Current Research Activities in Kidd Lab

Department of Genetics, Yale University School of Medicine

Projects

Alcohol metabolism and alcoholism

Examples of particular genes/gene regions under study	Selected publications exploring theme
ADH@ alcohol dehydrogenase gene cluster on chr 4	Han et al., (2007)
ALDH2 aldehyde dehydrogenase 2 on chr 12	Oota et al., (2004)
TAS2R38 taste receptor, type 2, member 38 on chr 7	Duffy et al., (2004)

Human population origins and evolution

Examples of particular datasets and analyses	Selected publications exploring theme
The pattern of human diversification	Tishkoff & Kidd., (2004)
ADH Molecular Evolution	Oota et al., (2007)
SNPs and haplotypes on populations	Kidd et al., (2004)
STRPs on CEPH Diversity Panel	Rosenberg et al., (2002)
*ADH1B47His geographic distribution**	Li et al., (2007) Li et al., (2008)
Ancestry informative SNPs in East Asia	Kim et al., (2005)

Signals of natural selection

Examples of particular datasets and analyses	Selected publications exploring theme
Selection for ADH1B	Han et al., (2007)

Linkage Disequilibrium

Examples of particular genes/gene regions under study	Selected publications exploring theme
Haplotype frequencies at DRD2, HOXB, PAH	Kidd et al., (2000) Kidd et al., (2004)
Quantifying LD along a segment of DNA	Sawyer et al., (2005)
LD and transferability of tagging SNPs	Gu et al., (2007)

Neuropsychiatric disorders—candidate genes

Examples of particular genes/gene regions under study	Selected publications exploring theme
17q25 near TBCD (Tourette syndrome)	Paschou et al. (2004) Speed et al. (2008)
COMT chr 22 (schizophrenia)	Palmatier et al. (2004) Mukherjee et al. (2008)
ADH chr 4 (alcoholism)	Han et al., (2007) Li et al., (2007)