Publications
Lockshon, D., Zweifel, S.G., Freeman-Cook,
L.L., Lorimer, H.E., Brewer, B.J., and Fangman, W.L.
(1995) A role for recombination junctions in the segregation
of mitochondrial DNA in yeast. Cell 81:947-955.
Sherman, J.M., Stone, E.M.,
Freeman-Cook, L.L., Brachmann, C.B., Boeke,
J.D., and Pillus, L. (1999) The conserved core of a human SIR2
homologue functions in yeast silencing. Mol. Biol. Cell
10:3045-3059.
Freeman-Cook, L.L.,
Sherman, J., Brachmann, C., Boeke, J., Nimmo, E., Alshire, R.,
and Pillus, L. (1999) The S. pombe hst4+ gene is a SIR2 homologue
with silencing and centromeric functions. Mol. Biol. Cell
10:3171-3186.
Freeman-Cook, L.L.,
Dixon, A.M., Frank, J.B., Xia, Y., Ely, L., Gerstein, M., Engelman,
D.M., and DiMaio, D. (2004) Selection and characterization of
small random transmembrane proteins that bind and activate the
platelet-derived growth factor ß receptor. J. Mol.
Biol. 338:907-920.
Freeman-Cook, L.L.,
Edwards, A.P.B., Dixon, A.M., Yates, K.E., Ely, L., Engelman,
D.M., and DiMaio, D. (2005) Specific locations of hydrophilic
amino acids in constructed transmembrane ligands of the platelet-derived
growth factor ß receptor. J. Mol. Biol. 345:907-921.
Freeman-Cook
L.L., Gomez EB, Spedale EJ, Marlett J, Forsburg SL,
Pillus L, and Laurenson P. (2005) Conserved locus-specific silencing functions
of Schizosaccharomyces pombe sir2+. Genetics 169:1243-1260.
Freeman-Cook, L.L.
and DiMaio, D. (2005) Modulation of cell phenotype by small
transmembrane proteins modeled on the bovine papillomavirus
E5 protein. Oncogene 24: 7756-7762.
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