Key References

Goshima Y, Nakamura F, Strittmatter P, Strittmatter SM.  Collapsin-induced growth cone collapse mediated by an intracellular protein related to unc-33.  Nature, 376: 509-514  (1995).

Takahashi T, Fournier A, Nakamura F, Wang, LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM.  Plexin-neuropilin1 complexes form functional semaphorin-3A receptors.  Cell 99: 59-69, (1999).

Grandpre T, Nakamura F, Vartanian T, Strittmatter SM.  Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature, 403: 439-444 (2000).

Fournier A, GrandPre T, Strittmatter SM.  Identification of a neuronal receptor mediating Nogo-66 inhibition of axonal regeneration. Nature 409:341-346 (2001).

GrandPre T, Li S, Strittmatter SM. Nogo-66 Receptor Antagonist Peptide Promotes Axonal Regeneration, Nature 417: 547-551 (2002).

Liu B, Fournier A, GrandPre T Strittmatter SM. Myelin-Associated Glycoprotein As A Functional Ligand For The Nogo-66 Receptor.  Science, 297:1190-1193 (2002).

Kim JE, Li S, GrandPré T, Qiu D, Strittmatter SM.  Axon Regeneration in Young Adult Mice Lacking Nogo-A/B. Neuron, 38, 187-199 (2003).

Kim JE, Liu BP. Park JH, Strittmatter SM. Nogo-66 Receptor Prevents Raphespinal and Rubrospinal Axon Regeneration and Limits Functional Recovery from Spinal Cord Injury. Neuron 44:439-451 (2004).

McGee W, Yang Y, Fischer QW, Daw N, Strittmatter SM. Experience-Driven Plasticity Of Visual Cortex Restricted By Myelin And Nogo Receptor.  Science 309: 2222-2226 (2005).

Laurén J, Gimbel DA, Nygaard HB, Gilbert JW, Strittmatter SM. Cellular Prion Protein Mediates Impairment of Synaptic Plasticity by Amyloid-ß Oligomers. Nature 457:1128-1132 (2009).

 

COMPLETE BIBLIOGRAPHY:
Strittmatter SM, Neer EJ.  Properties of separated catalytic and regulatory units of brain adenylate cyclase.  Proc. Natl. Acad. Sci. USA  77:6344-6348 (1980).

Lo MMS, Strittmatter SM, Snyder SH.  Physical separation and reconstitution of two types of benzodiazepine receptors.  Proc. Natl. Acad. Sci. USA  79:680-684 (1982).

Strittmatter SM, Kapiloff MS, Snyder SH.  [3H]Captopril binding to membrane associated angiotensin converting enzyme.  Biochem. Biophys. Res. Commun.   112:1027-1033 (1983).

Strittmatter SM, Lo MMS, Javitch JA, Snyder SH.  Autoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril:  localization to a striatonigral pathway.  Proc. Natl. Acad. Sci. USA   81:1599-1603 (1984).
Strittmatter SM, Snyder SH.  Angiotensin-converting enzyme in the male rat reproductive system:  autoradiographical visualization with [3H]captopril.  Endocrinology  115:2332-2341  (1984).

Kapiloff MS, Strittmatter SM, Fricker LF, Snyder SH.  A fluorometric assay for angiotensin converting enzyme activity.  Analy. Biochem.   140:293-320 (1984).

Lo MMS, Tsong TY, Conrad M, Strittmatter SM, Hester LD, Snyder SH.  Monoclonal antibody production by receptor-mediated electrically induced cell fusion.  Nature  310:792-794  (1984).

Strittmatter SM, Lynch DR, Snyder SH.  [3H]Guanidinoethylmercaptosuccinic acid binding to tissue homogenates:  selective labeling of enkephalin convertase.  J. Biol. Chem.  295:11812-11817  (1984).

Lynch DR, Strittmatter SM, Snyder SH.  Enkephalin convertase localization by [3H]guanidinoethylmercaptosuccinic acid autoradiography:  selective association with enkephalin-containing neurons.  Proc. Natl. Acad. Sci. USA   81:6543-6547  (1984).

Javitch JA, Strittmatter SM, Snyder SH.  Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography.  J. Neurosci.    5:1513-1521  (1985).

Javitch JA, D’Amato RA, Strittmatter SM, Snyder SH.  Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:  uptake of the metobolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.  Proc. Natl. Acad. Sci. USA  82:2173-2177  (1985).

Pevsner J, Trifiletti RR, Strittmatter SM, Snyder SH.  Isolation and characterization of an olfactory receptor for odorant pyrazines.  Proc. Natl. Acad. Sci. USA  82:3050-3054  (1985).

Strittmatter SM, Thiele EA, Kapiloff M, Snyder SH.  A rat brain isozyme of angiotensin converting enzyme:  unique specificity for amidated peptide substrates.  J. Biol. Chem.  260:9825-9832  (1985).

Strittmatter SM, Thiele EA, DeSouza EB, Snyder SH.  Angiotensin-converting enzyme in the testis and epididymis:  differential development and pituitary regulation of isozymes.  Endocrinology  117:1374-1379  (1985).

Strittmatter SM, Lynch DR, De Souza EB, Snyder SH.  Enkephalin convertase visualized in the pituitary and adrenal gland by [3H]guanidinoethylmercaptosuccinic acid (GEMSA) autoradiography:  dehydration decreases neurohypophyseal levels.  Endocrinology   117:1667-1674  (1985).

Thiele EA, Strittmatter SM,  Snyder SH.  Substance K and substance P as possible endogenous substrates of angiotensin converting enzyme in the brain.  Biochem. Biophys. Res. Commun.  128:317-324  (1985).
Lynch DR, Strittmatter SM, Venable JC, Snyder SH.  Enkephalin convertase:  localization to specific neuronal pathways.  J. Neurosci.   6:1662-1675 (1986).

Strittmatter SM, De Souza EB, Lynch DR, Snyder SH.  Angiotensin converting enzyme localized in the rat pituitary and adrenal glands by [3H]captopril autoradiography.  Endocrinology  118:1690-1699  (1986).

Uhl GR, Hackney GO, Tochia M, Stranov V, Tourtellotte WW, Whitehouse PJ, Tran V, Strittmatter S.  Parkinson’s disease:  nigral receptor changes support peptidergic role in nigrostriatal modulation.  Ann. Neurol.   20:194-203 (1986).

Strittmatter SM, Snyder SH.  Characterization of angiotensin converting enzyme by [3H]captopril binding.  Mol. Pharm.  29:142-148 (1986).

Strittmatter SM, Lynch DR, Snyder SH.  Differential ontogeny of rat brain peptidases:  prenatal expression of enkephalin convertase and postnatal development of angiotensin converting enzyme.  Dev. Br. Res.    29:207-215  (1986).

Lynch DR, Strittmatter SM, Venable JC, Snyder SH.  Enkephalin convertase in the gastrointestinal tract and associated organs:  characterization and localization with [3H]guanidinoethylmercaptosuccinic acid.  Endocrinology 121:116-126 (1987).

Strittmatter SM, Snyder SH.  Angiotensin converting enzyme in rat brain and pituitary gland: correlation of isozyme type with cellular localization.  Neuroscience   21:407-420  (1987).

Lynch DR, Venable JC, Strittmatter SM, Snyder SH.  Enkephalin convertase:  characterization and localization using [3H]guanidinoethylmercaptosuccinic acid.  Biochimie    70:57-64 (1988).

Supattapone S, Strittmatter SM, Fricker LD, Snyder SH.  Characterization of a neutral, divalent cation-sensitive endopeptidase:  a possible role in neuropeptide processing.  Brain Res.   417:173-181 (1988).

Strittmatter SM, Braas KM, Snyder SH.  Localization of angiotensin converting enzyme in the ciliary epithelium of the rat eye.  Invest. Ophth. Vis. Sci.   30:2209-2214  (1989).

Zuber MX, Strittmatter SM, Fishman MC.  A growth cone membrane targeting signal in the amino terminus of a neuronal protein.  Nature   341:345-348  (1989).

Strittmatter SM, Valenzuela D, Kennedy TE, Neer EJ, Fishman MC.  Go is a major growth cone membrane component subject to regulation by GAP-43.  Nature   344:836-841  (1990).

Strittmatter SM, Valenzuela, DV, Sudo Y, Linder ME, Fishman MC.  An intracellular guanine nucleotide release protein for Go:  GAP-43 stimulates isolated a subunits by a novel mechanism.  J. Biol. Chem.    266:22465-22471  (1991).

Strittmatter SM, Valenzuela DV, Vartanian T, Sudo Y, Zuber MX, Fishman MC.  Growth cone transduction:  Go and GAP-43.  J. Cell Sci.   Suppl. 15:27-33  (1991).

Strittmatter SM, Fishman MC.  The neuronal growth cone as a specialized transduction system.  BioEssays   13: 117-134  (1991).

Sudo Y, Valenzuela D, Beck-Sickinger AB, Fishman MC and Strittmatter SM.  Palmitoylation alters protein activity: Blockade of Go stimulation by GAP-43.  EMBO J.     11:2095-2102 (1992).

Strittmatter SM, Vartanian T, Fishman MC Plasticity genes in neuronal form and repair.  J. Neurobiol.   23: 507-520  (1992).

Strittmatter SM.  GAP-43 as a modulator of G protein transduction in the growth cone. Perspec. Dev. Neurobiol.     1: 13-19   (1992).

Igarashi M, Strittmatter SM, Vartanian T, Fishman MC. Mediation by G proteins of signals that cause collapse of growth cone.  Science 259: 77-79  (1993).

Cannon SC, Strittmatter SM.  Functional expression of sodium channel mutations identified in families with periodic paralysis.  Neuron   10: 317-326  (1993).

Strittmatter SM, Cannon SC, Ross EM, Higashijima T, Fishman MC.   GAP-43 augments G protein-coupled receptor transduction in X.laevis oocytes. Proc. Natl. Acad. Sci., U.S.A.   90:5327-5331  (1993).

Strittmatter SM, Valenzuela D, Fishman MC.  An amino terminal domain of the growth-associated protein GAP-43 mediates its effects on filopodial formation and cell spreading. J. Cell Sci.  107:195-204  (1994).

Strittmatter SM, Fishman, MC, Zhu XP.  Activated mutants of the a subunit of Go promote an increased number of neurites per cell.  J. Neurosci.   14: 2327-2338  (1994).

Okamoto T, Murayama Y, Strittmatter SM, Katada T, Asano S, Ogata E, Nishimoto I.  An intrinsic guanine nucleotide exchange inhibitor in Gi2 a: significance of G-protein self-suppression which antagonizes receptor signal.  J. Biol. Chem.  269:13756-13759   (1994).

Strittmatter SM, Igarashi M, Fishman MC.  GAP-43 amino terminal peptides modulate growth cone morphology and neurite outgrowth.  J. Neurosci.14: 5503-5513 (1994).

Strittmatter SM, Frankhauser C, Huang PL, Mashimo H, Fishman MC.  Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43.  Cell   80: 445-452  (1995).

Xie R, Li L, Goshima Y, Strittmatter SM.  An activated mutant of the a subunit of Go increases neurite outgrowth via protein kinase C.  Dev. Brain Res.     87: 77-886 (1995).

Goshima Y, Nakamura F, Strittmatter P, Strittmatter SM.  Collapsin-induced growth cone collapse mediated by an intracellular protein related to unc-33.  Nature, 376: 509-514  (1995).

Strittmatter SM.  Neuronal guidance molecules: inhibitory and soluble factors.  The Neuroscientist, 1: 255-258   (1995).
Wang LH, Strittmatter SM.  A family of rat CRMP genes is differentially expressed in the nervous system.    J. Neurosci. 16: 6197-6207  (1996).

Nakamura F, Strittmatter SM.  P2Y1 purinergic receptors in sensory neurons:  contribution to touch-induced impulse generation .  Proc. Natl. Acad. Sci., USA 93: 10465-10470  (1996).

Strittmatter SM.  Signal transduction at the neuronal growth cone.  The Neuroscientist   2:83-86  (1996).

Jin Z, Strittmatter SM.  Rac1 mediates collapsin-induced growth cone collapse.  J. Neurosci., 17: 6256-6263 (1997).

Goshima Y, Kawakami T, Sugiyama Y, Hashimoto Y, Hori H, Kagoshima-Maezono M, Takenaka T, Misu Y, Strittmatter SM.   A novel action of collapsin: Collapsin-1 increases antero- and retrograde axoplasmic transport independently of growth cone collapse.   J. Neurobiology, 33: 316-328 (1997).

Wang LH, Strittmatter SM.  Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase.  J  Neurochem, 69: 2261-2269 (1997). 

Takahashi T, Nakamura F, Strittmatter SM.  Neuronal and non-neuronal collapsin-1 binding sites in developing chick are distinct from other semaphorin binding sites.  J Neurosci, 17: 9183-9193 (1997).

Nakamura F, Takahashi T, Strittmattter SM.  Semaphorins: A family of repulsive factors of neuronal growth cone.  Cell Tech, 16: 1116-1123 (in Japanese) (1997).

Nakamura F,  Strittmatter P, Strittmatter SM. GAP-43 augmentation of G protein-mediated signal transduction is regulated by both phosphorylation and palmitoylation.   J Neurochem, 70: 983-992 (1998).

Takahashi T, Nakamura F, Jin Z, Kalb RG, Strittmatter SM.  Semaphorin A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors.  Nature Neurosci.,  1: 487-493 (1998).

Inglis FM, Furia F, Zuckerman KE, Strittmatter SM, Kalb RG.   The role of nitric oxide and NMDA receptors in the development of motor neuron dendrites. J Neurosci., 18: 10514-10524 (1998).

Nakamura F, Tanaka M, Takahashi T, Kalb RG, Strittmatter SM. Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone  collapse. Neuron, 21: 1093-1100 (1998).

Fryer HL, Knox RJ, Strittmatter SM, Kalb RG.  Excitotxic death of a subset of rat embryonic motor neurons in vitro.  J. Neurochem., 72: 501-513 (1999).

Goshima Y, Hori H, Sasaki Y, Yang T, Kagoshima-Maezono M, Takenaka T, Nakamura F, Takahashi T, Strittmatter, SM, Misu Y, Kawakami T.  Growth cone neuropilin-1 mediates collapsin-1 facilitation of antero-  and retrograde axoplasmic transport.  J. Neurobiol., 39: 579-589 (1999).

Wang LH, Kalb RG, Strittmatter SM. A  PDZ protein  regulates the distribution of the transmembrane semaphorin, M-semF. J. Biol. Chem., 274:14137-14146  (1999).

Yen L, Strittmatter SM, Kalb RG.  Sequence-specific cleavage of Huntingtin mRNA by catalytic DNA. Ann. Neurol., 46: 366-373 (1999).

Takahashi T, Fournier A, Nakamura F, Wang, LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM.  Plexin-neuropilin1 complexes form functional semaphorin-3A receptors.  Cell 99: 59-69, (1999).

Tanaka M, Treloar H, Kalb RG, Greer CA, Strittmatter SM. Go protein-dependent survival of primary accessory olfactory neurons.  Proc. Natl. Acad. Sci., U.S.A., 96: 14106-14111  (1999).

Nakamura F, Goshima Y, Strittmatter SM, Kawamoto S.  Isolation of receptor clones by expression screening in Xenopus oocytes.  Methods in Molecular Biology, 128:1-18, (1999).

Kalb RG, Strittmatter SM (Eds.) “Neurobiology of Spinal Cord Injury”, Totowa, N.J.: Humana Press, Inc. (1999).

Wang LH, Fournier A, Nakamura F, Takahashi T, Kalb RG, Strittmatter SM.  Transduction of inhibitory signals by the axonal growth cone in “Neurobiology of Spinal Cord Injury”, RG Kalb, SM Strittmatter, Eds., Totowa, N.J.: Humana Press, Inc., 131-153  (1999).

Fryer HJ, Wolf DH, Knox RJ, Strittmatter SM, Pennica D, O’Leary RM, Russell DS, Kalb RG.  Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway. J. Neurochem., 74: 582-595 (2000).

Grandpre T, Nakamura F, Vartanian T, Strittmatter SM.  Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature, 403: 439-444 (2000).

Fournier A, Nakamura F, Kawamoto S, Goshima Y, Kalb RG, Strittmatter SM. Semaphorin3A enhances endocytosis at sites of receptor/F-actin colocalization during growth cone collapse.  J Cell Biol. 149: 411-421 (2000).

Nakamura F, Kalb RG, Strittmatter SM. Molecular basis of semaphorin-mediated axonal guidance.  J. Neurobiol. 44: 219-229 (2000).

Fournier A, Kalb RG, Strittmatter SM. Growth cone collapse and Rho GTPases. Meth. Enzymol. 325: 473-482 (2000).
Strittmatter SM. Dendrites go up, axons go down. Nature 404: 557 - 559 (2000).

Fournier A, GrandPre T, Strittmatter SM.  Identification of a neuronal receptor mediating Nogo-66 inhibition of axonal regeneration. Nature 409:341-346 (2001).

Takahashi T, Strittmatter SM. PlexinA1 auto-inhibition by the Plexin sema domain.  Neuron 29: 429-439 (2001).

Fournier A, Strittmatter SM. Repulsive factors and axon regeneration in the CNS. Curr.  Opin. Neurobiol.11:89-94 (2001).

GrandPre T, Strittmatter SM.  Nogo as a molecular determinant of axonal growth and regeneration. The Neuroscientist 7:377-386 (2001).

Liu BP, Strittmatter SM.   Semaphorin-mediated axonal guidance via Rho-related G proteins. Curr. Opin. Cell Biol. 13: 619-626 (2001).

Bonilla IE, Tanabe K, Strittmatter SM. SPRR1A Is Expressed By Axotomized Neurons And Promotes Axonal Outgrowth.  J Neurosci, 22:1303-1315 (2002).

GrandPre T, Li S, Strittmatter SM. Nogo-66 Receptor Antagonist Peptide Promotes Axonal Regeneration, Nature 417: 547-551 (2002).

Wang X, Chun SJ, Treloar H, Vartanian T, Greer CA, Strittmatter SM.  Localization of Nogo-A and Nogo-66 Receptor proteins at sites of axon-myelin and synaptic contact. J. Neurosci., 22: 5505-5515 (2002).

Liu B, Fournier A, GrandPre T Strittmatter SM. Myelin-Associated Glycoprotein As A Functional Ligand For The Nogo-66 Receptor.  Science, 297:1190-1193 (2002).

Fournier AE, Gould GC, Liu BP, Strittmatter SM.  Truncated soluble Nogo Receptor binds Nogo66 and blocks inhibition of axon growth by myelin J. Neurosci., 22:8876-8883 (2002).

Strittmatter SM. Modulation of axonal regeneration in neurodegenerative disease: Focus on Nogo. J. Mol. Neurosci. 19:117-121 (2002).

Fournier AE, Strittmatter SM. Regenerating nerves follow the road more traveled.  Nat Neurosci. 5:821-822 (2002).
Fournier AE, GrandPre T, Gould G, Wang X, Strittmatter SM.  Nogo and the Nogo-66 Receptor. Prog. Brain Res. 137:361-369 (2002).

Fournier AE, Takizawa B, Strittmatter SM.  Rho Kinase Inhibition Promotes Axonal Regeneration in the Injured CNS. J. Neurosci., 23:1416-1423 (2003).

Kim JE, Li S, GrandPré T, Qiu D, Strittmatter SM.  Axon Regeneration in Young Adult Mice Lacking Nogo-A/B. Neuron, 38, 187-199 (2003).

Li S, Strittmatter SM. Delayed Systemic Nogo-66 Receptor Antagonist Promotes Recovery From Spinal Cord Injury.  J. Neurosci., 23: 4219-4227 (2003).

Kim JE, Iris E. Bonilla IE, Qiu D, Strittmatter SM. Nogo-C Is Sufficient To Delay Nerve Regeneration. Mol. Cell. Neurosci. 23:451-459 (2003).

Barton WA, Liu BP, Tzvetkova D,Jeffrey PD, Fournier AE, Sah D, Richard Cate R, Strittmatter SM, Nikolov DB.  Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins.  EMBO J, 22: 3291-3302 (2003).
Tanabe K, Bonilla I, Winkles JA, Strittmatter SM. Fn14 Is Induced In Axotomized Neurons And Promotes Neurite Outgrowth. J Neurosci. 23:9675-9686 (2003).

McGee A, Strittmatter SM. The Nogo-66 receptor: focusing on myelin inhibition of axonal regeneration. Trends in Neruosci., 26:193-8 (2003).

Lee DHS, Strittmatter SM, Sah DWY. Targeting The Nogo Receptor To Treat Central Nervous System Injuries. Nature Rev. Drug Discovery.  2: 1-7 (2003).

Schmidt EF, Togashi H, Strittmatter SM. Semaphorins and their receptors in vertebrates and invertebrates, in  “Handbook of Cell Signaling” RA Bradshaw, E Dennis, Eds., San Diego, CA: Academic Press., 267: 877-881 (2003).

Deo RC, Schmidt EJ, Elhabazi A, Togashi H, Burley SK, Strittmatter SM. Cellular and Structural Bases for CRMP Function In Plexin-Dependent Semaphorin3A Signaling. EMBO J., 23:9-22 (2004).

Acevedo L, Yu J, Erdjument-Bromage H, Miao RQ, Kim JE, Fulton D, Tempst P, Strittmatter SM, Sessa WC. A new role for Nogo as a regulator of vascular remodeling. Nat Med. 10:382-388. (2004).

Weiss J, Takizawa B, McGee A, Stewart  WB, Zhang H, Ment L, Schwartz M, Strittmatter SM.  Neonatal Hypoxia Suppresses Oligodendrocyte Nogo-A And Increases Axonal Sprouting In A Rodent Model For Human Prematurity.  Exp. Neurol. 189:141-149 (2004).

Lee JL, Kim JE, Sivula M, Strittmatter SM. Nogo Receptor Antagonism Promotes Stroke Recovery By Enhancing Axonal Plasticity. J. Neurosci. 24: 6209-6217 (2004).

Rajagopalan S, Deitinghoff L, Davis D,  Conrad S, Skutella T, Chédotal A, Mueller BK, Strittmatter SM. Neogenin Mediates the Action of Repulsive Guidance Molecule. Nature Cell Biol. 6: 756-762 (2004).

Matsunaga E, Tauszig-Delamasure S, Monnier PP, Müeller BK, Strittmatter SM, Mehlen P, Chédotal A. RGM And Its Receptor Neogenin Regulate Neuronal Survival. Nature Cell Biol. 6: 749-755 (2004).

Li W, Walus L, Rabacchi SA, Jirik A, Chang E, Schauer J, Zheng BH, Benedetti NJ, Liu BP, Choi E, Worley D, Silvian L, Mo D, Mullen C, Yang W, Strittmatter SM, Sah DW, Pepinsky B, Lee DH. A neutralizing anti-Nogo66 receptor monoclonal antibody reverses inhibition of neurite outgrowth by central nervous system myelin. J Biol Chem. 279:43780-43788 (2004).

Kim JE, Liu BP. Park JH, Strittmatter SM. Nogo-66 Receptor Prevents Raphespinal and Rubrospinal Axon Regeneration and Limits Functional Recovery from Spinal Cord Injury. Neuron 44:439-451 (2004).

Li S, Liu BP, Budel S, Li M, Ji B, Walus L, Li W, Jirik A, Rabacchi S, Choi E, Worley D, Sah DW, Pepinsky B, Lee D, Relton J, Strittmatter SM.  Blockade of Nogo-66, MAG plus OMgp by Soluble Nogo-66 Receptor Promotes Axonal Sprouting and Recovery after Spinal Injury. J. Neurosci. 24:10511-10520  (2004).

Hu F, Strittmatter SM. Regulating axon growth in the central nervous system. Semin Perinatol. (2004) 28:371-378.
Strittmatter, SM, (Neurology Section Editor) Runge, M., Lewis, C. (Eds.) “Principles of Molecular Medicine”, Totowa, N.J.: Humana Press, Inc. (2006)

Strittmatter, SM,  Axonal regeneration and recovery from chronic CNS injury. In “Principles of Molecular Medicine”, Runge, M., Lewis, C. (Eds.) Totowa, N.J.: Humana Press, Inc. (2006)

Park JH, Strittmatter SM. Promoting the regeneration of axons within the  CNS.  In “Neuroscience, Molecular Medicine and the Therapeutic Transformation of Neurology” Waxman SG (Ed.) Totowa, N.J.: Humana Press, Inc. (2005)

Li S, Kim JE, Budel S, Hampton TG, Strittmatter SM. Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury. Mol Cell Neurosci. 29: 26-39  (2005).

Hu F, Liu BP, Budel S, Liao J, Chin J, Fournier A, Strittmatter SM. Nogo-A Interacts with the Nogo-66 Receptor through Multiple Sites to Create an Isoform-Selective Subnanomolar Agonist. J Neurosci 25:5298-5304 (2005).

 

Ji B, Li M, Budel S, Pepinsky RB, Walus L, Engber TM, Strittmatter SM, Relton JK. Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury. Eur J Neurosci. 22:587-594 (2005).

McGee W, Yang Y, Fischer QW, Daw N, Strittmatter SM. Experience-Driven Plasticity Of Visual Cortex Restricted By Myelin And Nogo Receptor.  Science 309: 2222-2226 (2005).

Marklund N, Fulp CT, Shimizu S, Puri R, McMillan A, Strittmatter SM, McIntosh TK.  Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat. Exp Neurol. 197:70-83 (2006).

Park JH,  Gimbel DA, Li W, GrandPre T, Lee JK, Kim JE, Lee DHS, Strittmatter SM. Alzheimer Precursor Protein Interaction with the Nogo-66 Receptor Reduces Aß Plaque Deposition.  J Neurosci. 26:1386-1395 (2006).

Togashi H, Schmidt EF, Strittmatter SM. RanBPM Mediates Semaphorin3A Signaling through Plexin-A Receptors. J Neurosci 26:4961-4969 (2006).

Liu BP, Cafferty WBJ, Budel SO, Strittmatter SM.  Extracellular Regulators of Axonal Growth in the Adult Central Nervous System.   Philos. Trans. Royal Soc. B: Biol. Sci., 361:1593-1610 (2006).

Miao RQ, Gao Y, Harrison KD, Prendergast J, Acevedo LM, Yu J, Hu F, Strittmatter SM, Sessa WC. Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells.  Proc. Natl. Acad. Sci. USA, 103:10997-11002 (2006).

Harel NY, Strittmatter SM.       Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? Nat Rev Neurosci. 7:603-616 (2006).

Wang X, Baughman KW, Basso DM, Strittmatter SM.  Delayed Nogo Receptor Therapy Improves Recovery of Locomotion after Spinal Cord Contusion.  Ann Neurol., 60:540-549  (2006).

Cafferty WB, Strittmatter SM. The Nogo-Nogo receptor pathway limits a spectrum of adult CNS axonal growth. J Neurosci. 26:12242-12250 (2006).

Park JH, Widi GA, Gimbel DA, Harel NY, Lee DH, Strittmatter SM. Subcutaneous Nogo Receptor Removes Brain Amyloid-{beta} and Improves Spatial Memory in Alzheimer's Transgenic Mice. J Neurosci. 26:13279-13286 (2006).

Laurén J, Hu F, Chin J, Liao J, Airaksinen MS, Strittmatter SM.Characterization of myelin ligand complexes with the neuronal Nogo-66 receptor family. J Biol Chem. 282:5715-5725 (2007).

Cafferty WJ, Yang SH, Duffy P, Li S, Strittmattter SM. Functional Axonal Regeneration Through Astrocytic Scar Genetically Modified to Digest Chondroitin Sulfate Proteoglycans. J Neurosci. 27:2176-2185 (2007).

Harel NY, Strittmatter SM.  Nogo-A marks motor neuron disease. Ann Neurol. 62:1-2 (2007).

Cafferty WB, Kim JE, Lee JK, Strittmatter SM. Response to correspondence: Kim et al., "axon regeneration in young adult mice lacking Nogo-A/B." Neuron 54:195-199 (2007).

Schmandke A, Antonio Schmandke A, Strittmatter SM.  ROCK and Rho: Biochemistry and Neuronal Functions of Rho-Associated Protein Kinases.  The Neuroscientist 13:454-469 (2007).

Park JH, Strittmatter SM. Nogo Receptor Interacts with Brain APP and Aß to Reduce Pathologic Changes in Transgenic Mice. Curr. Alzheimer Res. (2007) 4:568-570.

Schmidt EF, Strittmatter SM.  The CRMP family of proteins and their role in Sema3A signaling. Adv Exp Med Biol. 600:1-11 (2007).

Francks C, Maegawa S, Lauren J, Abrahams BS, Velayos-Baeza A, Medland SE, Colella S, Groszer M, McAuley EZ, Caffrey TM, Timmusk T, Pruunsild P, Koppel I, Lind PA, Matsumoto-Itaba N, Nicod J, Xiong L, Joober R, Enard W, Krinsky B, Nanba E, Richardson AJ, Riley BP, Martin NG, Strittmatter SM, Moller HJ, Rujescu D, St Clair D, Muglia P, Roos JL, Fisher SE, Wade-Martins R, Rouleau GA, Stein JF, Karayiorgou M, Geschwind DH, Ragoussis J, Kendler KS, Airaksinen MS, Oshimura M, Delisi LE, Monaco AP.  LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Mol Psychiatry. 12:1129-1139 (2007)

Cao Y, Shumsky JS, Sabol MA, Kushner RA, Strittmatter SM, Hamers FPT, Lee DHS, Rabacchi SA, Murray M.  Nogo-66 receptor antagonist peptide (NEP1-40) administration promotes functional recovery and axonal growth after lateral funiculus injury in the adult rat. . Neurorehabil Neural Repair. 22:262-278 (2008).

Cameron JS, Alexopoulou L2,4, Jacob A. Sloane JA,  DiBernardo AB, Ma Y,  Kosaras B, Flavell R, Strittmatter SM, Volpe J, Sidman R, Vartanian T. Toll-like receptor 3 is a potent negative regulator of axonal growth in Mammals.  J Neurosci. 27:13033-13041 (2007).

Budel S, Shim SO, Feng Z, Zhao H, Hisama F, Strittmatter SM. No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios. Schizophr Res. 99:365-366 (2008).

Francks C, Maegawa S, Laurén J, Abrahams BS, Velayos-Baeza A, Medland SE, Colella S, Groszer M, McAuley EZ, Caffrey TM, Timmusk T, Pruunsild P, Koppel I, Lind PA, Matsumoto-Itaba N, Nicod J, Xiong L, Joober R, Enard W, Krinsky B, Nanba E, Richardson AJ, Riley BP, Martin NG, Strittmatter SM, Möller HJ, Rujescu D, St Clair D, Muglia P, Roos JL, Fisher SE, Wade-Martins R, Rouleau GA, Stein JF, Karayiorgou M, Geschwind DH, Ragoussis J, Kendler KS, Airaksinen MS, Oshimura M, Delisi LE, Monaco AP.  LRRTM1 protein is located in the endoplasmic reticulum (ER) in mammalian cells. Mol Psychiatry. 12:1057 (2007).

Yang YS, Strittmatter SM. The reticulons: a family of proteins with diverse functions. Genome Biol. 8:234 (2007).
Hu F, Strittmatter SM. The Amino Terminal Domain of Nogo-A Inhibits Cell Adhesion and Axonal Outgrowth by an Integrin-Specific Mechanism.  J Neurosci (2008), 28:1262-1269.

Schmidt E, Shim SO, Strittmatter SM. Release Of MICAL Auto-inhibition By Semaphorin-Plexin Signaling Promotes Interaction With CRMP.  J Neurosci (2008), 28:2287-2297.

Harel NY, Strittmatter SM. Functional MRI and other non-invasive imaging technologies: Providing visual biomarkers for spinal cord structure and function after injury. Exp Neurol. 211:324-328 (2008).

Cafferty WB, McGee AW, Strittmatter SM. Axonal growth therapeutics: regeneration or sprouting or plasticity? Trends Neurosci. 31:215-220 (2008).

Wang XX, Budel S, Baughman K, Gould G, Song KH Strittmatter SM.  Ibuprofen enhances recovery from spinal cord injury by limiting tissue loss and stimulating axonal growth.  J Neurotrauma (2008) in press.

Budel S, Padukkavidana T, Liu BP, Feng Z, Hu F, Johnson S, Lauren J,. Park JH, McGee AW, Liao J, Stillman A, Kim JE, Yang BZ, Stefano Sodi, Joel Gelernter J, Zhao H, Hisama F, Arnsten AFT, Strittmatter SM.   Genetic variants of Nogo-66 Receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci 28:13161-13172 (2008).

Linhoff MW, Laurén J, Cassidy RM, Dobie FA, Takahashi H, Nygaard HB, Airaksinen MS, Strittmatter SM, Craig AM. An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers. Neuron 61:734-749 (2009).

Laurén J, Gimbel DA, Nygaard HB, Gilbert JW, Strittmatter SM. Cellular Prion Protein Mediates Impairment of Synaptic Plasticity by Amyloid-ß Oligomers. Nature 457:1128-1132 (2009).