Publications

Selected Recent Publications

• Vratsanos G, Jung S, Park Y-M, Craft J. CD4+ T cells from lupus-prone mice are hyper-responsive to TCR engagement: A model to explain spontaneous T cell activation in lupus. J Exp Med 193:329-337, 2001.
• Shlomchik M, Craft J, Mamula M. From T to B and back again: Positive feedback in systemic autoimmune disease. Nature Rev Immunol 1:147-153, 2001.
• Yin Z, Chen C-H, Szabo S, Glimcher LH, Ray A, Craft J. T-bet dominance over GATA-3 leads to default production of IFN-gamma in gamma delta T cells. J Immunol 168:1566-1571, 2002.
• Yin Z, Bahtiyar G, Zhang N, Liu L, Zhu P, Robert M, McNiff J, Madaio MP, Craft J. IL-10 is a regulatory cytokine in murine lupus J Immunol 169:2148-2155, 2002.
• Fujii T, Okada M, Craft J. Regulation of T cell-dependent autoantibody production by a gamma delta T cell line derived from lupus-prone mice. Cell Immunol 217:23-35, 2002.
• Fujii T, Okada M, Mimori T, Craft J. The transmembrane form of TNF-alpha drives autoantibody production in MRL/Mp-Faslpr mice. Clin Exp Immunol 130:224-232, 2002.
• Bouzahzah F, Jung S, Craft J. CD4+ T cells from lupus-prone mice avoid antigen specific tolerance induction in vivo. J Immunol 170:741-748, 2003.
• Welte T, Zhang SS, Wang T, Zhang Z, Hesslein D, Yin Z, Kano A, Iwamoto Y, Li E, Craft J, Bothwell A, Fikrig E, Koni PA, Flavell RA, Fu X-Y. STAT3 deletion during hematopoiesis causes Crohn’s disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity. Proc Natl Acad Sci USA 100:1879-84, 2003.
• Gao Y, Yang W, Pan M, Scully E, Girardi M, Augenlicht LH, Craft J, Yin Z. gamma delta T cells provide an early source of IFN-gamma in tumor immunity. J Exp Med 198:433-442, 2003.
• Wang T, Scully E, Yin Z, Kim J-H, Wang S, Yan J, Mamula M, Anderson J, Craft J, Fikrig E. IFN-gamma producing gamma delta T cells help control murine West Nile virus infection. J Immunol 171:2524-2533, 2003.
• Kong PL, Zhu T-P, Madaio MP, Craft J. The role of the H-2 haplotype in Fas-intact lupus-prone MRL mice: association with autoantibodies but not renal disease. Arth Rheum 48:2992-2995, 2003.
• Ramsburg E, Tigelaar R, Craft J, Hayday A. Age-dependent requirement for gamma delta T cells in the primary but not secondary protective immune response against an intestinal parasite. J Exp Med 198:1403-1414, 2003.
• Kang I, Quan T, Nolasco H, Park S-H, Hong M S, Crouch J, Pamer EG, Howe JG, Craft J. Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. J Immunol 172:1287-1294, 2004.
• Kong PL, Morel L, Croker B, Craft J. The centromeric region of chromosome 7 from MRL mice (Lmb3) is an epistatic modifier of Fas for autoimmune disease expression. J Immunol 172:2785-2794, 2004.
• Kang I, Hong M-S, Nolasco H, Park S-H Dan J, Craft J. Age-associated change in the homeostasis of memory CD4+ T cells impairs long-term CD4+ T cell responses to influenza vaccine. J Immunol 172:7399-7407, 2004.
• Choi JY, Craft J. Activation of naïve CD4+ T cells in vivo by a self-peptide mimic: Mechanism of tolerance maintenance and preservation of immunity. J Immunol 173: 673-681, 2004.
• Zielinski C, Jacob S, Bouzahzah F, Ehrlich B, Craft, J. Naive CD4+ T cells from lupus-prone MRL mice display TCR-mediated hyper-proliferation due to intrinsic threshold defects in activation. J Immunol 174:5100-9, 2005.
• Mizue Y, Ghani S, Leng L, McDonald C, Kong P, Baugh J, Lane S, Craft J, Nishihira J, Donnelly S, Zhu Z, Bucala R. Role for macrophage migration inhibitory factor in asthma. Proc Natl Acad Sci USA 102:14410-5, 2005.
• Shrestha B, Wang T, Samuel M, Whitby K, Craft J, Fikrig E, Diamond M. INF-gamma plays a crucial early antiviral role in protection against West Nile virus infection. J Virol 80:1340-1351, 2006.
• Wang T, Gao Y, Scully E, Davis CT, Anderson JF, Barrett A, Ledizet M, Koski R, Yin Z, Craft J, Fikrig E. gamma delta T cells facilitate adaptive immunity against West Nile virus infection. J Immunol 177:1825-1832, 2006.
• Choi J, Gao W, Odegard J, Shiah HS, Kashgarian M, McNiff J, Baker D, Cheng Y, Craft J. A novel Tylophorine analog that inhibits NF-kB abrogates skin disease in lupus-prone MRL-Faslpr mice. Arth Rheum 54:3277 – 3283, 2006.
• Chen L, Kim ST, He W, Tao J, Gao Y, Chi H, Intlekofer AM, Harvey B, Reiner SL, Yin Z, Flavell R, Craft J.  Both epigenetic and transcriptional programs lead to default IFN-gamma production by gd T cells.  J Immunol. 178:2730-2736, 2007.