sung (2K)
Department of Molecular Biophysics and Biochemistry
Yale University

333 Cedar Street, PO Box 208024
New Haven, CT 06520-8024
Phone Number (203) 785-4569

publicationimage (4K)
(selected from 87 published)
Sung, P. (1994) Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein. Science 265:1241-1243.
Sung, P. and D. L. Robberson. (1995) DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA. Cell 82:453-461.
Sung, P. (1997) Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes & Develop.11:1111-1121.
Sung, P. (1997) Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase. J. Biol. Chem. Communication 272:28194-28197.
Petukhova, G. S. Stratton, and P. Sung. (1998) Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins. Nature 393: 91-94
Petukhova, G., P. Sung, and H. Klein (2000) Promotion of Rad51-dependent D-loop Formation by Recombination Factor Rdh54/Tid1. Genes & Develop. 614:2206-2215
Van Komen, S., G. Petukhova, S. Sigurdsson, S. Stratton, and P. Sung. (2000) Superhelicity-driven homologous DNA pairing by yeast recombination factors Rad51 and Rad54. Molecular Cell 6:563-572.
Sigurdsson, S., K. Trujillo, B. Song, S. Stratton, and P. Sung. (2001) Basis for avid homologous DNA strand exchange by human Rad51 and RPA. J. Biol. Chem. 276:8798-8806.
#Chen, L., #K. Trujillo, W. Ramos, P. Sung, and A. E. Tomkinson. (2001) Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Molecular Cell, 8:1105-1115. #These two authors contributed equally.
Sigurdsson, S., S. Van Komen, W. Bussen, D. Schild., J. S. Albala, and P. Sung. (2001) Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. Genes & Develop. 15:3308-3318.
*Krejci, L., *S. Van Komen, Y. Li, J. Villemain, M. S. Reddy, H. Klein, T. Ellenberger, and P. Sung. (2003) DNA helicase Srs2 helicase disrupts the Rad51 presynaptic filament. Nature, 423:305-309. *These two authors contributed equally.
Featured in Nature News & Views "Disruptive Influence" by Marco Foiani, (2003), 423:234-235.
Highlighted in Nature Reviews Molecular Cell Biology "Timely Interruption" by Arianne Heinrichs (2003), 4:423.
Wolner, B., S. Van Komen, P. Sung, C. Peterson. (2003) Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Molecular Cell 12: 221-232.
Sung, P., L. Krejci, S. Van Komen, and M. G. Sehorn. (2003) Rad51 recombinase and recombination mediators. . J. Biol. Chem. 278:42729-42732.