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BOOKSHELF
Coping with life’s everyday
fears
BOOK NOTES
Book notes
IN CIRCULATION
Consortium seeks to boost minority
presence in health information professions
ON CAMPUS
Paul Carlton
Judah Folkman
Jack El-Hai
Dikembe Mutombo

Steven Marans draws on clinical research and his own experiences to explore
the fundamental fears all people share.
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Coping with life’s
everyday fears
Drawing lessons from trauma, author offers parents advice on a child’s
anxieties, large and small.
By Cathy Shufro

It was 3 a.m. on a summer night in 2004 when the sound of a pager awoke
psychoanalyst Steven R. Marans, M.S.W., Ph.D. The New Haven police were
summoning him to a home where three children had witnessed a murder. Along
with colleagues in the city’s Child Development-Community Policing
Program (which Marans founded with the late Donald J. Cohen, M.D. ’66,
in 1991), Marans invited the children to draw pictures and to talk about
any aspects of the event they wished to discuss.

As a nationally known expert on children facing severe trauma, Marans
spends much of his time helping children and those who care for them to
cope with major upheavals—domestic violence, school shootings, the
9/11 attacks and such natural disasters as Hurricane Katrina. Since 2000
he has also directed the National Center for Children Exposed to Violence,
a federal program based on Yale’s partnership with the New Haven
police.

Now Marans, professor of child psychiatry and psychiatry at the Yale Child
Study Center and in the department of psychiatry, has applied his insights
to writing a guide for parents that explores the day-to-day challenges
of growing up. In his first book for a general audience, Listening
to Fear: Helping Kids Cope, From Nightmares to the Nightly News, Marans
suggests that children’s reactions to stress have a common source.
Whether the stressor is as extreme as witnessing a murder or as ordinary
as coping with teasing, the common source is fear.

Marans, who has been trained in both child and adult psychoanalysis, shows
in his book how fear enters into everyday events with a description of
a supermarket tantrum by his toddler son (now a college student). For
the child, fear played a role—perhaps he feared his lack of competence
when his father had to lift him to reach a container of sour cream. Most
likely the child also scared himself with his outburst. But the incident
stirred Marans’ own fears: loss of control, loss of his self-image
as someone skilled in understanding children—and loss of face as
he imagined onlookers judging him a bad parent. Those fears Marans could
explain rationally.

Marans says that children’s fears also evoke their parents’
suppressed fears, fears that stem from the normal course of development
and from their own childhood experiences. “We desperately want to
wave the proverbial magic wand and wave our children’s feelings
away, not only because we don’t like to see our children unhappy
but also because it stirs up our own feelings—feelings that we’re
reminded of by our kids’ experiences,” said Marans.

Drawing on clinical research and his own experience, Marans said all people
share five fundamental fears: loss of life (of loved ones and of oneself);
loss of the love of others and for ourselves; bodily harm; losing control
of our feelings, impulses or thoughts; and losing the assumed predictability
of daily life. By distinguishing our own fears from our child’s,
Marans said, we become better parents. We need to listen, not only to
words but also to behavior, which may be the child’s only means
of expressing distress.

“My interest in extreme situations is an extension of the concern
that I always have: how we use our understanding of human behavior and
human development as a way of illuminating people’s experience,”
said Marans during an interview at the Child Study Center. “What
I hope the book does is remind us that the worst of our fears, fears that
can reach overwhelming or dramatic proportions, are elaborations of the
basic fears and anxieties that are part of who we are as human beings.
Discovering that there is, in fact, sense to what we feel and how we act
can be tremendously reassuring.”

Bookshelf is a column in Yale Medicine focusing on matters related
to books and authors at the School of Medicine. Send ideas to Cathy Shufro
at cathy.shufro@yale.edu.
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Book notes
Smoking 101: An Overview for Teens
by Margaret O. Hyde and John F. Setaro, M.D., HS ’86, FW ’92,
associate professor of medicine (cardiology) (Twenty-First Century Books)
This book provides information that will help teenagers considering whether
to try cigarettes. For teens who already smoke, the authors describe programs
and techniques for quitting and list websites of organizations that can
help.

On Call: A Doctor’s Days and Nights in Residency
by Emily R. Transue, M.D. (St. Martin’s Press) While a resident
at the University of Washington, Transue, Yale College Class of 1992,
wrote about her patients as a way to guard against burnout and share her
experiences with friends and family. This collection of stories conveys
the atmosphere of overwork, exhaustion and insecurity in which a resident
works, as well as Transue’s compassion for her patients.

Mortal Secrets: Truth and Lies in the Age of AIDS
by Robert Klitzman, M.D. ’85, and Ronald Bayer, Ph.D. (The Johns
Hopkins University Press) The authors provide a portrait of moral,
social and psychological decision making by drawing on interviews and
testimonies from more than 70 gay men and women, intravenous drug users,
sex workers, bisexual men and heterosexual men and women. For those who
are HIV-positive, decisions about disclosure of their diagnosis make them
confront intimate questions about truth, lies, sex and trust.

Shields’ Textbook of Glaucoma
edited by R. Rand Allingham, M.D., Karim F. Damji, M.D., Sharon F.
Freedman, M.D., Sayoko E. Moroi, M.D., Ph.D., George Shafranov, M.D.,
associate professor of ophthalmology and visual science, and M. Bruce
Shields, M.D., the Marvin L. Sears Professor of Ophthalmology and Visual
Science (Lippincott Williams & Wilkins) Readers will find updated
information on the cellular and molecular biology of the eye, molecular
genetics of glaucoma and congenital and developmental glaucomas. The book
also describes management of glaucoma and approaches to treatment. Each
chapter includes summaries of key points.

Psychological Aspects of Reconstructive and Cosmetic Plastic Surgery:
Clinical, Empirical and Ethical Perspectives
edited by David B. Sarwer, Ph.D., Thomas Pruzinsky, Ph.D., Thomas F.
Cash, Ph.D., Robert M. Goldwyn, M.D., John A. Persing, M.D., professor
of surgery (plastic) and neurosurgery, and Linton A. Whitaker, M.D. (Lippincott
Williams & Wilkins) This volume examines the relationships among
physical appearance, body image and psychosocial functioning. The authors
detail the psychological implications of specific disfigurements and of
reconstructive procedures, and discuss bioethical, professional and legal
issues.

The Flavor Point Diet: The Delicious, Breakthrough
Plan to Turn Off Your Hunger and Lose the Weight for Good
by David L. Katz, M.D., M.P.H. ’93, associate clinical professor
of public health, and Catherine S. Katz, Ph.D. (Rodale Books) This
book introduces readers to the Flavor Point Diet and provides menu plans
and recipes. By combining foods selected by flavor, the regimen “tricks
the brain into being satisfied all day.”

Globalization, Women, and Health in the 21st
Century
by Ilona S. Kickbusch, Ph.D., former professor of public health, Kari
A. Hartwig, Dr.P.H., assistant clinical professor of public health, and
Justin M. List, M.Div. ’04 (Palgrave Macmillan) This book explores
the complex set of interdependencies among gender, health and globalization.

The Psychotherapist’s Own Psychotherapy: Patient and Clinician
Perspectives
edited by Jesse D. Geller, Ph.D., associate clinical professor of psychiatry,
John C. Norcross, Ph.D., and David E. Orlinsky, Ph.D. (Oxford University
Press) The first-person narratives, clinical wisdom and research findings
gathered in this book offer guidance for providing effective treatments
to patients who are also therapists.

Medical Complications During Pregnancy, 6th ed.
edited by Gerard N. Burrow, M.D. ’58, HS ’66, the David
Paige Smith Professor Emeritus of Medicine and dean emeritus, Thomas P.
Duffy, M.D., professor of medicine (hematology), and Joshua A. Copel,
M.D., FW ’85, professor of obstetrics, gynecology and reproductive
sciences and of pediatrics (W.B. Saunders) This reference book presents
multidisciplinary coverage of the full spectrum of complications associated
with pregnancy. Postpartum depression and bioethics are two of the topics
covered.

Foundations of Anesthesia: Basic Science and Clinical Practice, 2nd
ed.
edited by Hugh C. Hemmings Jr., Ph.D. ’86, M.D. ’87, and
Philip M. Hopkins, M.D. (Elsevier) International experts provide complete
coverage of basic and clinical science in anesthesiology, emphasizing
the principles and clinical applications of molecular and cell biology,
physiology, pharmacology and physics and measurement.

Maimonides
by Sherwin B. Nuland, M.D. ’55, HS ’61 (Schocken Books)
Maimonides was a physician, a Torah scholar, a community leader and a
philosopher who attempted to reconcile scientific knowledge with faith
in God. He was a Jew living in a Muslim world, a rationalist living in
a time of superstition. Nuland gives us a portrait of Maimonides that
makes his life, his times and his thought accessible to the general reader.

Get Hired! How to Land the Ideal Federal Job
and Negotiate a Top Salary
by Lily Whiteman, M.P.H. ’90 (FPMI Solutions) This book,
based on the experiences of people who found federal jobs, provides tips
for breaking into the federal job market—from entry-level to executive
positions. The author provides strategies for finding domestic and overseas
openings, lists the latest federal jobs websites and offers tips for mastering
online applications.

Reconceiving the Gene: Seymour Benzer’s Adventures in Phage Genetics
by the late Frederic L. Holmes, Ph.D., the Avalon Professor of the
History of Medicine and chair of the Section of the History of Medicine,
and edited by William C. Summers, M.D., Ph.D., professor of therapeutic
radiology and of molecular biophysics and biochemistry (Yale University
Press) More than any other individual, biologist Seymour Benzer is
considered to have led geneticists from the classical gene into the molecular
age. Drawing on Benzer’s record of his experiments, correspondence
and published sources, this book reconstructs how the former physicist
initiated his work in phage biology and achieved his landmark investigation.
Nuclear Cardiology, the Basics: How to Set Up
and Maintain a Laboratory
by Frans J.Th. Wackers, M.D., Ph.D., professor of diagnostic radiology
and medicine, Wendy Bruni, and Barry L. Zaret, M.D., the Robert W. Berliner
Professor of Medicine and professor of diagnostic radiology (Humana Press)
This guide offers a concise, action-oriented plan for solving the many
practical and technical problems involved in establishing and running
a nuclear cardiology lab. The authors answer basic questions about purchasing
equipment and determining space requirements.
Rewards for Kids! Ready-to-Use Charts & Activities
for Positive Parenting
by Virginia M. Shiller, Ph.D., lecturer in the Child Study Center,
and Meg F. Schneider (Magination Press) This book shows how to motivate
children to improve their behavior and fulfill their responsibilities,
using a variety of child-friendly sticker charts and other tools. The
authors teach parents positive techniques for helping children to overcome
such common behavior problems as bedtime procrastination and fighting
with siblings.

The descriptions are based on information from the publishers.

Send notices of new books by alumni and faculty to Cheryl Violante, Yale
Medicine, P.O. Box 7612, New Haven, CT 06519-0612, or via e-mail to
cheryl.violante@yale.edu.
In circulation
Consortium seeks to boost minority presence in
health information professions
A senior at Hill Regional Career Magnet High School in New Haven, Jordon
Thomas was impressed when he first set foot in the Cushing/ Whitney Medical
Library last summer. “I didn’t know there were so many resources
that were right in front of me,” said Thomas, who attended a science
program sponsored by the School of Medicine.

Thomas is just the type of student that Charles J. Greenberg, M.L.S.,
M.Ed., coordinator of medical library curriculum and research support,
would like to attract to the health sciences information professions:
a college-bound minority student who might consider becoming a medical
librarian or health information specialist. (As it turns out, Thomas,
who is African-American, plans to be a pharmacist.) Greenberg is the project
coordinator for a newly formed consortium of eight university medical
libraries that is trying to interest minority students in careers in medical
librarianship. Nancy K. Roderer, M.L.S., former director (1992-1999) of
Yale’s medical library and now director of the William H. Welch
Medical Library at Johns Hopkins, is the principal investigator. Funded
with a three-year, $640,000 matching grant from the federal Institute
of Museum and Library Services, the group comprises Yale, Georgetown University,
Houston Academy of Medicine, Howard University, the University of Colorado
at Denver, Johns Hopkins University, the University of Tennessee and Washington
University in St. Louis. Currently, 9 percent of medical librarians are
members of minority groups.

The effort to interest minority students is part of a broader attempt
to recruit health care professionals who reflect the ethnic and racial
diversity of their patients. “Health care providers are very concerned
with cultural competence,” said Greenberg. “We want to become
part of that mosaic of health careers.” The medical librarianship
project is just in the planning stage, but libraries in the group plan
to sponsor tours, internships and other outreach programs.

The group’s task in part is to replace the image of a dowdy
librarian with a more up-to-date view of a computer-savvy “information
specialist.”

Yale’s medical library has been “at the forefront of
the university’s partnerships with the New Haven public schools,”
said Claudia R. Merson, director of public school partnerships at the
Office of New Haven and State Affairs. For instance, Yale medical librarians
taught Internet skills to Career High School teachers and administrators
in the mid-1990s. “This is another opportunity,” said Merson.
“There’s been so much exposure to health professions, but
librarianship has not been one of them. It’s new and exciting, and
it looks like it’s going to be cool.”

The project’s website is http://www.bioinfo-career.org/.

—Cathy Shufro



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On campus

Emergency care in the wake of Katrina
If there was a good news story about Hurricane Katrina, it was the medical
response to the disaster, said Paul K. Carlton Jr., M.D., director
of the Office of Homeland Security of the Texas A&M University System
Health Science Center. Speaking at the Yale New Haven International Congress
on Disaster Medicine and Emergency Management in September, Carlton described
how emergency “surge” hospitals mobilized to handle thousands
of patients in Baton Rouge.

“Your worst nightmare is to lose an entire medical network, and
that is what happened in Katrina,” said Carlton, a proponent of
the surge concept, in which hospitals expand facilities or open new ones
in emergencies. Within days, he said, health and disaster teams had set
up four surge hospitals in Baton Rouge, including one at a former Kmart
store that had been closed for 10 years. “It was filthy,”
Carlton said. Crews found portable air-conditioning units, got power to
the building, bought portable toilets and converted the big-box store
into a 1,000-bed hospital.

Driving the medical teams, Carlton said, was a basic principle: “We
will not break trust with our patients.”

—John Curtis

Bright future for a roller-coaster compound?
In 1998, Endostatin, a protein that inhibits blood vessel growth, was
touted as a silver bullet for cancer after tests in mice showed it killed
tumors by cutting off their blood supply. But six years later, the future
looked bleak: Fortune magazine said the angiogenesis inhibitor
“failed dramatically” in clinical trials, and EntreMed, a
Maryland biotech company, abandoned the drug in 2004 after flirting with
bankruptcy.

But Endostatin is not dead yet, according to its creator, Judah Folkman,
M.D., who spoke at Yale in October. Folkman, a Harvard researcher, said
both reports exaggerated the reality. His work led to FDA approval in
2004 of another angiogenesis drug, Avastin, which is expected to reach
$6 billion in sales and may become the largest-selling anticancer drug
in history.

Three weeks before Folkman’s Yale talk, China approved an Endostatin
product developed and tested by the Chinese biotech company Medgenn. A
trial involving 493 late-stage lung cancer patients showed that its Endostar
drug was effective, doubling survival time from three to six months when
combined with chemotherapy. Folkman hopes the Chinese findings will revive
the future of Endostatin in the American market. “It’s had
a tough life,” he said, “but it’s been resuscitated.”

—Michael Fitzsousa

A pioneering lobotomist’s mixed legacy
When he began his biography of Walter J. Freeman, M.D., a Yale College
graduate who pioneered lobotomy in the United States, journalist Jack
El-Hai expected he would be writing about “a monster.”

The truth was more complicated, said El-Hai, author of The Lobotomist:
A Maverick Medical Genius and His Tragic Quest to Rid the World of Mental
Illness, speaking at a master’s tea at Yale in November. Psychiatrists
embraced the crude surgery that severed neural pathways between the frontal
lobes and the thalamus, El-Hai argued, because until the advent of Thorazine
in 1954 they had few effective treatments for psychiatric illnesses. “They
were willing to try something experimental, something desperate. ... because
at least it held out some hope,” said El-Hai.

From 1936 to 1967 roughly 40,000 patients underwent lobotomies nationwide,
for conditions ranging from depression to schizophrenia. Freeman did 3,400
of them, including one on a sister of John F. Kennedy. Some patients felt
better, some became disabled and 2 percent died.

Freeman, El-Hai noted, “was one of the few advocates of a biological
orientation for psychiatry. That is his most positive legacy today, if
you can find one.”

—Cathy Shufro

NBA star makes a giant impact in his African homeland
As he walked through campus last September, Dikembe Mutombo, all-star
center for the Houston Rockets, cut a somewhat startling figure. With
an impeccably tailored deep-blue suit draped over his 7-foot, 2-inch frame,
Mutombo towered over his hosts like a grade-school teacher minding charges
on a field trip.

He came to Yale at the invitation of Anup Patel, a second-year medical
student who had heard of the Dikembe Mutombo Foundation’s humanitarian
work in Mutombo’s native Democratic Republic of Congo (DRC). Mutombo
contributed $10 million for the construction of a 300-bed hospital in
the capital of Kinshasa, which will open in June to provide care to the
city’s poorest residents and to train its health professionals.
Yale and the foundation are considering a partnership that would provide
opportunities for medical students to travel to the DRC for clinical clerkships.

“I grew up poor and I never forgot where I came from,” said
Mutombo, in an address at Battell Chapel. ”If I was going to do
something that will carry my legacy, I wanted to make sure it was very
good, that it will stop the suffering, that it will help the people that
don’t have a chance to go on a plane to go to South Africa or Europe
to get treatment.”

—Peter Farley
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