Susan Baserga, MD, PhD

Susan Baserga
Professor of Molecular Biophysics & Biochemistry, Genetics, and Therapeutic Radiology

B.S. Yale College 1980
M. Phil. Yale University 1984
M.D., Ph.D. Yale University 1988

Research Interests

Control of cell growth by pre-rRNA processing and ribosome assembly in eukaryotes

Representative Publications

Dragon, F., Gallagher, J.E.G., Compagnone-Post, P.A., Mitchell, B.M., Porwancher, K.A., Wehner, K.A., Wormsley, S., Settlage, R.E., Shabanowitz, J., Osheim, Y., Beyer, A.L., Hunt, D.F. and Baserga, S.J. A large nucleolar U3 ribonucleoprotein required for 18S rRNA biogenesis. Nature 417:967-970 (2002). Commentary in Chemistry and Biology (9, 777-780, 2002) and Current Biology (12, R623-R624, 2002).

Gallagher, J.E., Dunbar, D.A., Granneman, S., Mitchell, B.M., Osheim, Y., Beyer, A.L. and Baserga, S.J. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes and Development 18:2506-2517 (2004).

Bernstein, K.A. and Baserga, S.J. The SSU processome is required for cell cycle progression at G1. Molecular Biology of the Cell 15: 5038-5046 (2004).