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Michael B. Bracken, Ph.D., M.P.H., F.A.C.E

Susan Dwight Bliss Professor of Epidemiology,
Professor, Division of Chronic Disease Epidemiology

Phone: (203) 764-9375
Fax: (203) 764-9378
michael.bracken@yale.edu

Professor Bracken has published over 300 articles and chapters, providing major contributions in the fields of perinatal epidemiolology, clinical trials and evidence–based medicine. His 1984 textbook, Perinatal Epidemiology, defined the field of perinatal epidemiology, predicting the role of fetal and early childhood illness on later chronic disease. Bracken was involved in the discoveries of CFH polymorphism for age–related macular degeneration, the first study to successfully use genome–wide association methodologies and HapMap to identify a disease polymorphism. Professor Bracken is a founder of the evidence–based medicine paradigm. He co–edited one of the first evidence–based texts, Effective Care of the Newborn Infant, forming the basis for the Cochrane Neonatal Review Group. In 2007, the British Medical Journal named the book one of the influential texts in evidence–based medicine.

The first randomized trials for evaluating therapies for acute spinal cord injury were designed and directed by Professor Bracken. He is a consultant for international corporations and government agencies and his government service includes NIH study sections and Council. He presently sits on the NIH Expert Panel on Genes Environment and Health.

Awards and Honors

Wakeman Award for Research in Neuroscience

The Freeman Award

National Rehabilitation Research Award

Research Fellow, Green College, Oxford University

Professional Services

Past President, American College of Epidemiology

Past President, Society for Epidemiologic Research

Chair, first North American Congress of Epidemiology, 2001

Co-chair, first International Colloquium on Genome-Wide Association Studies: Design and Analysis

Current Research Projects
Recent investigations concern identification of genetic polymorphisms that increase disease susceptibility and their interaction with lifestyle risk factors. 

Yale Affiliations

Co-Director, Yale Center for Perinatal, Pediatric and Environmental Epidemiology

Selected Publications

Bracken MB, DeWan A, Hoh J. Genome Wide Association Studies, In Rebbeck TR, Ambrosone CA, Shields, PG (eds). Molecular Epidemiology: Applications in Cancer and Other Human Diseases. New York: Taylor and Francis 2008.

Grosso LM, Triche EW, Benowitz N, Bracken MB. Prenatal Caffeine Assessment: Fetal and Maternal Biomarkers or Self Reported Intake? Annals of Epidemiology 18: 172–178, 2008.

Gork AS, Ehrenkranz RA, Bracken MB. Continuous infusion versus intermittent bolus doses of indomethacin for patent ductus arteriosus closure in symptomatic preterm infants. Cochrane Database of Systematic Reviews 2008.

Triche EW, Grosso LM, Belanger K, Sarefsky AS, Benowitz NL, Bracken MB. Chocolate consumption in pregnancy and reduced likelihood of preeclampsia. Epidemiology 19: 459–464, 2008.

Beckett, W., Gent, J., Naeher, L., Belanger, K., Triche, E., Bracken, M.B., and Leaderer, B. Peak Expiratory Flow Rate Variability is not Affected by Home Combustion Sources in a Group of Non–smoking Women. Archives of Environmental and Occupational Health, 61:176–182, 2007.

Warnick, E.M., Bracken, M.B., and Kasl, S.V. Efficiency of the Child Behavior Checklist and Strengths and Difficulties Questionnaire: A Systematic Review. Child and Adolescent Mental Health, 17: 1–6, 2007.

De Wan, A., Bracken, M.B., and Hoh, J. Two Distinct Genetic Pathways for Age–related Macular Degeneration. Current Opinion in Genetics and Development, 17: 1–6, 2007.

Pettigrew, M.M., Gent, J.F., Zhu, Y., Triche, E.W., Belanger, K., Holford, T.R., Bracken, M.B., and Leaderer, B.P. Respiratory Symptoms among Infants at Risk for Asthma: Association with Surfactant Protein A Haplotypes. BMC Medical Genetics 8: 15, 2007.

For a further list of Dr. Bracken’s publications, please see PubMed.

  Michael B. Bracken photo.

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