Research

Faculty members are involved in clinical projects focused on issues relevant to rheumatic diseases, with particular interests in Lyme disease and systemic lupus erythematosus (SLE). In addition to our general rheumatology clinics, we have a lupus clinic devoted to the care of patients with SLE and the related diseases of scleroderma, polymyositis, and Sjogren's syndrome.

Linda Bockenstedt, M.D.
Professor of Medicine

Richard Bucala M.D., Ph.D.
Professor of Medicine and Pathology

Joseph Craft, M.D.
Professor of Medicine, Chief of Rheumatology
Professor of Immunobiology and Director of Investigative Medicine

Janine Evans, M.D.
Associate Professor of Medicine

Liana Fraenkel, M.D., MPH., PRCP(C)
Associate Professor of Medicine
Section Chief of Rheumatology, Veteran's Administration

Insoo Kang, M.D.
Rheumatology Program Director
Associate Professor of Medicine

Stephen Malawista, M.D.
Professor of Medicine

Mark Mamula, Ph.D.
Professor of Medicine

Ruth Montgomery, Ph.D.
Senior Research Scientist

Timothy Quan, M.D.
Instructor Internal Medicine

Lisa Gale Suter, M.D.
Assistant Professor of Medicine

Zhinan Yin, M.D., Ph.D.
Adjunct Associate Professor of Medicine

Research training faculty in other departments or sections

Philip W. Askenase, M.D., Professor of Medicine and Pathology

The mechanism(s) of initiation and regulation of T cell mediated reactions in vivo, such as delayed-type hypersensitivity (DTH); how effector T cells are recruited from the intravascular space to cross the endothelial cell barrier and enter the tissues in beneficial immune responses, such as: rejection of tumors, and resistance to microorganisms, and parasites; and also in deleterious responses such as allergy and autoimmunity.

Erol Fikrig, M.D., Professor of Medicine, Epidemiology and Public Health and Microbial Pathogenesis, Section Chief Infectious Diseases

Studies are directed toward understanding Lyme disease, Human granulocytic ehrlichiosis, and West Nile virus.

Richard Flavell, Ph.D., Professor and Chairman of Immunobiology; HHMI Investigator

Use of transgenic and gene-targeted mice to study T-cell tolerance and activation in immunity and autoimmunity. Apoptosis; regulation of T cell differentiation.

Fred S. Kantor, M.D., Paul B. Beeson Professor of Medicine

The current laboratory research focuses on the immune response to Borrelia burgdorferi. We are studying the antigenic variability of the spirochete in the infected host, and delineating the molecular and immunologic basis for immunity against tick bite.

Mark J. Shlomchik, M.D., Ph.D., Professor, Laboratory Medicine & Immunobiology

Regulation and pathogenesis of autoantibody-producing B cells in normal and autoimmune mice; B-cell memory; mechanism of graft vs host/leukemia.

Warren D. Shlomchik, M.D., Associate Professor of Medicine

Allogeneic stem cell transplantation; graft vs. host disease; Allogeneic stem cell transplantation as a curative therapy for malignant diseases, sickle cell anemia and the thalassemias, and perhaps for autoimmune diseases.