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DIRECTOR
Karl Insogna, M.D.  He is a Professor of Medicine in the Department of Medicine (Endocrine), and he has been at Yale for 20 years. He is well known in the field of bone biology, and his research interests range from basic bone cell biology to clinical research in metabolic bone diseases. He is responsible for supervising all the activities of the YCCMD including scientific and administrative affairs. He, together with Dr. Gundberg, manages the Pilot and the Feasibility Studies Program

ADMINISTRATOR
Irene Sherman
Department of Internal Medicine
Section of Endocrinolgy
333 Cedar St. PO Box 208020
New Haven Ct. 06520- 8020
Phone (203) 737-2871
Fax (203) 785-6462
irene.sherman@yale.edu
Yale School of Medicine


CO-DIRECTOR AND CELL CORE DIRECTOR

Mark Horowitz, Ph.D., He is a Professor of Orthopaedics and Rehabilitation, and he has been at Yale for 23 years. He has been interested for nearly two decades in the interactions among the skeletal, hematopoietic and immune systems and is internationally recognized for his work in cytokine biology and signal transduction and its role in bone metabolism.

 
PILOT AND FEASABILITY PROGRAM
Dr. Caren Gundberg, directs the Pilot and Feasability Program. She is a Professor in the Department of Orthopaedics and Rehabilitation and has been at Yale for 14 years. Her research interests focus on osteocalcin, the vitamin K-dependent protein synthesized in bone. She has an international reputation in the development and chemistry of non-invasive measures of bone turnover.

MOLECULAR CORE
William Philbrick, Ph.D., Associate Professor of Medicine and Director of the Molecular Core. He is a molecular and cellular biologist with extensive experience in gene expression systems both in cultured cells and in animal models. Bill has been actively involved in training others in the use of the methodologies offered by the Core for the past 15 years. He currently also serves as the Director of the Molecular Core of the Yale Diabetes Endocrine Research Center.

Last Edited
10/18/2005 JBS

PHYSIOLOGY CORE
Thomas O. Carpenter, M.D.,
is Director of the Physiology Core. He is a pediatric endocrinologist with long-standing interest in vitamin and mineral metabolism. He has investigated the regulation of phosphate homeostasis in humans and other mammalian systems throughout his career, with particular attention to the study of clinical disorders of calcium and phosphate metabolism. He has extensive experience in cell culture studies, as well as both animal and human investigation. He has recently focused attention on magnesium's role in the acquisition of skeletal mass. He has published several important papers on the effects of magnesium depletion on bone mass in experimental animals.