Serguei Bannykh, M.D., Ph.D. Assistant Professor and Attending Neuropathologist Yale University School of Medicine Department of Pathology 310 Cedar Street, BML 122 New Haven, CT 06520 serguei.bannykh@yale.edu

Contact Info

Serguei Bannykh, M.D., Ph.D. 203-785-3624
Fax: 203-785-7037

Research

Serguei Bannykh is an Assistant Professor and Attending Neuropathologist in the Department of Pathology. He specialized in surgical pathology of tumors of central and peripheral nervous system, developmental and neurodegenerative diseases. In particular, he studies a pathogenesis of gliomas and pediatric tumors with neuronal differentiation. Recent work focuses on validation of Sox10 oligodendroglial-specific transcriptional factor as a differential diagnostic marker of oligodendrogliomas. In addition, his research interests include intracellular trafficking of myelin proteins.

Dr. Bannykh completed his training in Anatomic pathology and Neuropathology at the University of California at San Diego. Prior to it his training included a Ph.D. in vascular biology and a postdoctoral training in Cell Biology.

Dr. Bannykh is involved in fundamental and translational research at Yale University School of Medicine.

Education

Selected Peer-reviewed Publications

Bannykh S.I., Rowe T., Balch W.E. Organization of endoplasmic reticulum export complexes. J. Cell Biol.. 1996, 135: 19-35.

Traub, L.M., Bannykh, S.I., Rodel, J.E., Aridor, M., Balch W.E., Kornfeld S. AP-2 containing clathrin coats assemble on mature lysosomes. J. Cell Biol. 1996, 135: 1801-1814.

Rowe T., Dascher C., Bannykh S., Plutner H., Balch W.E. Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates. Science. 1998, 30: 696-70.

Tandon A., Bannykh S., Kowalchyk J.A., Banerjee A., Martin T.F., Balch W.E. Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes. Neuron. 1998, 21:147-54.

Aridor M., Bannykh S.I., Rowe T, Balch W.E. Cargo can modulate COPII vesicle formation from the endoplasmic reticulum. J Biol. Chem. 1999, 274:4389-99.

Nishimura N., Bannykh S., Slabough S., Matteson J., Altschuler Y., Hahn K., Balch W.E . A di-acidic (DXE) code directs concentration of cargo during export from the endoplasmic reticulum. J Biol Chem. 1999, 274: 15937-46.

Bannykh S.I., Bannykh G. I., Fish K. N., Moyer B. D., Riordan J. R., Balch W. E. Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway. Traffic. 2000, 1: 852-870.

Aridor M., Fish K.N., Bannykh S., Weissman J., Roberts T.H., Lippincott-Schwartz J., Balch W.E. The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J Cell Biol. 2001, 152: 213-230.

Yoo JS, Moyer BD, Bannykh S, Yoo HM, Riordan JR, Balch WE. Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway. J Biol Chem. 2002, 277:11401-9.

Phillips P.S., Haas R.H., Bannykh S., Hathaway S., Gray N.L., Kimura B.J., Vladutiu G.D., England J.D. Statin-associated myopathy with normal creatine kinase levels. Ann. Intern. Med. 2002; 137: 581-5.

Bannykh S.I. Balch W.E. Membrane dynamics at the endoplasmic reticulum-Golgi interface. J. Cell Biol. 1997, 138: 1-4.

Bannykh S.I., Balch W.E. Selective transport of cargo between the endoplasmic reticulum and Golgi compartments. Histochem. Cell Biol. 1998, 109:463-75.

Bannykh S.I., Nishimura N., Balch W.E. Getting into the Golgi. Trends Cell Biol. 1998, 8:21-5