Case Study#6   1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16   Coagulation Factor Levels   Normal Levels   Factor II 68 % 50-150 %     Factor V 124 % 50-160 %     Factor X 4 % 50-160 % Interp: factor X deficiency. No evidence for vitamin K deficiency or rodenticide ingestion Clinical Course - day 1 Received 1U PRBC 1h into admission 4 units FFP given immediately after diagnosis of factor X deficiency Started on Premarin Hct rose to 23.5% within 12 hrs   Clinical Course - days 2-4 One additional unit of PRBCs Received 2 units FFP/day Factor X levels rose to >20% Menstrual bleeding stopped Premarin D/C'd, started on Lo/Ovral   Discharge plan Followup in Hematology Clinic Continue Lo/Ovral Resume normal activity but no contact sports Avoid NSAIDs and aspirin The great-aunt with the blood disorder was eventually contacted; she too has factor X deficiency