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CO-DIRECTOR AND CELL CORE DIRECTOR
Mark Horowitz, Ph.D., is a Professor of Orthopaedics and Rehabilitation. Mark has over 20 years of experience in the isolation and characterization of mammalian cells, including more than 15 years of work with bone cells.
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He coordinates the general operations of the Core and ensures that high standards of operation are maintained. He also provides experimental design advice to individual investigators and training in cell isolation and culture to the technical staff and junior faculty.
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General Overview
The main goal of the Cell Core is to facilitate the experimental use of authentic primary isolated mouse and rat osteoblastic cells as well as primary osteoclasts and osteoclast-like cells generated from co-culture.
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Last Edited
July 12,2001 TD
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Core Services
- Isolation and cultivation of primary murine and fetal rat calvarial osteoblasts. This includes large scale preparations for biochemical studies and RNA and DNA purification.
- Cultivation of murine osteoclast-like cells generated from in vitro co-culture.
- Isolation of authentic osteoclasts from rabbits and rats.
- Training in the in vitro isolation and culture of osteoblastic and osteoclastic cells, so that investigators, appropriately trained, can initiate and maintain these cells in their laboratories.
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