Immunobiology / Immunopathology / Vaccine Development

• Principal Investigators

Immunobiology of Normal T Cells

Dr. Philip Askenase's lab is interested in the pathogenesis and regulation of T cell mediated immunity in vivo, as exemplified by contact hypersensitivity. His laboratory found an early initiating phase of these responses (occurring within hours after antigen challenge) and requiring activation of local mast cells and platelets to release mediators, prominently serotonin, as well as transcription of genes and release of cytokines such as TNF-a.
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Immunobiology of Cutaneous T-Cell Lymphoma

For the past twelve years Richard Edelson, Chairman of the Department of Dermatology, has coordinated a broad based research program directed at the elucidation of the basic and clinically relevant properties of cutaneous T cell lymphoma (CTCL) cells. Learn more...

Endothelial Cell: T Cell Interactions

Dario Altieri (Pathology) has two principal research interests:1) leukocyte and endothelial cell interactions with protein cascades in blood coagulation and 2) structure-function characterization of a novel IAP inhibitor of apoptosis, designated survivin. Learn more...

Infectious Diseases/Vaccine Development

YSDRC investigators have been involved in studies of infectious diseases such as Lyme disease, streptococcal infections, papillomavirus infections, Hookworm infections, leishmaniasis and listeriosis. Learn more...