|
|
 |
|
|
|
| |
Human
Megakaryocytopoiesis in Immunodeficient Mice |
| |
|
|
| |
 |
Platelet Flow |
| |
|
 |
| |
|
|
| |
|
Human Platelet Activation |
| |
|
 |
| |
|
Shown above is in
vitro activation of human platelets that developed in immunodeficient
mice following transplantation of CD34 selected G-CSF-mobilized
peripheral blood mononuclear cells. CD62 (P-selectin or platelet
activation dependent granule-external membrane protein, PADGEM)
is expressed on activated, but not quiescent platelets. The
antibody used binds to human CD62 and not to murine CD62. |
| |
|
| |
Research
Papers Available in PDF Format |
| |
|
|
| |
|
Perez L, Rinder
HM, Wang C, Tracey JB, Maun N, Krause DS. Xenotransplantation
of immunodeficient mice with human CD34+ cells provides an in-vivo
model for human megakaryocytopoiesis and platelet production.
Blood 97, 1635-43, 2001. Full
text PDF. |
|
| |
|
| ©2001-2005 Department of Laboratory Medicine, Yale School of Medicine. |
|
|
