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John Booss, MD
Professor of Neurology & Laboratory Medicine

V.A. Medical Center
950 Campbell Ave.
West Haven, CT 06516
932-5711, X3544
john.booss@yale.edu

1961, A.B., Oberlin College
1965, M.D., Albany Medical College
Fellowship: 1969-1971 Yale University; 1973-1975 Jefferson Medical College

Research Interests
My research and clinical work has focused on viral infections, immune responses, and host viral interactions in the nervous system. Previous work from our laboratory has focused on the immune response in the nervous system in multiple sclerosis, a rodent model for cytomegalovirus encephalitis, and the host defense response in the brain to xenogenic allograft. Previous clinical work has focused on viral encephalitis, multiple sclerosis, and HIV neurology.

Present research centers on the evaluation and treatment of neurological complications of HIV infection and the evaluation of immunotherapy in multiple sclerosis. We are part of a multi- institutional national consortium for neuro-AIDS research and are part of a VHA HSR&D study of the therapy of multiple sclerosis.

1. Hall C, Timpone J, Dafni I, Antonijevic Z, Millar L, Booss J, Clifford D, Cohen B, McArthur J, Hollander H & ACTG 243 Team. ARA-C Treatment of PML in AIDS Patients. Abstracts of the Fourth Conference on Retroviruses, p. 66, Washington, DC, January 22-26, 1997.
   
2. Cook SD, Troiano R, Guarnaccia J, Bansil S, Sheffet A, Jotkowitz A, Dowling P, Volmer T, Devereux C, Wolansky L, Haffty B, Goldstein J, Zito G, Booss J, Rohowsky-Kochan C. Total Lymphoid Irradiation and Low Dose Corticosteroids in Progressive MS. J Neurol Sci, in press, 1997.