf, and panicle. Plant Mol Biol. 2007 Jan 16; [Epub
ahead of print]
2006
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Zhang SS, Xu X, Liu MG,
Zhao H, Soares MB, Barnstable CJ, Fu XY.(2006) A biphasic pattern of gene
expression during mouse retina development. BMC Dev Biol.6(48)
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Johung K, Goodwin EC,
Dimaio D. Human papillomavirus E7 repression initiates a transcriptional
cascade driven by the retinoblastoma family in senescing cervical carcinoma
cells. J Virol. 2006 Dec 20; [Epub ahead of print]
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Chimge NO, Mungunsukh O,
Ruddle F, Bayarsaihan D. Gene expression analysis of TFII-I modulated genes in
mouse embryonic fibroblasts. J Exp Zoolog B Mol Dev Evol. 2006 Nov 8; [Epub
ahead of print]
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Patterson, T.A., Lobenhofer,
E.K., Fulmer-Smentek, S.B., Collins, P., Chu, T-M., Bao, W., Fang, H.,
Kawasaki, E.S., Hager, J., Tikhonova, I.R., Walker, S.J., Zhang, L., Hurban,
P., de Longueville, F., Fuscoe, J.C., Tong, W., Shi, L., and Wolfinger, R.D.
(2006) Performance Comparison of One-Color and Two-Color Platforms Within the
Microarray Quality Control (MAQC) Project. Nature Biotechnology.24(9),
1140-50.
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Shi, L. et al., MAQC
Consortium. (2006) The MicroArray Quality Control (MAQC) project shows
interplatform reproducibility of gene expression measurements. Nature
Biotechnology, 24(9):1151-1161
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Hager, J., (2006) Making
and using spotted DNA Microarrays in an academic core laboratory In Methods in
Enzymology Vol. 41 0: DNA Microarrays Part A: Array Platforms and Wet-Bench
Protocols. (Kimmel, A.and Oliver, B. eds) Elsevier, San Diego, CA, in press.
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Lei H, Juan AH, Kim MS,
Ruddle FH. (2006) Identification of a Hoxc8-regulated transcriptional network
in mouse embryo fibroblast cells. Proc Natl Acad Sci U S A. 103(27):10305-9.
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Kim, K., Page, G.P.,
Beasley, T.M., Barnes, S., Scheirer, K.E., and Allison, D.B. (2006) A proposed
metric for assessing the measurement quality of individual microarrays. BMC
Bioinformatics. 7(1), 35.
2005
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Hunsberger, J.G., Bennett,
A.H., Selvanayagam, E., Duman, R.S., and Newton, S.S. (2005) Gene profiling
the response to kainic acid induced seizures. Brain Res Mol Brain Res. 141
(1):95-112.
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Ma, L., Chen, C., Liu, X.,
Jiao, Y., Su, N., Li, L., Wang, X., Caa, M., Sun, N., Zhang, X., Bao, J., Li,
J., Pedersen, S., Bolund, L., Zhao, H., Yuan, L., Wong, G.K., Wang, J., Deng,
X.W., and Wang, J. (2005) A microarray analysis of the rice transcriptome and
its comparison to Arabidopsis. Genome Res. 15(9),1274-1 283.
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Lei, H., Wang, H., Juan,
A.H., and Ruddle, F.H. (2005) The identification of Hoxc8 target genes. Proc
Natl Acad Sci U S A., 102(7), 2420-4.
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Kluger, H.M., Lev, D.C.,
Kluger, Y., McCarthy, M.M., Kiriakova, G., Camp, R.L., Rimm, D.L., and Price,
J.E. (2005) Using a Xenograft Model of Human Breast Cancer Metastasis to Find
Genes Associated with Clinically Aggressive Disease. Cancer Res., 65(13),
5578-5587.
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Cook, H.L., Lytle, J.R.,
Mischo, H.E., Li, M.J., Rossi, J.J., Silva, D.P., Desrosiers, R.C., and Steitz,
J.A. (2005) Small nuclear RNAs encoded by Herpesvirus saimiri upregulate the
expression of genes linked to T cell activation in virally transformed T
cells. Curr Biol., 15(10), 974-9.
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Newton, S.S., Bennett, A.,
and Duman, R.S. (2005) Production of custom microarrays for neuroscience
research. Methods 37(3), 238-246.
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Ma, L., Sun, N., Liu, X.,
Jiao, Y., Zhao, H., and Deng, X.W. (2005) Organ-specific expression of
Arabidopsis genome during development. Plant Physiol., 138(1), 80-91.
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Feng, J.X., Liu, D., Pan,
Y., Gong, W., Ma, L.G., Luo, J.C., Deng, X.W., and Zhu, Y.X. (2005) An
annotation update via cDNA sequence analysis and comprehensive profiling of
developmental, hormonal or environmental responsiveness of the Arabidopsis
AP2JEREBP transcription factor gene family. Plant Mol Biol., 59(6), 853-868.
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Jiao, Y., Ma, L.,
Strickland, E., and Deng, X.W. (2005) Conservation and divergence of
light-regulated genome expression patterns during seedling development in rice
and Arabidopsis. Plant Cell, 17(12), 3239-3256.
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Yatsula B, Lin S, Read A,
Poholek A, Yates K, Yue D, Hui P, Perkins A. (2005) Identification of binding
sites of EVI1 in mammalian cells. J. Biol Chem. (In Press).
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Amin DN, Tuck D, Stern DF.
(2005) Neuregulin-regulated gene expression in mammary carcinoma cells. Exp
Cell Res. Jun 15; [Epub ahead of print]
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Grau M, Sole X, Obrador A,
Tarafa G, Vandrell E, Valls J, Moreno V, Peinado MA, Capella G. (2005)
Validation of RNA Arbrirarily Primed PCR Probes Hybridized to Glass cDNA
Microarrays: Application to the analysis of limited samples. Clin Chem. 51(1):
93-101.
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Zhang SS, Xu X, Li J, Liu
MG, Zhao H, Soares MB, Barnstable CJ, Fu XY. (2005) Comprehensive in silico
functional specification of mouse retina transcripts. BMC Genomics. 6(1):40.
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Zhang WK, Shen YG, He XJ,
Du BX, Xie ZM, Luo GZ, Zhang JS, Chen SY. (2005) Characterization of a novel
cell cycle-related gene from Arabidopsis. J Exp Bot. 56(413):807-16.
2004
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Khil PP, Smirnova NA,
Romanienko PJ, Camerini-Otero RD. (2004) The mouse X chromosome is enriched
for sex-biased genes not subject to selection by meiotic sex chromosome
inactivation. Nat Genet. 36(6):642-6.
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Amin DN, Perkins AS, Stern
DF. (2004) Gene expression profiling of ErbB receptor and ligand-dependent
transcription. Oncogene. 23(7):1428-38.
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Kluger, H.M., Kluger, Y.,
Gilmore-Hebert, M., Chang, J., Rodov, S., Mironenko, O., Kacinski, B.,
Perkins, A., and Eva Sapi. (2004) cDNA Microarray Analysis of Invasive and
Tumorigenic Phenotypes in a Breast Cancer Model. Lab Invest. 84(3):320-31.
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Chen, J., Newton, S.S.,
Zeng, L., Adams, D.H., Dow, A.L. Madsen, M., Nestler, E.J., and Duman, R.S.
(2004) Downregulation of the CCAAT-enhancer binding protein beta in deltaFosB
transgenic mice and by electroconvulsive seizures. Neuropsychopharmacology,
29(1): 23-31
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Ueland, J.M., Gwira, J.,
Lui, ZX and Cantley, L.G. (2004) The chemokine KC regulates HGF-stimulated
epithelial cell morphogenesis. Am J Physiol Renal Physiol. 286(3): F581-9.
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Cook, H.L, Mischo, H.E. and
Steitz, J.A. (2004) The Herpesvirus saimiri small nuclear RNAs recruit AU-rich
element-binding proteins but do not alter host AU-rich element-containing mRNA
levels in virally transformed T cells. Mol Cell Biol. 2004 24(10):4522-33.
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Cheung, K.H., Hager, J.,
Pan, D., Srivastava, R., Mane, S., Li, Y., Miller, P., Williams, K. (2004)
KARMA: A web server application for comparing and annotating heterogeneous
microarray platforms. Nucleic Acids Research 32(Web Server issue):W441-W444.
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Torpey N, Maher SE,
Bothwell AL, Pober JS. (2004) Interferon alpha but not interleukin 12
activates STAT4 signaling in human vascular endothelial cells. J Biol Chem.
279(25):26789-96.
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Wu Y, Zhang X, Bardag-Gorce
F, Robel RC, Aguilo J, Chen L, Zeng Y, Hwang K, French SW, Lu SC, Wan YJ.
(2004) Retinoid X receptor alpha regulates glutathione homeostasis and
xenobiotic detoxification processes in mouse liver. Mol Pharmacol.
65(3):550-7.
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Hoek, K., Rimm, D. L.,
Williams, K. R., Zhao, H., Ariyan, S., Lin, A., Kluger, H. M., Berger, A. J.,
Cheng, E., E. Trombetta, S., Wu, T., Niinobe, M., Yoshikawa, K., Hannigan, G.
E., and Halaban, R. Expression profiling reveals novel pathways in the
transformation of melanocytes to melanomas. Cancer Res., 64: in press, 2004. (Suppl.
material)
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Khil PP, Smirnova NA,
Romanienko PJ, Camerini-Otero RD. (2004) The mouse X chromosome is enriched
for sex-biased genes not subject to selection by meiotic sex chromosome
inactivation. Nat Genet. 36(6):642-6.
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Zhou D, Xue J, Gavrialov O,
Haddad GG. (2004) Na+/H+ exchanger 1 deficiency alters gene expression in
mouse brain. Physiol Genomics. 18(3):331-9.
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Cheung, K.H., de Knikker,
R., Guo, Y., Zhong G., Hager, J., Yip, K.Y., Kwan,A.K.H., Li, P. and Cheung,
D.W. (2004) Biosphere: the interoperation of web services in microarray
cluster analysis. Applied Bioinformatics (In Press).
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Tangir J, Bonafe N,
Gilmore-Hebert M, Henegariu O, Chambers SK. (2004) SGK1, a potential regulator
of c-fms related breast cancer aggressiveness. Clin Exp Metastasis.
21(6):477-83.
2003
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Zik, M., and Irish, V.F. (2003) Global Identification of Target Genes
Regulated by APETALA3 and PISTILLATA Floral Homeotic Gene Action, The Plant
Cell 15, 1–17.
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Ma, L., Zhao, H., and Deng, X. (2003) Analysis of the mutational effects of
the COP/DET/FUS loci on genome expression profiles reveals their overlapping
yet not identical roles in regulating Arabidopsis seedling development. Genes
and Development, 130, 969-981.
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Lage, J., Leamon, J., Pejovic, T., Hamann, S., Lacey, M., Dillon, D., Segraves,
R., Vossbrinck, B., González, A., Pinkel, D., Albertson, D.G., Costa, J., and
Lizardi, P.M. (2003) Whole genome analysis of genetic alterations in small DNA
samples using hyperbranched strand displacement amplification and array-CGH.
Genome Research 13, 294-307.
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Savaldi-Goldstein, S., Aviv, D, Davydov, O., Fluhr, R. (2003) Alternative
Splicing Modulation by a LAMMER Kinase Impinges on Developmental and
Transcriptome Expression. Plant Cell. 15(4), 926-38.
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Feng, S., Ma, L.G., Wang, X, Xie, D., Dinesh-Kumar, S. P., Wei, N, and Deng,
X.W. (2003) The COP9 Signalosome Physically Interacts with SCFCOI1 and
Modulates Jasmonate Responses. The Plant Cell. 15(5): 1083-94.
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Wu, P, Ma, L.G., Hou, X, Liu, F, Deng, X.W. (2003) Phosphate Starvation Signal
in Roots Triggers a Global Alteration of Cellular Metabolism and Genome
Expression in Arabidopsis. Plant Physiology. 132(3): 1260-71
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Page, G. P., Edwards, J. W., Barnes, S., Weindruch, R., Allison, D. B. (2003)
A Design & Statistical Perspective on Microarray Gene Expression Studies in
Nutrition: The Need for Playful Creativity and Scientific Hard-Mindedness.
Nutrition 19(11-12):997-1000.
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Gadbury, G. L., Page, G. P., Heo, M., Mountz, J. D., & Allison, D. B. (2003)
Randomization tests for small samples: An application for genetic expression
data. Journal of the Royal Statistical Society, Series C (Applied Statistics)
in press.
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Li, M., Zhang, S.S., and Barnstable, C.J. (2003) Developmental and tissue
expression patterns of mouse Mpp4 gene. Biochem Biophys Res Commun. 2003 Jul
25;307(2):229-35.
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Guda K, Cui H, Garg S, Dong M, Nambiar PR, Achenie LE, Rosenberg DW. (2003)
Multistage gene expression profiling in a differentially susceptible mouse
colon cancer model. Cancer Lett. 28; 191(1):17-25.
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Guda K, Claffey KP, Dong M, Nambiar PR, Rosenberg DW. (2003) Defective
processing of the transforming growth factor-beta1 in azoxymethane-induced
mouse colon tumors. Mol Carcinog. 37(1): 51-9.
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Sun N, Ma L, Pan D, Zhao H and Deng X-W. (2003) Evaluation of light regulatory
potential of Calvin cycle steps based onlarge-scale gene expression profiling
data. Plant Molecular Biology 53: 467–478.
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Bais HP, Vepachedu R,
Gilroy S, Callaway RM, Vivanco JM. (2003) Allelopathy and exotic plant
invasion: from molecules and genes to species interactions. Science.
5;301(5638):1377-80.
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Sun N, Ma L, Pan D, Zhao H
and Deng X-W. (2003) Evaluation of light regulatory potential of Calvin cycle
steps based on large-scale gene expression profiling data. Plant Molecular
Biology 53: 467–478.
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Weitzel JM, Hamann S, Jauk
M, Lacey M, Filbry A, Radtke C, Iwen KA, Kutz S, Harneit A, Lizardi PM, Seitz
HJ. (2003) Hepatic gene expression patterns in thyroid hormone-treated
hypothyroid rats. J Mol Endocrinol. 31(2):291-303.
2002
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Wisnewski, A.V., Liu, Q.,
Miller, J.J., Magoski, N., Redlich, C.A. (2002) Effects of Hexamethylene
Diisocyanate Exposure on Human Airway Epithelial Cells: In Vitro Cellular and
Molecular Studies. Environmental Health Perspectives 110 (9) 901-907.
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Lage, J.M., Hamann, S.,
Gribanov, O., Leamon, J.H., Pejovic, T., Lizardi, P.M. (2002) Microgel
assessment of nucleic acid integrity and labeling quality in microarray
experiments. Biotechniques; 32(2), 312-4.
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Ma, X., Husain, T., Peng,
H., Lin, S., Mironenko, O., Maun, N., Johnson, S., Tuck, D., Berliner, N.,
Krause, D.S., and Perkins, A.S. (2002) Development of a murine hematopoietic
progenitor cDNA microarray using a subtracted cDNA library. Blood; 100(3):
833-844.
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Wang, H., Ma, L., Habashi,
J., Li, J., Zhao, H., and Deng, X. W. (2002) Analysis of far-red
light-regulated genome expression profiles of phytochrome A pathway mutants in
Arabidopsis. The Plant Journal 32, 723-733.
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Ma, L., Gao, Y., Qu, L.,
Chen, Z., Li, J., Zhao, H., and Deng, X.W. (2002) Genomic Evidence for COP1 as
a Repressor of Light-Regulated Gene Expression and Development in Arabidopsis.
The Plant Cell 14, 2383–2398.
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Cheung, K.H., White, K.,
Hager, J., Gerstein, M., Reinke, V., Nelson, K., Masiar, P., Srivastava, P.,
Li, Y., Li, J., Li, J.M., Allison, D.B., Snyder, M., Miller, P., Williams, K.
(2002) YMD: A microarray database for large-scale gene expression analysis.
Proceedings of the American Medical Informatics Association 2002 Annual
Symposium, 140-144.
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Allison, D.B., and Coffey,
C.S. (2002) Two-Stage Testing in Microarray Analysis: What is Gained? Journal
of Gerontology, Biological Sciences; 57(5), 189-92.
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Allison, D. B., Gadbury,
G., Heo, M, Fernandez, J, Lee, C-K, Prolla, T. A., & Weindruch, R. (2002). A
Mixture Model Approach For The Analysis Of Microarray Gene Expression Data.
Computational Statistics & Data Analysis, 39, 1-20.
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Allison, D. B. (2002),
Statistical Methods For Microarray Research For Drug Target Identification,
2002 Proceedings of the American Statistical Association, Biopharmaceutical
Section [CD-ROM], Alexandria, VA: American Statistical Association.
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Cheung, K.H., Hager, J.,
Nelson, K., White, K., Li, Y., Snyder, M., Williams, K., Miller, P. (2002) A
dynamic approach to mapping coordinates between microplates and microarrays.,
J Biomed Inform. 35(5-6):306-12.
2001
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Ladner, D.P., Leamon, J.H.,
Hamann, S., Tarafa, G., Strugnell, T., Dillon, D., Lizardi, P., and Costa, J.
(2001) Multiplex Detection of Hotspot Mutations by Rolling Circle-Enabled
Universal Microarrays. Laboratory Investigation; 81:1079-1086.
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Wang, H., Ma, L., Li, J.,
Zhao, H., Deng, X. (2001) Direct Interaction of Arabidopsis Cryptochromes with
COP1 in Light Control Development. Science; 294:154-158.
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Luo, C., Shent, B., Manley,
J.l., and Zheng, L. (2001) Tehao functions in the Toll pathway in Drosophilia
melanogaster: possible roles in development and innate immunity. Insect
Molecular Biology; 10(5):457-464.
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Ma, L., Li, J., Qu, L.,
Hager, J., Chen, Z., Zhao, H., Deng, X. (2001) Light control of Arabidopsis
development entails coordinated regulation of genome expression and cellular
pathways. Plant Cell; 13, 2589-2607.
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