Christina A. Herrick, M.D., Ph.D

Assistant Professor of Dermatology

 

 

Invited Speaker/Lectures

• 2004 Dermatology Grand Rounds at SUNY Downstate Medical Center, Brooklyn, NY; "Systemic Th2 responses and atopic dermatitis: The chicken or the egg?
  
• 2004 Society for Investigative Dermatology Meeting, Providence, RI; Introductory lecture and co-chair of “Inflammation, Autoimmunity and Infection” Minisymposium.
  
• 2004 American Academy of Dermatology Meeting, Washington, DC; "The Immunology of Psoriasis and Atopic Dermatitis" in the Immunology course.
  
• 2003 Dermatology Grand Rounds at Emory School of Medicine, Atlanta, GA; "Th2 responses and atopic skin: The chicken or the egg?"
  
• 2002 Dermatology Grand Rounds at Yale School of Medicine, New Haven, CT; "The rising incidence of atopic disease: Can the hygiene hypothesis explain it all?"
  
• 2002 Society for Investigative Dermatology Meeting, Los Angeles, CA; co-chair of “Inflammation, Autoimmunity and Infection” Minisymposium.
  
• 2002 American Academy of Dermatology Meeting, New Orleans, LA; "The Basics of Cutaneous Immunology" in the Clinical Disease and Its Molecular Basis Course.
  
• 2001 International Symposium on Atopic Dermatitis, Portland, OR; “The Skin as a Sensitization Site for Allergic Airway Responses”.
  
• 2001 American Academy of Dermatology Meeting, Washington, DC; "The Immune System and the Skin: Dysfunction and Disease" in the Clinical Disease and Its Molecular Basis Course.
  
• 2001 Dermatology Alumni Day at SUNY Downstate Medical Center, Brooklyn, NY; "The Immunology of Atopic Dermatitis".

Education:	BA, 1986, Rutgers College, Biology MD/Ph.D., 1993, SUNY - Downstate Medical Center, Brooklyn, NY
Training:	Pathology/Immunology Intern, Yale-New Haven Hospital Internal Medicine Resident, Yale University School of Medicine Dermatology
Professional Associations:	American Academy of Dermatology Society for Investigative Dermatology Dermatology Foundation Women’s Dermatologic Society
Editor/Advisory Boards:	Medical Editor, Dermatology Focus (publication of The Dermatology Foundation), July 2004 - present Member of the Scientific Advisory Board for Novartis Study CASM981CUS09, June 2004 - present
Commitees:	Society for Investigative Dermatology, Committee on Resident/ Fellow Programs 2004-2008 Women's Dermatologic Society, Networking Committee, 2002-2005 Women's Dermatologic Society, Mentorship Award Committee, 1998-2001 The Medical School Council, Yale University School of Medicine, 1996-1997

Selected Publications

• Herrick CA, Smith MC, Wagner K, Heusser C, and Durkin HG. Recombinant interferon gamma-medicated dose dependent regulation of hapten specific IgE anamnestic responses induced in vitro: Lack of effect of recombinant interleukin-4. J Immunol Immunopharmacol X(n): 166, 1990.
• Herrick CA, Carucci JA, Kleiner GI, and Durkin HG. Regulation of hapten-specific memory IgE responses induced in vitro. Requirement for both Thy-1+ AsGM1+ and Thy-1+ AsGM1- cells and for IFN-alpha and Il-4. J Immunol 151: 3440, 1993.
• Carucci JA, Herrick CA, and Durkin HG. Neuropeptide-mediated regulation of hapten-specific IgE responses in mice. II. Mechanisms of substance P-mediated isotype-specific suppression of BPO-specific IgE antibody-forming cell responses induced in vitro. J Neuroimmunol 49: 89, 1994.
• Carucci JA, Auci DL, Herrick CA and Durkin HG. Neuropeptide-mediated regulation of hapten-specific IgE responses in mice. I. Substance P-mediated isotype-specific suppression of BPO-specific IgE antibody-forming cell responses induced in vivo and in vitro. J Leukoc Biol 57:110, 1995.
• Herrick C and Heald P. The Dynamic Interplay of Malignant and Benign T Cells in Cutaneous T-cell Lymphoma. Dermatol Clinics 15: 149, 1997.
• Herrick CA, MacLeod H, Glusac E, Tigelaar RE, Bottomly K. Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4. J Clin Invest, 105:(6), 765-775, 2000
• Wisnewski AV, Srivastava R, Herrick C, Xu L, Lemus R, Cain H, Magoski NM, Karol MH, Bottomly K and Redlich CA. Identification of Human Lung and Skin Proteins Conjugated with Hexamethylene Diisocyanate in Vitro and In Vivo. Am J Respir Crit Care Med 162: 17-7, 2000.
• Cohn, L, C Herrick, N Niu, RJ Homer, and K Bottomly. IL-4 Promotes Airway Eosinophilia by Suppressing IFN-gamma Production: Defining a Novel Role for IFN-gamma in the Regulation of Allergic Airway Inflammation. J Immunol 2001;166: 2760-2767.
• Herrick, CA, L Xu, AV Wisnewski, J Das, CA Redlich, and K Bottomly. A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge. J Allergy Clin Immunol 2002;109:873-878.
• Constant, SL, JL Brogdon, DA Piggott, CA Herrick, I Visintin, NH Ruddle, and K Bottomly. Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ. J Clin Invest 2002;110: 1441-1448.
• Eisenbarth, SC, DA Piggott, JW Huleatt, I Visintin, CA Herrick, and K Bottomly. Lipopolysaccharide-enhanced, Toll-like Receptor 4-dependent T Helper Cell Type 2 Responses to Inhaled Antigen. J Exp Med 2002;196:1-8.
• Herrick, CA, L Xu, ANJ McKenzie, RE Tigelaar, and K Bottomly. IL-13 is necessary, not simply sufficient, for epicutaneously induced Th2 responses to soluble protein antigen. J Immunol 2003;170:2488-95.
• Herrick, CA and K Bottomly. To respond or not to respond: T cells in allergic asthma. Nature Reviews Immunology 2003;3:405-412
• Herrick, CA, J Das, L Xu, AV Wisnewski, CA Redlich, and K Bottomly. Differential roles for CD4 and CD8 T cells following diisocyanate sensitization: Genetic control of Th2-induced lung inflammation. J Allergy Clin Immunol 2003;111:1087-1094.
• Wisnewski, AV, CA Herrick, Q Liu, L Chen, K Bottomly, and C Redlich. Human gamma/delta T cell proliferation and IFN-gamma production induced by hexamethylene diisocyanate. J Allergy Clin Immunol 2003;112:538-546.
• Eisenbarth, SC, A Zhadkevich, P Ranney, CA Herrick, and K Bottomly. IL-4-dependent Th2 collateral priming to inhaled antigens independent of toll-like receptor 4 and myeloid differentiation factor 88. J Immunol. 2004;172:4527-34.
• Piggott DA, SC Eisenbarth, L Xu, SL Constant, JW Huleatt, CA Herrick, and K Bottomly. MyD88-dependent induction of allergic Th2 responses to intranasal antigen. J Clin Invest. 2005;115:459-467.

Chapters

• Herrick CA and Mancewicz M. Basic Science, In Review Notes for the Dermatology Board Exam 1000. Robins P and Kuperman M. Eds. Physicians Continuing Education Corp. New York, NY 2000.
• Herrick, CA and M Mancewicz. Basic Science. In Educational Review Manual in Dermatology, eighth edition. Robins, P and M Perez, Eds. Journal Publishing Group, New York, NY. 2000.
• Herrick, CA and K Watsky. Other Dermatoses. In Textbook of Occupational and Environmental Medicine, 2nd edition, Rosenstock, L, M Cullen, D Brodkin and C Redlich, eds. Harcourt Health Sciences, Philadelphia, PA. 2002.
• Watsky, K and CA Herrick. Contact Dermatitis. In Textbook of Occupational and Environmental Medicine, 2nd edition, Rosenstock, L, M Cullen, D Brodkin and C Redlich, eds. Harcourt Health Sciences, Philadelphia, PA. 2002.

 

Contact

Campus Address
Yale School of Medicine
333 Cedar Street
New Haven, CT 06520-8059

Office Address

E-mail
christina.herrick@yale.edu

Office Phone
(203) 737-1210