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Satcher’s message of prevention
In visit to Yale, surgeon general cites public health challenges

Human behavior, according to Surgeon General David Satcher, M.D., Ph.D., is the most important factor in the public health challenges facing the nation. In conversations with students and in a speech to library associates this spring, Satcher said that smoking, poor nutrition and physical inactivity are responsible for hundreds of thousands of deaths each year. Half of all deaths derive from nine behaviors, he said in his keynote address, “Toward a Balanced Community Health System: Opportunities and Challenges,” delivered March 24 at the 51st annual meeting of the Associates of the Cushing/Whitney Medical Library. And medicine expends a disproportionate amount of its resources on treatment of late-stage disease rather than health promotion and disease prevention, he said.

Treatment, he pointed out, fails to reach all social groups and classes equally. “We have the most sophisticated health care system in the world,” he said. “Yet there are tremendous disparities on the basis of race and ethnicity. An African-American baby born in this country is two times as likely to die in the first year of life as a majority baby.”

Over lunch he took questions from medical, public health and nursing students who had traveled abroad on research fellowships or spent time working in inner-city hospitals and homeless shelters. What, asked Kebba Jobarteh, did Satcher think about controversial AZT trials designed to reduce vertical transmission of HIV in the Third World? “We were criticized by people I respect a lot,” answered Satcher, who, as director of the Centers for Disease Control and Prevention, endorsed the trials that used placebos in a control group. The study found that use of AZT could reduce the spread of AIDS from pregnant mother to child, even if the first dose is administered during labor. “That controversial study is saving thousands of lives every day,” Satcher said.

Did he foresee, asked Rachel Lovins, any changes in the nation’s health insurance system? “There is no way we are going to control costs as long as we focus on treatment of patients after they are sick,” he said. “There is not enough incentive for health promotion and disease prevention.” Satcher expressed hope that frustration with the current system would pave the way for his balanced approach.

 

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Yale delegation brings high-tech care to remote corner of Peru

Two Yale plastic surgeons traveled to the Peruvian Amazon in March, where they performed about 80 operations for people in need of corrective surgery. John A. Persing, M.D., chief of the section of plastic surgery, and Joseph Shin, M.D., HS ’97, assistant professor of plastic surgery, went as part of Interplast, an agency that sends doctors around the world to do charitable work. Their trip to Iquitos, Peru, a port on the Amazon accessible only by air or water, was sponsored by the Ronald McDonald House. Interplast was founded in 1965 by Yale alumnus Donald R. Laub, M.D. ’60, HS ’63, now at Stanford University.

The surgeons each spent a week in Iquitos, part of a team of 16 people that included nurses, an obstetrician-gynecologist and a pediatrician. Of the 80 operations Persing and Shin performed, most were for cleft lip and palates. They also operated on burn patients and removed a tumor on the nose of a 90-year-old woman. “We try to serve the needs of the local population,” said Shin, “although the emphasis is on cleft palates and congenital malformations.” This was Shin’s second trip on behalf of Interplast and Persing’s fifth since 1993.

As part of their program they are following up on their patients’ recoveries via information sent by local doctors on the Internet. Two Web sites, http:// www.wiredMD.com and http:// yalesurgery.med.yale.edu, carry the information. Part of the doctors’ mission is to provide training to local physicians, both during their visit and afterwards over the Internet. “The initial goal,” says Persing, “is to provide service for people who would not be able to afford care. The secondary goal is to magnify our effect by teaching local surgeons how to do the work.”

 

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Telemedicine proves its mettle
on Mt. Everest

In May 1998, a team of Yale physicians trekked to the slopes of Mt. Everest to provide medical support for climbers and to conduct research on the body’s response to high altitude and thin air. They brought along equipment to record how fast climbers’ hearts pumped and how well their lungs worked in those extreme conditions on the world’s highest mountain.

At the core of the expedition was a system to transmit that information from climbers high on the mountain to the expedition’s makeshift medical center at the Everest Base Camp at 17,500 feet, and then around the globe to New Haven.

This spring, a second Yale team returned to Everest to continue the work of that first expedition and quickly found an opportunity to prove the value of telemedicine in an emergency. On May 14, as physicians on the mountain were beginning their daily videoconference with colleagues in New Haven, a climber stumbled into the medical tent, wheezing and coughing. The climber had reached Everest Camp Four, at 26,000 feet above sea level, before turning back with breathing difficulties that worsened even as he descended into the fuller air of lower altitudes.

Tests showed that his blood oxygen was low and that little air was moving through the lower part of his lungs. Suspecting either pneumonia or the potentially fatal condition known as high-altitude pulmonary edema, his physicians used the expedition’s electronic network to consult in real time with their colleagues in New Haven. They sent ultrasound images of the climber’s lungs, along with digitized blood smears and sputum samples, to Yale for further analysis, and the diagnosis of pneumonia was confirmed. The clinical data traveled the 15,000 miles in an instant — by satellite from Base Camp to a relay station in Malaysia, then to the United States and onto Yale via the Internet.

After two days of antibiotics, oxygen and an IV to treat dehydration, the climber left the medical tent. “He was able to walk down to lower altitudes, where he continued to improve,” said Richard Satava, M.D., of the Commercial Space Center for Medical Informatics and Technology at Yale, which was responsible for the expedition. Yale’s partners in the expedition were the Explorers Club and Millennium Healthcare Solutions Inc. Olympus America was a major sponsor of the expedition. Ronald C. Merrell, M.D., former chair of surgery, was the driving force behind the school’s telemedicine efforts.

The consultation that spanned an ocean and two continents proved the viability of the communications technology, which is being developed for the National Aeronautics and Space Administration. “We are hoping that the success of this year will be enough to encourage NASA to put some of these things on the space station and the mission to Mars,” Satava said.

The expedition’s research also expanded knowledge of the effects of hypoxia on the cardiovascular system. Previous studies concentrated on the pulmonary system, Satava said. “We now have specific measurements about how the heart and blood vessels adapt to low oxygen,” he said.

Last year’s lesson was that a telemedicine station in remote terrain could transmit to a medical center thousands of miles away, said Peter Angood, M.D., program director for the Yale Surgical Critical Care program, and a member of the support team at Yale. But during that first expedition the technology was not always successful. Personal status monitors, designed to measure climbers’ temperature, heart rate, breathing and location, often failed to transmit the information to Base Camp. This year climbers successfully repositioned repeaters, the line-of-sight devices that transmit data from the climbers’ monitors to Base Camp. Upgraded personal status monitors proved better able to transmit data to Base Camp than last year. On May 12 three climbers wore them on a trek to Camp One at 21,000 feet, while the Yale support team monitored them in real time.

Physicians on the team again opened a clinic at Base Camp, where they treated routine high-altitude ailments — headaches, insomnia and gastrointestinal disorders — as well as medical emergencies such as frostbite and physical injuries. The expedition team included a resident in ophthalmology who conducted research into the effects of high altitude on sight. “Surprisingly,” said Angood, “there is very little good research on what happens to the eyes in high altitude. With the pressure changes the contours of the eyeball itself change.” On May 18, M. Bruce Shields, M.D., chair of ophthalmology and visual science, consulted with the resident, Jennifer Grin, M.D., on a case of retinal hemorrhage. A video fundoscopic exam had revealed the hemorrhaging, and Shields also identified venous congestion in the retina.

In addition to caring for sick and injured climbers, the team’s physicians conducted regular tests on a core group of seven climbers. Every other day the climbers went through a 90-minute exam that measured, among other things, cardiac output, oxygen saturation, mental and visual acuity and cognitive functions. The tests started before the team members left the United States so their physiological measurements at sea level could be compared with readings in the mountains. The team’s medical devices included a small camera that fits under the tongue and reveals how small blood vessels change shape and caliber.

The next step in the project is, Satava said, “up in the air.” An expedition to Everest, or another remote site, depends on the results of this year’s research and the availability of corporate support. “There are other environments that similar concepts and ideas could be tested out on,” Angood said. “It doesn’t have to be Everest.”


Also in Scope:


Satcher's message of prevention  
|  A remote corner of Peru gets high-tech care  |  Telemedicine proves its mettle  |  The ethics and science of HIV  |  EPH grand rounds  |  Non-traditional medicine  |  Breast cancer study  |  Musculoskeletal research  |  What's in a yam?  |  Ways to ward off delirium  |  Estrogen treatment increases brain activity  |  Magnetic stimulation offers relief to schizophrenia patients     

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Originally published in Yale Medicine, Summer 1999.
Copyright © 1999 Yale University School of Medicine. All rights reserved.