Yale School of Medicine

Department of Immunobiology

Department of Immunobiology

Department of Immunobiology
300 Cedar Street
The Anlyan Center
P.O. Box 208011
New Haven, CT 06520

Faculty

Dr. Jeffrey Bender

PROFESSOR OF MEDICINE AND IMMUNOBIOLOGY, ROBERT I. LEVY PROFESSOR OF PREVENTIVE CARDIOLOGY - Defining the cellular and molecular mechanisms which govern leukocyte-endothelial cell (EC) interactions and intercellular adhesion, in the context of cardiovascular disease.

Dr. Alfred Bothwell

PROFESSOR OF IMMUNOBIOLOGY AND INTERDEPARTMENTAL PROGRAM IN VASCULAR BIOLOGY AND TRANSPLANTATION - Immune responses to vascular interactions in human allo and xeno models; transplant immunobiology; function of murine Ly6 antigens; hematopoietic lineage differentiation.

Dr. Tian Chi

ASSISTANT PROFESSOR OF IMMUNOBIOLOGY - Chromatin remodeling and gene regulation in the immune system.

Dr. Joseph Craft

PROFESSOR OF MEDICINE AND IMMUNOBIOLOGY, CHIEF OF RHEUMATOLOGY, AND DIRECTOR OF INVESTIGATIVE MEDICINE - Activation, differentiation and effector function of CD4+ T cells in systemic autoimmunity.

Dr. Peter Cresswell

PROFESSOR OF IMMUNOBIOLOGY AND CELL BIOLOGY - Molecular mechanisms of antigen processing; assembly and intracellular transport of CD1 molecules, class I and class II MHC molecules; functions and mechanisms of action of interferon-induced proteins.

Dr. Richard Flavell

PROFESSOR AND CHAIRMAN OF IMMUNOBIOLOGY, PROFESSOR OF MOLECULAR, CELLULAR AND DEVELOPMENTAL BIOLOGY - Use of transgenic and gene-targeted mice to study T-cell tolerance and activation in immunity and autoimmunity. Apoptosis; regulation of T cell differentiation.

Dr. Sankar Ghosh

PROFESSOR OF IMMUNOBIOLOGY, MOLECULAR BIOPHYSICS AND BIOCHEMISTRY, AND MOLECULAR, CELLULAR DEVELOPMENTAL BIOLOGY - Regulation and function of NF- kB and related proteins; pleiotropic mediators of inducible gene expression.

Dr. Kevan Herold

PROFESSOR OF IMMUNOBIOLOGY - Human Translational Immunology. Pathogenesis and treatment of autoimmune disease, in particular Type 1 diabetes.

Dr. Akiko Iwasaki

ASSOCIATE PROFESSOR OF IMMUNOBIOLOGY - Dendritic cells as mediators of antiviral mucosal immunity.

Dr. Susan Kaech

ASSISTANT PROFESSOR OF IMMUNOBIOLOGY - Mechanisms of memory T cell development.

Dr. Paula Kavathas

PROFESSOR OF LABORATORY MEDICINE, GENETICS AND IMMUNOBIOLOGY - Human Immune Response to Chlamydia Trachamatis and Host-Pathogen Interaction. CD8 Co-receptor Ligand Iinteraction and Signal Transduction.

Dr. Ruslan Medzhitov

PROFESSOR OF IMMUNOBIOLOGY - Innate immune recognition, host-pathogen interactions, biology of inflammation, control of adaptive immunity, cell biology of signal transduction, control of gene expression, cancer biology.

Dr. Jordan S. Pober

PROFESSOR AND VICE-CHAIR OF IMMUNOBIOLOGY FOR HUMAN AND TRANSLATIONAL IMMUNOLOGY, PROFESSOR OF PATHOLOGY AND DERMATOLOGY - Immunobiology of vascular endothelial cells: cytokine actions and mechanisms; transplantation immunology.

Dr. Nancy Ruddle

ROFESSOR OF EPIDEMIOLOGY AND PUBLIC HEALTH (Microbial Diseases) AND IMMUNOBIOLOGY - Lymphotoxin (LT, TNF-ß, LT-a), LT-b and tumor necrosis factor-a (TNF-a): molecular regulation and roles in autoimmunity and lymphoid organ development.

Dr. David Schatz

PROFESSOR OF IMMUNOBIOLOGY - Biochemical mechanism and developmental regulation of V(D)J recombination and somatic hypermutation; lymphocyte development; mechanisms of DNA repair; function of the RAG1 and RAG2 proteins.

Dr. Mark Shlomchik

PROFESSOR OF LABORATORY MEDICINE AND IMMUNOBIOLOGY - Regulation and pathogenesis of autoantibody-producing B cells in normal and autoimmune mice; B-cell memory; mechanism of graft vs host/leukemia.

Dr. Warren Shlomchik

ASSISTANT PROFESSOR OF INTERNAL MEDICINE AND IMMUNOBIOLOGY - Mechanisms of antigen presentation, T cell effector function and regulation of Graft-vs.-Host Disease and Graft-vs.-Leukemia.

Dr. Bing Su

ASSOCIATE PROFESSOR OF IMMUNOBIOLOGY - Signal transduction through the MAPK cascades in immune regulation, mammalian target of rapamycin regulation of Akt/PKB and PKC, angiogenesis and cardiovascular development..

Dr. Robert Tigelaar

PROFESSOR OF DERMATOLOGY AND IMMUNOBIOLOGY - Immunobiology of gd T cells; immune system-skin interactions; immunopathogenesis of contact dermatitis, atopic dermatitis, and cutaneous T-cell lymphoma.