H. Klar Yaggi, M.D., M.P.H.

Assistant Professor
Pulmonary and Critical Care Section

Educational Background

Undergraduate: The Johns Hopkins University, Baltimore Maryland
Medical School: University of Maryland School of Medicine, Baltimore Maryland
Residency: Internal Medicine, Yale-New Haven Hospital, New Haven, CT
Fellowship: Pulmonary, Critical Care, and Sleep Medicine, Yale University School of Medicine, New Haven, CT

Clinical Interests

• Sleep Apnea
• Narcolepsy
• Asthma
• Research Interests

As a Sleep Medicine specialist, Dr. Klar Yaggi's research focuses on the clinical epidemiology of sleep-disordered breathing and its relationship to cardiovascular disease, stroke, and cardiovascular disease risk factors. His multidisciplinary research team includes general internists, neurologists, and health services researchers. The team has recently completed an observational cohort study of patients recruited through the Yale Center of Sleep Medicine which demonstrated that obstructive sleep apnea significantly increases the risk for the composite outcome of transient ischemic attack, stroke, and death independent of traditional cardiovascular risk factors. In addition, using the Massachusetts Male Aging Cohort, they investigated the impact of "sleep debt" on the development of overt clinical diabetes. His ongoing work entails constructing a prognostic system to identify patients suspected of sleep-disordered breathing with incrementally increased risk for cardiovascular complications. As a result of these studies, Dr. Yaggi plans to explore the impact treatment of sleep disordered breathing on the primary and secondary prevention of cardiovascular disease and stroke. He is currently funded by a VA Health Services Research and Development Career Development Award

Representative Publications

Yaggi H, Mohsenin V. Obstructive sleep apnea and stroke. Lancet Neurol. 2004;3(6):333-42

Yaggi H, Concato J, Kernan W, Lichtman J, Brass L, Mohsenin V. Obstructive sleep apnea as a risk factor for stroke and death. New England Journal of Medicine. 2005;
353 (19): 2035-2041

Yaggi H, Araujo A, McKinley J. Sleep Duration as Risk Factor for Type 2 Diabetes Mellitus: Diabetes Care 2006; 29(3):657-61.

Contact

Campus Address
Department of Internal Medicine
P.O. Box 208057
New Haven, CT 06520-8057

E-mail
henry.yaggi@yale.edu

Phone
203-785-3207

Fax
203-785-3826

Appointments
203-785-4198