Department of Immunobiology
300 Cedar Street
The Anlyan Center
P.O. Box 208011
New Haven, CT 06520
PROFESSOR OF MEDICINE AND IMMUNOBIOLOGY, ROBERT I. LEVY PROFESSOR OF PREVENTIVE CARDIOLOGY - Defining the cellular and molecular mechanisms which govern leukocyte-endothelial cell (EC) interactions and intercellular adhesion, in the context of cardiovascular disease.
PROFESSOR OF IMMUNOBIOLOGY AND INTERDEPARTMENTAL PROGRAM IN VASCULAR BIOLOGY AND TRANSPLANTATION - Immune responses to vascular interactions in human allo and xeno models; transplant immunobiology; function of murine Ly6 antigens; hematopoietic lineage differentiation.
ASSISTANT PROFESSOR OF IMMUNOBIOLOGY - Chromatin remodeling and gene regulation in the immune system.
PROFESSOR OF MEDICINE AND IMMUNOBIOLOGY, CHIEF OF RHEUMATOLOGY, AND DIRECTOR OF INVESTIGATIVE MEDICINE - Activation, differentiation and effector function of CD4+ T cells in systemic autoimmunity.
PROFESSOR OF IMMUNOBIOLOGY AND CELL BIOLOGY - Molecular mechanisms of antigen processing; assembly and intracellular transport of CD1 molecules, class I and class II MHC molecules; functions and mechanisms of action of interferon-induced proteins.
PROFESSOR AND CHAIRMAN OF IMMUNOBIOLOGY, PROFESSOR OF MOLECULAR, CELLULAR AND DEVELOPMENTAL BIOLOGY - Use of transgenic and gene-targeted mice to study T-cell tolerance and activation in immunity and autoimmunity. Apoptosis; regulation of T cell differentiation.
PROFESSOR OF IMMUNOBIOLOGY, MOLECULAR BIOPHYSICS AND BIOCHEMISTRY, AND MOLECULAR, CELLULAR DEVELOPMENTAL BIOLOGY - Regulation and function of NF- kB and related proteins; pleiotropic mediators of inducible gene expression.
PROFESSOR OF IMMUNOBIOLOGY - Human Translational Immunology. Pathogenesis and treatment of autoimmune disease, in particular Type 1 diabetes.
ASSOCIATE PROFESSOR OF IMMUNOBIOLOGY - Dendritic cells as mediators of antiviral mucosal immunity.
ASSISTANT PROFESSOR OF IMMUNOBIOLOGY - Mechanisms of memory T cell development.
PROFESSOR OF LABORATORY MEDICINE, GENETICS AND IMMUNOBIOLOGY - Human Immune Response to Chlamydia Trachamatis and Host-Pathogen Interaction. CD8 Co-receptor Ligand Iinteraction and Signal Transduction.
PROFESSOR OF IMMUNOBIOLOGY - Innate immune recognition, host-pathogen interactions, biology of inflammation, control of adaptive immunity, cell biology of signal transduction, control of gene expression, cancer biology.
PROFESSOR AND VICE-CHAIR OF IMMUNOBIOLOGY FOR HUMAN AND TRANSLATIONAL IMMUNOLOGY, PROFESSOR OF PATHOLOGY AND DERMATOLOGY - Immunobiology of vascular endothelial cells: cytokine actions and mechanisms; transplantation immunology.
ROFESSOR OF EPIDEMIOLOGY AND PUBLIC HEALTH (Microbial Diseases) AND IMMUNOBIOLOGY - Lymphotoxin (LT, TNF-ß, LT-a), LT-b and tumor necrosis factor-a (TNF-a): molecular regulation and roles in autoimmunity and lymphoid organ development.
PROFESSOR OF IMMUNOBIOLOGY - Biochemical mechanism and developmental regulation of V(D)J recombination and somatic hypermutation; lymphocyte development; mechanisms of DNA repair; function of the RAG1 and RAG2 proteins.
PROFESSOR OF LABORATORY MEDICINE AND IMMUNOBIOLOGY - Regulation and pathogenesis of autoantibody-producing B cells in normal and autoimmune mice; B-cell memory; mechanism of graft vs host/leukemia.
ASSISTANT PROFESSOR OF INTERNAL MEDICINE AND IMMUNOBIOLOGY - Mechanisms of antigen presentation, T cell effector function and regulation of Graft-vs.-Host Disease and Graft-vs.-Leukemia.
ASSOCIATE PROFESSOR OF IMMUNOBIOLOGY - Signal transduction through the MAPK cascades in immune regulation, mammalian target of rapamycin regulation of Akt/PKB and PKC, angiogenesis and cardiovascular development..
PROFESSOR OF DERMATOLOGY AND IMMUNOBIOLOGY - Immunobiology of gd T cells; immune system-skin interactions; immunopathogenesis of contact dermatitis, atopic dermatitis, and cutaneous T-cell lymphoma.