2PLSM - Two-Photon Laser Scanning Microscope

This two-photon laser scanning mciroscope is an upright Zeiss LSM 510 MP
with a custom-built translation stage and enclosure that is powered by a
Coherent Chameleon Ultra II laser. This system is a dedicated imaging
station for chronic imaging in vivo of the murine nervous system.

Usage:

At present, we are using this equipment to repeatedly image the fine
structure of neurons in the portion of the cerebral cortex that directs
motor coordination, both before and after spinal cord injury (SCI), to
determine how the brain reorganizes following injury. In future
experiments, we will image the injured spinal cord to observe directly
the regrowth of axons from damaged neurons in conjuction with
therapies that promote regeneration and functional recovery from SCI.

Contact:

For questions or to set up a time to use the 2PLSM,
please contact Agnes Ferguson at 737-4311 or
agnes.ferguson@yale.edu

Last modified: Thursday, January 22, 2009 11:16 AM





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