Publications

Selected Publications

• Hesslein, D.G.T., Pflugh, D.L., Chowdhury, D., Bothwell, A.L.M., Sen, R. and Schatz, D.G. Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments. (2003). Genes Dev. 17:37-42.
• Zhang, Z., Jimi, E. and Bothwell. (2003). A.L.M. Receptor Activator of NF-kB Ligand stimulates recruitment of SHP-1 to the complex containing TNFR-Associated Factor 6 that regulates osteoclastogenesis. J. Immunol. 171:3620-3626.
• Schechner, J.S., Crane, S., Wang, F., Szeglia, A., Tellides, G., Lorber, M., Bothwell, A.L.M. and Pober, J.S. (2003). Engraftment of a vascularized human skin equivalent. FASEB J. 17:2250-2256.
• Johnson, K., Pflugh, D.L., Yu, D., Hesslein, D.G.T., Lin, K.-I., Bothwell, A.L.M., Thomas-Tikhonenko, A., Schatz, D.G. and Calame, K. (2004). B-cell specific loss of histone 3K9 methylation in the VH locus depends on Pax5. Nat. Immunol. 5:853-861.
• Horowitz, M.C., Xi, Y., Pflugh, D.L., Hesslein, D.G.T., Schatz, D.G., Lorenzo, J.A. and Bothwell, A.L.M. (2004). Early onset osteopenia with increased osteoclast progenitors in Pax5 deficient mice. J. Immunol. 173:6583-6591.
• Fernandez-Cabezudo, M.J., Vijayasarathy, C., Bothwell, A.L.M. and al-Ramadi, B.K. (2004). Evidence for a dual pathway of activation in CD43-stimulated Th2 cells: Differential requirements for the Lck tyrosine kinase. Int. Immunol. 16:1215-1223.
• Torpey, N., Maher, S.E., Bothwell, A.L.M. and Pober, J.S. (2004). Interferon a but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells. J. Biol. Chem. 279:26789-26796.
• Zheng, L., Gibson, T.F., Schechner, J.S., Pober, J.S. and Bothwell, A.L.M. (2004). Bcl-2 transduction protects human endothelial cell synthetic microvessel grafts from allogeneic T cells in vivo. J. Immunol. 173:3020-3026.
• Zhang, Z., Welte, T., Troiano, N., Maher, S.E., Fu, X.-Y. and Bothwell, A.L.M. (2005). Severe osteoporosis with increased osteoclastogenesis in hematopoietic cell-specific STAT3 deficient mice. Biochem. Biophys. Res. Commun. 328:800-807.
• Pflugh, D.L., Bynoe, M.S., Maher, S.E., Wickens, C. and Bothwell, A.L.M. Ly-6A expression is required for the generation of regulatory T cell activity in the periphery. Submitted.