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From Kosovo to college, with a detour near Cedar Street

Two years ago, when a group of Yale medical students volunteered at a camp for Kosovo refugees, second-years Aaron Covey and Seth Goldbarg found themselves working triage in the camp hospital. As new arrivals stepped off the buses at Senekos, a makeshift city of white tents in neighboring Macedonia, the students assessed the refugees and directed those who were ill to medical care.

When they met 18-year-old Irfan Baftiu, who had been in the camp for several days and had come to the triage center simply to make himself useful, there was a little confusion. “I kept trying to help,” Irfan recalled, “and Aaron kept trying to give me water.”

But soon Irfan and his younger brother, Bafti, then 15, were close to indispensable. “They helped us with every project we did in the camp,” said Margaret Bourdeaux, another of the six Yale students who were assisting the camp’s medical staff (“Kosovo Journal,” Summer 1999). Irfan and Bafti, who had learned English from watching American television and movies, translated for patients and doctors, worked on a tent-to-tent health survey and a nutritional assessment of the children in the camp, and helped organize a soccer tournament and a theatrical production. “From the minute we met them,” said Covey, “we realized they were incredibly bright, with so much potential and such a desire to help.”

A year later, the two boys were a world away from battered Kosovo, enrolled at a New England boarding school and living less than an hour’s drive from their medical-student mentors in New Haven. The combined efforts of many—the boys’ American sponsor (an emergency physician from Ohio whom they met in the camp), the medical school dean’s office, the Loomis Chaffee School in nearby Windsor, Conn., and the medical students—resulted in student visas for Irfan and Bafti and a year of study to help them prepare for college. Loomis Chaffee provided full scholarships with room and board for the boys to attend a summer program as well as their final year of high school.

This summer the brothers moved to Cleveland and the home of their sponsor, Pamela Grim, M.D. In the fall, they will study at Oakland Community College in Michigan, work on their written English skills and think about the future. Bafti, who had a good year in math, is thinking about business.

His brother hopes to become a physician. “I saw a lot of things in Kosovo and in the camp that are pushing me in that direction,” Irfan said in April. “I saw victims of land mines. I saw the operating room and what they could do for them. And I know that I really want to help people.”

 

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Emergency Department opens its doors for Learning Channel documentary

When a 37-year-old New Haven man leaped from the third story of a burning building and was rushed to Yale-New Haven Hospital, filmmakers from The Learning Channel met him at the E.R. door alongside the trauma team.

The story of the injured man was among dozens of trauma and emergency room cases followed by “shooters” from TLC’s reality TV show, Trauma: Life in the E.R. To gather raw footage for the show, a producer and three video journalists endured schedules to rival a resident’s, recording life in the Emergency Department 24 hours a day, seven days a week, for a month this spring.

From 250 hours of videotape recorded on hand-held cameras, producer Penny Fearon will distill two 47-minute documentaries, one to be aired this fall and the other sometime in 2002. The award-winning show attracts an average audience of 1.5 million on Tuesday nights at 8 p.m., according to Nielsen Media Research.

Yale-New Haven Hospital will be the first in New England to be featured on the five-year-old show. Series producer Brian Seligson said Yale-New Haven appealed to him because of the contrasts afforded—“on the one hand, Yale University and everything it represents, and on the other hand, the fact that it’s an inner-city hospital
dealing with an inner-city population.”

How the film will be edited, and consequently how the hospital will be portrayed, is in the hands of The Learning Channel, said Reuven Rabinovici, M.D., professor of surgery and chief of the section of trauma and surgical critical care. The confluence of The Learning Channel’s real-life depiction of the trauma world and his team’s ability to provide cutting-edge trauma care leaves him confident the team will come across positively.

“To care for a trauma patient, you need to have an endogenous sense of mission and responsibility, because it’s very intense. The people involved are doing their best to provide optimal care, whether they are on camera or off.”

Producer Fearon will choose a few people to follow—physicians, nurses, patients—to create two shows with recognizable characters and coherent plot lines. She said the “shooting ratio” of tape to finished product is luxurious, at more than 150 hours to 1 compared to the 50-to-1 ratio typical for reality TV documentaries. One show will document the story of the man who jumped from the building, following him as he is treated for smoke inhalation and through surgery for a broken femur and heel until, after three weeks at Yale-New Haven, he heads out the door.

 

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Clinical development fund makes first round of awards

Two years ago, when Yale University and the Yale New Haven Health System signed their first formal affiliation agreement, one of its provisions was a fund to expand the joint clinical programs of the School of Medicine and Yale-New Haven Hospital.

In May, the two institutions announced the first awards from this new Clinical Program Development Fund, directing $17.6 million this year to 11 programs in brain disorders, cancer, cardiovascular disease, developmental disorders and organ transplantation. These areas have been designated clinical priorities by the school and hospital.

“We want to position the medical center at the top of the field in as many target areas as possible,” said Richard L. Edelson, M.D. ’70, co-chair of the fund and deputy dean for clinical affairs. “[This investment] is intended to allow these programs to push the envelope and, in some cases, to define the frontier.”

The funded proposals and investigators include:

Brain Disorders

• Clinical Neuroscience Center for Epilepsy and Neurovascular Diseases, Dennis Spencer, M.D.

• Yale-New Haven Medical Center Brain Tumor Center, Joseph Piepmeier, M.D., HS ’82.

Cancer

• Transimmunization: A New Method for Treatment of Graft vs. Host Disease, Prevention of Graft Rejection and Immunization against Tumor Antigens, Michael Girardi, M.D. ’92.

• Expansion of the Yale Cancer Center Clinical Trials Office, Leonard Farber, M.D.

• New Infrastructure and Organization for the NCI- Approved Yale Comprehensive Cancer Center, Vincent DeVita Jr., M.D., HS ’66.

• Innovations of Head and Neck Management, Clarence Sasaki, M.D. ’66, HS ’73.

Cardiovascular Disease

• Yale-New Haven Medical Center Endovascular Center,
Bauer Sumpio, M.D., HS ’86.

• Integrated Program for the Treatment of End-Stage Heart Disease, Barry Zaret, M.D.

• Endovascular Brachytherapy, Kenneth Roberts, M.D.

Developmental Disorders

• Yale-New Haven Medical Center Oncofertility Center, Steven Palter, M.D.

Organ Replacement

• Transplantation, Marc Lorber, M.D.

The fund received 23 proposals in the first round with requests totaling $69.1 million and awarded $17.6 of the $18 million available. Two committees, co-chaired by Edelson and Peter Herbert, M.D. ’67, HS ’69, chief of staff at Yale-New Haven Hospital, are now reviewing a second round of applications for $11.5 million in support.

 

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The Giff tackles “retirement”

A former dean spends his days teaching science to grade-schoolers in New Haven’s Hill neighborhood

On a Wednesday morning in early January, Robert H. Gifford, M.D., HS ’67, took nine of his eighth-grade students out onto New Haven’s Columbus Avenue for an experiment. Braving a wind chill of 4 degrees, they measured the length of the block in front of Sacred Heart/St. Peter School and prepared to calculate the speed of passing cars. The parochial school is the last of several serving the Hill neighborhood, which borders the medical school campus to the south and west, and Gifford, the former deputy dean of education at Yale, is the school’s new science teacher. In fact, he is its only full-time science teacher.

The hours are long, the work is challenging and the pay is modest. (Gifford, who volunteered his services during his first semester at the school, now receives a small salary.) But it fulfills the goal he set several years before his retirement in 1999 [“Goodbye, Dr. Gifford,” Fall 1999|Winter 2000] of teaching science to children in New Haven’s inner city. The lack of a required state teaching certificate thwarted Gifford’s original plan to teach in city public schools. But his name came to the attention of Geraldine Giaimo, M.S., the principal of Sacred Heart/St. Peter, who was looking for a way to offer students more science than the classroom teachers could incorporate into their lessons.

Although Sacred Heart/St. Peter is a parochial school, only about 30 percent of its students are Roman Catholic. Of the 224 students enrolled, 96 percent are African-American or Latino and 62 percent meet federal guidelines for free or reduced-rate breakfasts and lunches at the school. “We were actually in tears when [Gifford] said he would come here,” said Giaimo, herself an alumna of Sacred Heart, which merged with St. Peter School in 1994. “He’s not just the science teacher. He’s the science department.”

Both Gifford and his students, who are in grades four through eight, have made some adjustments. For Gifford, Giaimo said, “It’s very challenging dealing with young people.” And for the students? “The work is hard,” she said. “He expects a lot from them.”

Gifford’s main teaching tool is a multimedia computer that allows him to project Web pages onto a screen. His curriculum, which he wrote last summer, is based on national standards for science education and has no textbook. “This way I can go in any direction I really want to,” he said. The direction usually involves an experiment, because he wants the students to learn by doing and thinking. The program’s objective, he wrote in his curriculum, is for students to develop an enthusiasm for the natural world and an appreciation of scientific thought. With donated funds, he bought science kits that allow the students to carry out the experiments that underpin his teaching.

Which explains why Gifford and nine students were freezing outside the school, armed with notepads, stopwatches and a tape measure. Their hypothesis was that few drivers passing the school adhered to the posted 25-mile-per-hour speed limit. The students further hypothesized that men were more likely to disregard the limit than women.

Before leaving the warmth of the classroom, Gifford reviewed the required math, leading them through the calculations necessary to translate feet per second into miles per hour. “Tomorrow,” said Gifford, “we’re going to construct a graph that will allow us to know, so we don’t have to calculate it all the time.” After measuring the speed of three cars, Gifford and the students gave in to the cold and went inside, vowing to return another day to collect more data. “No one’s going the speed limit, that’s for sure,” Gifford said, noting that a much larger sample was needed for the study. “We need a lot of cars. We need well over 100 cars.”

At a school science fair in February, the students presented their results. They surveyed 206 cars and found that 81 percent exceeded the speed limit, that 85 percent of female drivers and 79 percent of male drivers exceeded the limit, that all westbound cars and 91 percent of eastbound drivers were speeding and that the average speed was 35 miles per hour.

At Sacred Heart/St. Peter, his last class is over by 12:35 p.m., but Gifford often spends afternoons at the school. He arranges for after-school tutoring for students who need it. He recently offered his fellow teachers in-service training on classroom applications of the Internet. And he’s working with K–3 teachers to develop a science curriculum they can use in the classroom. “I felt I could bring something to the school they didn’t have,” Gifford said, explaining his decision to volunteer as a teacher. “It was an opportunity.” Giaimo couldn’t agree more. “He is laying a foundation,” she said, “in a way that I don’t think anyone else could.”

 

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Smart cards for health care’s future?

Before the end of the decade, patients may be arriving at the doctor’s office with their personal genetic information encoded on a smart card to help their physicians tailor their treatment. But who else will have access to that personal information? Those were among the visions and concerns for the future of health care presented at the fourth annual Pharmacogenetics and Medicine Lectures at the School of Medicine in early April. The conference brought together experts in genomics, medicine and policy to discuss the changes in medicine resulting from emerging information about the relationship between an individual’s genetic makeup and both the health benefits and detrimental side effects of medications.

Pharmacogenetics is the rapidly developing field that applies new tools based on genetic differences to drug development and, eventually, to choosing the best treatments for patients. The morning-long event in Harkness Auditorium drew nearly 200 attendees from the medical school and from biotechnology, pharmaceutical and venture capital firms around the Northeast.

Gualberto Ruaño, Ph.D. ’92, M.D. ’97, is chief executive officer of the conference sponsor, Genaissance Pharmaceuticals, a New Haven firm that is discovering the associations between genetic variations and clinical outcomes that will make those smart cards possible. He predicted that within the next five to six years smart cards will begin to be a part of health care practices and will quickly become standard medical technology for prescribing medications. Genomics, he said, can be predictive. “At the end of the day, our purpose is to create a genetic PDR,” the equivalent of the Physician’s Desk Reference used by doctors for guidance in prescribing medications.

Gail Wilensky, Ph.D., is a senior fellow at the Center for Health Affairs/Project HOPE, an international health foundation, and chair of the Medicare Payment Advisory Commission, which advises Congress on Medicare issues. She pointed out that there is a great deal of skepticism about the current value of health care relative to costs, but was optimistic that pharmacogenetics will receive support. “The promise of better targeting of pharmaceuticals,” she said, is “better value for our money.”

Medical ethicist and Professor of Medicine Robert J. Levine, M.D., HS ’63, noted the importance of maintaining patient privacy and making improvements in health care as a result of pharmacogenetic advances becoming widely accessible. Without dealing with public fears, achieving personalized medicine may not be so easy, warned Alan McGowen, president of the Gene Media Forum, a public information organization that focuses on biomedical science. “We can avoid the pitfalls,” he said, “if we take a very strong stance in educating the public about the benefits and are honest about the risks in this research.”

 

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Talking about health

Students from Yale’s health professions joined with city and state health officials for Spring Into Health Fair on Communiversity Day in April. At tables set out on the University’s Old Campus, students in medicine, public health, nursing and the Physician Associate Program offered information about a variety of health topics including smoking prevention and cessation, asthma and dental health. They also provided information about nutrition and health insurance as well as blood pressure screenings. Among the hands-on events was a chance to learn CPR with a mannequin. Organizers hope this will become an annual event and timed it to coincide with Communiversity Day on April 7. “Given that there are going to be hundreds of people here, it’s an incredible public health opportunity,” said Sara Schulman, M.P.H. ’01, co-chair of the event with second-year medical student Grace Suh.


Also in Chronicle:

From Kosovo to college  |  ED opens doors for Learning Channel  |  Clinical fund makes first awards  The Giff tackles "retirement"  |  Smart cards for health care's future?  |  Talking about health

Rounds  |  Findings  |  Et cetera   

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Originally published in Yale Medicine, Summer 2001.
Copyright © 2001 Yale University School of Medicine. All rights reserved.