Caroline Seton Loeser, M.D.

Section of Digestive Diseases
more on this physician

Clinical Interests

GERD and extraintestinal manifestations of GERD, Barrett’s esophagus, gastrointestinal cancers, and inflammatory bowel diseas

Research Interests

Endoscopic imaging including confocal endomicroscopy

I am investigating the use of confocal endomicroscopy to identify dysplastic, neoplastic and inflammatory tissue in gastrointestinal diseases. Secondary aims include identification and description of cellular architectural changes that can be detected in vivo as early indicators of progression to dysplasia and neoplasia in order to target tissue and direct biopsies for removal or surveillance. Other goals are to identify molecular markers that predict progression to high-grade dysplasia and neoplasia.

Selected Publications

• Rogart, J.N., Nagata, J., Loeser, C.S., Roorda, R.D., Aslanian, H., Robert, M.E., Zipfel, W.R., and Nathanson, M.H.: Multiphoton imaging can be used for microscopic examination of intact gastrointestinal mucosa. Clinical Gastroenterology and Hepatology, in press
• Loeser CS, Proctor DD. Critical issues in digestive diseases: Gastrointestinal hemorrhage. Pulmonary and Critical Care Update, 2006; volume 20, lesson 8.

Contact

Campus Address
Department of Internal Medicine
333 Cedar Street (LMP 1080)
New Haven, CT 06520

E-mail
caroline.loeser@yale.edu

Office Phone
(203) 785-3390

Appointment Phone
(203) 785-4138