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W. Mark Saltzman

 

Physiology & Integrative Medical Biology; Neuroscience

Goizueta Foundation Professor of Chemical and Biomedical Engineering

Chair, Biomedical Engineering

Professor of Cellular & Molecular Physiology

Education

B.S. Iowa State University 1981
Ph.D. Massachusetts Institute of Technology 1987

Research Interests

We are studying the use of novel drug delivery systems, which are based primarily on biocompatible polymers. Our current studies focus on three different clinical applications of these materials: 1) for local delivery of potent agents such as chemotherapy in tumors or paracrine growth factors in tissue repair; 2) for enhancing the delivery and/or presentation of antigens to the immune system for vaccination; and 3) for non-viral DNA expression in cells and tissues.

Links

• Saltzman Homepage

Recent Publications

• Shen, H., Hu, Y.Y., and Saltzman, W.M. (2006). DNA diffusion in mucus: effect of size, topology and charge of DNAs. Biophysical J. 91:639-644.
• Neeves, K.B., Lo, C.T., Foley, C.P., Saltzman, W.M., and Olbricht, W.L. (2006). Fabrication and characterization of microfluidic probes for convection enhanced drug delivery. J. Controlled Release 111:252-262.

Contact

E-mail
mark.saltzman@yale.edu