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Cover:
Upper left, Transgenic mice fed a normal diet had bilateral thyroid
carcinomas characterized by numerous areas of hypercellularity and several
large, irregular, systic tumor follocles.
Upper right, Higher magnification of upper left figure shows follicles lined
by multiple layers of cuboidal to columnar neoplastic follicular cells.
Bottom left, Transgenic mice fed a low-iodine diet had large tumors with
increased cullularity and more extensive extracapsular invasion.
Bottom right, Higher magnification of bottom left figure shows solid epithelioid
and disorganized spidle-cell areas adjacent to regions with conspicuous
follocle formation.
See article by Sagartz et al. |
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- Thyroid-Stimulating Hormone Promotes Growth of
Thyroid Carcinomas in Transgenic Mice with Targeted Expression of the
ret/PTC1 Oncogene John E. Sagartz,
Sissy M. Jhiang, Qiang Tong, and Charles C. Capen
- A Physiologic Function for Alkaline Phosphatase:
Endotoxin Detoxification Klaas
Poelstra, Winston W. Bakker, Pieter A. Klok, Machiel J. Hardonk, and
Dirk K. F. Meijer
- Direct Effects of Somatostatin Analog Octreotide
on Insulin-Like Growth Factor-I in the Arterial Wall
Koshi Yumi, James A. Fagin, Makoto Yamashita, Michael C. Fishbein, Prediman
K. Shah, Sanjay Kaul, Wen Niu, Jan Nilsson, and Bojan Cercek
- Scatter Factor Stimulates Tumor Growth and Tumor
Angiogenesis in Human Breast Cancers in the Mammary Fat Pads of Nude
Mice Katrin Lamszus, Liang Jin,
Alexander Fuchs, Eric Shi, Soheli Chowdhury, Yan Yao, Peter J. Polverini,
John Laterra, Itzhak D. Goldberg, and Eliot M. Rosen
- Experimental Autoimmune Encephalomyelitis: The
Antigen Specificity of T Lymphocytes Determines the Topography of Lesions
in the Central and Peripheral Nervous System
Thomas Berger, Susanne Weerth, Kimikazu Kojima, Christopher Linington,
Hartmut Wekerle, and Hans Lassmann
- Quantitative Immunohistochemical Determination
of 8-Hydroxy-2'-Deoxyguanosine by a Monoclonal Antibody N45.1: Its Application
to Ferric Nitrilotriacetate-Induced Renal Carcinogenesis Model
Shinya Toyokuni, Tomoyuki Tanaka, Yukari Hattori, Yasuyuki Nishiyama,
Atsushi Yoshida, Koji Uchida, Hiroshi Hiai, Hirotomo Ochi, and Toshihiko
Osawa
- Prevention of Endotoxemia-Induced Acute Respiratory
Distress Syndrome-Like Lung Injury in Rabbits by a Monoclonal Antibody
to IL-8 Kenji Yokoi, Naofumi
Mukaida, Akihisa Harada, Yoh Watanabe, and Kouji Matsushima
- Role of Cytokines in the Early Stages of Chronic
Colitis in TCRa-Mutant Mice
Emiko Mizoguchi, Atsushi Mizoguchi, and Atul K. Bhan
- Macrophage Inflammatory Protein-1a (LD78) Expressed
in Human Bone Marrow: Its Role in Regulation of Hematopoiesis and Osteoclast
Recruitment Toshio Kukita, Hisayuki
Nomiyama, Yasukazu Ohmoto, Akiko Kukita, Toshihide Shuto, Takao Hotokebuchi,
Yoichi Sugioka, Retsu Miura, and Tadahiko Iijima
- Genetic Evidence for the Multicentric Origin
of Synchronous Multiple Gastric Carcinoma
Gyeong Hoon Kang, Chong Jai Kim, Woo Ho Kim, Yun Kyung Kang, Hyun Ok
Kim, and Yong Il Kim
- Brca1 is Expressed Independently of Hormonal
Stimulation in the Mouse Ovary
Katherine W. Phillips, Susan M. Goldsworthy, L. Michelle Bennett, Heather
A. Brownlee, Roger W. Wiseman, and Barbara J. Davis
- Establishment of Three Monoclonal Antibodies
Specific for Prespermatogonia and Intratubular Malignant Germ Cells
in Humans Nobuyoshi Hiraoka,
Taketo Yamada, Hitoshi Abe, and Jun-ichi Hata
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