The United States and Canadian Academy of Pathology Lippincott Williams and Wilkins publishes Laboratory Investigation

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			Cover: Composite overlay consisting of a transmission electron micrograph (blue image) and confocal scanning laser microscopy Z-plane sections of T cells transmigrating through endothelial cell monolayers resting on Biocoat cell culture inserts coated with type IV collagen. The upper color image illustrates T cells (green fluorescence) adherent to and migrating through the endothelial cell monolayer (red fluorescence) to the underside of the membrane. The lower color image illustrates the effect of inhibition of the activity of matrix metalloproteinase-2, which is manifested by an arrest of the T cells beneath the endothelial cell layer and above the type IV collagen-coated membrane. See article by Graesser et al.
		INTEGRINS, PROTEINASES, AND EAE: EXPLAINING A COMPLEX WEB OF INTERACTIONS (Graesser et al) THE HEPATOCYTE­MATRIX INTERFACE: A RECEPTIVE ENVIRONMENT? (Schmoelzl et al) DO MAST CELLS CAUSE FIBROSIS? (Okazaki et al) WATCHING CLONES EVOLVE: (see Tang et al)
		Expression of the P2Y6 Purinergic Receptor in Human T Cells Infiltrating Inflammatory Bowel Disease Gino R. Somers, Fleur M. A. Hammet, Lynne Trute, Melissa C. Southey, and Deon J. Venter Analysis of Blood Vessel Maturation Processes during Cyclic Ovarian Angiogenesis Valentin Goede, Tobias Schmidt, Sarah Kimmina, Detlef Kozian, and Hellmut G. Augustin Hepatocyte Growth Factor Is a Potent Trigger of Neutrophil Adhesion through Rapid Activation of Lymphocyte Function-Associated Antigen-1 Shinichiro Mine, Yoshiya Tanaka, Makoto Suematu, Megumi Aso, Takeshi Fujisaki, Shinwa Yamada, and Sumiya Eto Expression of Hepatocyte Low-Density Lipoprotein Receptor-Related Protein Is Post-Transcriptionally Regulated by Extracellular Matrix Sabine Schmoelzl, Sally J. Benn, James E. Laithwaite, Spencer J. Greenwood, W. Sean Marshall, Neil A. Munday, David J. FitzGerald, and Jonathan LaMarre Vitamin E Prevents Apoptosis in Cortical Neurons during Hypoxia and Oxygen Reperfusion Motoki Tagami, Kazuo Yamagata, Katsumi Ikeda, Yasuo Nara, Hideaki Fujino, Akiyoshi Kubota, Fujio Numano, and Yukio Yamori Increase of Mast Cells in the Liver and Lung May Be Associated with but Not a Cause of Fibrosis: Demonstration Using Mast Cell-Deficient Ws/Ws Rats Toshihiko Okazaki, Seiichi Hirota, Zu-de Xu, Kazutaka Maeyama, Akihiro Nakama, Sunao Kawano, Masatsugu Hori, and Yukihiko Kitamura BAX Somatic Frameshift Mutations in Endometrioid Adenocarcinomas of the Endometrium: Evidence for a Tumor Progression Role in Endometrial Carcinomas with Microsatellite Instability Lluis Catasus, Xavier Matias-Guiu, Pilar Machin, Josefina Munoz, and Jaime Prat The Interrelationship of [alpha]4 Integrin and Matrix Metalloproteinase-2 in the Pathogenesis of Experimental Autoimmune Encephalomyelitis Donnasue Graesser, Sepi Mahooti, Tara Haas, Sandra Davis, Robert B. Clark, and Joseph A. Madri Progression of Spontaneous Lymphomas in SJL Mice: Monitoring In Vivo Clonal Evolution with Molecular Markers in Sequential Splenic Samples Johnny C. O. Tang, Faith C. S. Ho, Alexander C. L. Chan, Eva Y. W. Chow, and Gopesh Srivastava
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			Modulation of the Myocardial Response to Ischemia L. Maximilian Buja
			Duct Formation by Immortalized Mouse Cholangiocytes: An In Vitro Model for Cholangiopathies Yutaka Mano, Motoyasu Ishii, Norihiro Kisara, Yoshie Kobayashi, Yoshiyuki Ueno, Koju Kobayashi, Hirofumi Hamada, and Takayoshi Toyota A Simplified Method for the Isolation and Culture of Endothelial Cells from Pseudointima of Transjugular Intrahepatic Portasystemic Shunts Arun J. Sanyal and Faridoddin Mirshahi
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