Adminstrative Core
Molecular Core
Physiology Core
Cell Core
Featured Investigator
Directory of Core Members
Pilot & Feasibility Program
CENTER NEWS
MISSION STATEMENT

The Yale Core Center for Musculoskeletal Disorders is dedicated to fostering research in disorders of skeletal tissue and muscle, with the ultimate goal of improving human health. The Center is particularly interested in supporting the development and comprehensive investigation of animal models of musculoskeletal disorders. Investigators whose interests include cellular models of disease, the investigation of novel physiologic pathways or therapeutic interventions are also welcome. To encourage and sustain these efforts, the Center has established core laboratories with expertise in whole-animal and skeletal-tissue analysis, molecular methods and bone-cell culture. The Center also sponsors a seminar series to highlight research by Core members and a pilot project program that will provide scientific, technical and financial support to investigators whose work is relevant to the Center's mission.

SPECIAL MESSAGE FROM THE DIRECTOR

Since there are now five P30 Core Centers funded by NIAMS, all focused on skeletal disease and each with a Pilot & Feasibility program, we thought it would be useful to put together a short workshop on current methods of analysis for skeletal tissue. Many of these methods are not well understood, and yet they are the basic investigative tools of our trade. We therefore organized a half-day symposium in New Haven on Friday, December 14, 2007 for this purpose.

For information and photos on the 2007 Workshop on Skeletal Analysis, please click here: Skeletal Workshop December 14, 2007

Plans for future workshops with Sister Cores are being made. Please be sure to check back periodically.

Additional Links
Endocrine Research
International Bone and Mineral Society
American Society for Bone and Mineral Research
National Osteoporosis Foundation
Orthopaedic Research and Education Foundation

 

 

2009 - 2010
YCCMD Bone Biology Seminar Series

Seminars usually begin at 11:00 am on Thursdays.
Exeptions will be noted.

September 17, 2009
Professor Arthur D. Conigrave, M.D., Ph.D., FRACP
Professor & Head of School
Biochemistry, School of Molecular and Microbial Biosciences
Sydney Medical School
Sydney, Australia

"The role of the calcium-sensing receptor in mediating the
skeletal actions of dietary protein"


October 15, 2009
Jose Luis Millan, Ph.D.
Professor
Sanford Children's Health Research Center
Burnham Institute for Medical Research
La Jolla, CA

"The role phosphatases in skeletal calcification"


November 19, 2009

Ilana Chefetz-Menaker, Ph.D.
Postdoctoral Fellow
Department of Obstetrics & Gynecology
Yale University

"Familial Tumoral Calcinosis:
from the characterization of a rare phenotype to the pathogenesis of ectopic calcification"


December 17, 2009

Thomas L. Clemens, Ph.D.
Professor of Orthopaedic Surgery
Director, Center for Musculoskeletal Research
Johns Hopkins University

"Insulin signaling in bone regulates bone and body composition"


January 21, 2010

Jointly Sponsored by the YCCMD and the
Yale Rheumatic Diseases Center Research Core Center
Laurie H. Glimcher, M.D.
I.H. Given Professor of Immunology
Department of Immunology & Infectious Disease
Harvard School of Public Health

February 18, 2010
To be announced

March 18, 2010
Sundeep Khosla, M.D.
Dr. Francis Chucker & Nathan Landow Research Professor
Departments of Medicine & Physiology, College of Medicine
Mayo Clinic
Rochester, Minnesota

"Title to follow"

April 15, 2010
Annual Research Day

May 20, 2010
Paul Kostenuik


2008-2009

October 16, 2008
Michael Collins, M.D.
Chief, Skeletal Clinical Studies Unit
Craniofacial & Skeletal Diseases Branch
National Institute of Dental & Craniofacial Research, NIH
"New insights into the action and regulation of FGF23"
ROOM: BCMM 206

November 20, 2008
Dwight A. Towler, M.D., Ph.D.
Lang Professor of Medicine
Division of Endocrinology, Metabolism & Lipid Research
Washington University in St. Louis
"
TNFalpha and Msx2-Wnt Signaling in Diabetic Vascular Disease"
Room: BCMM 206

December 18, 2008
Joseph Lorenzo, M.D.
Professor of Medicine, Division of Endocrinology and Metabolism
New England Musculoskeletal Institute
University of Connecticut Health Center

"Studies of the phenotype of osteoclast precursor cells"
Room: BCMM 206

January 29, 2009
Henry J. Donahue, Ph.D.
Baker Professor & Vice Chair for Research
Director, Musculoskeletal Sciences
Department of Orthopaedics & Rehabilitation
Pennsylvania State University College of Medicine
Hershey, PA

"Gap junctions and connexins in
breast cancer metastasis to bone
"
Room: BCMM 206

February 19, 2009
David Goltzman, M.D.
Director, Center for Bone & Periodontal Research
McGill University
Montreal, QC

"Actions of endogenous and exogenous PTH
and PTHrP as anabolic agents in bone"
Room: BCMM 206

March 19, 2009
John S. Adams, M.D.
Vice Chair for Research
Department of Orthopaedic Surgery
UCLA-Orthopaedic Hospital
Los Angeles, CA

"Vitamin D and estrogen action in bone:
A concerted role for hnRNPs in the C family"
Room: BCMM 206

April 16, 2009
Annual Research Day
See Below

May 20, 2009 (Wednesday)
Jointly sponsored by the Yale Core Center in Musculoskeletal
Disorders and in the Yale Rheumatic Diseases Research Core Center
Steven Abramson, M.D.
Professor of Medicine & Pathology
New York University Langone Medical Center
New York, NY

"Pathogenesis of osteoarthritis:
Are there targets for future therapy?"
Room: TAC N-203

June 18, 2009
To be announced
Room: BCMM 206

YCCMD Annual Research Day

April 16, 2009
8:45 am - 12 Noon


Keynote Speakers:

Michael A. Levine, MD, FAAP, FACP, FACE
Division Chief of Endocrinology/Diabetes
The Children's Hospital of Philadelphia
"Gcm2: Master gene for parathyroid development"

Gerard Karsenty, M.D., Ph.D.
Professor and Chair
Genetics and Development
Columbia University
"The novel physiology of bone"

Pilot and Feasibility Project Presentations:

Anton M. Bennett, Ph.D.
Associate Professor
Pharmacology

"Musculoskeletal development by a protein tyrosine phosphatase
through FGF receptor docking protein"

Richard A. Flavell, Ph.D.
Professor & Chair
Immunology

"Regulation of the osteoclastogenesis by IL-1 receptor
and Toll-like receptor signaling"

Click here for more information on Pilot and Feasiblity Projects

Past YCCMD Seminars

 

Yale School of Medicine
Last Edited

01/12/2009 IKS