Yale University

Biological and Biomedical Sciences

Biological and Biomedical Sciences, Yale School of Medicine

BBS Program
Yale University
P.O. Box 208084
New Haven, CT 06520-8084
Tel: 203.785.3735
Fax: 203.785.3734
bbs@yale.edu

James Mazer

 

Neuroscience

Assistant Professor of Neurobiology

Education

B.A. Yale College 1987
Ph.D. California Institute of Technology 1995

Research Interests

Neuroscientists have identified more than 30 distinct cortical and sub-cortical areas in the primate brain that contribute to visual processing. However, we really only understand the specific contributions a small number of the areas make to visual perception. In my laboratory we use a combination of neurophysiological, psychophysical, and computational methods to study the contributions of occipital and parietal cortex to visual perception and action. We use nonlinear system identification techniques to analyze both single neuron responses in extrastriate cortex and psychophysical performance data from subjects performing attentionally demanding visual search tasks. These data are used to construct visual selectivity profiles for both single neurons and individual subjects.  By using similar methods to study both single neurons and perception we can accurately estimate the contributions of single neurons to perception and action. The primary focus of this research is characterizing the effects of top-down modulatory signals on visual perception and to determine how the visual system influences the oculomotor system to guide eye movements during natural visual exploration of the world around us.

Links

Recent Publications

  • Wang, M., et al. (2007). Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129(2):397-410.
  • Mazer, J.A. and Gallant, J.L. (2003). Goal-related activity in V4 during free viewing visual search: Evidence for a ventral stream visual salience map. Neuron 4(6):1241-50.

James Mazer

Contact

E-mail
james.mazer@yale.edu