Dermatology
333 Cedar Street, LCI 501
PO Box 208059
New Haven, CT 06520-8059
Tel: 203.785.4091
Fax: 203.785.7637

Assistant Professor of Dermatology,
Director of Dermatology, Yale University Health Services
Director of Dermatology Service, VA Medical Center
Identification of major histocompatibility complex class I (MHC I) associated tumor-specific peptides and immunomodulation of T cell tumors. 2) MHC I antigen processing and presentation in cutaneous T cell lymphoma (CTCL) cells. The research involves isolation, purification and characterization of MHC I self-peptides from a murine and human % cell lymphoma cell lines. Immunoaffinity purification, reversed phase high performance liquid chromatography (RP-HPLC), automated chemical sequencing and peptide synthesis have been used to identify and characterize octamer and nonamer self-peptides from a murine B cell lymphoma cell line. Similar techniques are used to isolate distinctive peptide antigens of CTCL cells and murine T cell tumors. The biological significance of isolated antigens is determined by cytotoxicity assays.
Education: |
BA, Chemistry, Johns Hopkins University, 1984 MD, Albert Einstein College of Medicine, 1988 |
| Training: | Fellowship: Yale School of Medicine |
Academic Office
Yale School of Medicine
333 Cedar Street, LC 501
New Haven, CT 06520-8059
(203) 785-4092
Practice Offices
Yale Dermatology Associates, P.C.
2 Church Street So, Ste 305
New Haven, CT 06519
(203) 789-1249
Yale University Health Services
17 Hillhouse Ave
New Haven, CT 06520
(203) 432-0092
VA Medical Center
950 Campbell Avenue
West Haven, CT 06516
(203) 932-5711 x3118
E-mail
suguru.imaeda@yale.edu