Yale University

Biological and Biomedical Sciences

Biological and Biomedical Sciences, Yale School of Medicine

BBS Program
Yale University
P.O. Box 208084
New Haven, CT 06520-8084
Tel: 203.785.3735
Fax: 203.785.3734
bbs@yale.edu

R. Todd Constable

 

Molecular Cell Biology, Genetics & Development

Professor of Diagnostic Radiology, Neurosurgery, and Biomedical Engineering

Education

B.Sc. University of Winnipeg 1984
Ph.D. University of Toronto 1990

Research Interests

My research is focused on developing and validating novel approaches to functional Magnetic Resonance Imaging (fMRI) and using these methods to improve our understanding of brain function. This work includes approaches for quantitative neuroimaging and methods for assessing brain function via connectivity mapping. These developments are applied in the neurosurgical environment to localizing epileptogenic tissue and mapping function prior to surgical intervention. These studies provide a framework for validating the fMRI techniques through comparisons with cortical stimulation, behavioral analyses, Wada testing, and patient outcomes. They also improve our understanding of the link between fMRI signal changes and neuronal activity, through comparisons of fMRI in vivo with EEG?/?ERP recordings obtained in patients with depth electrodes and/or subdural grids. We are also interested in better understanding basic language and memory processing in humans and factors that influence the networks revealed by neuroimaging.

Links

Recent Publications

  • Hampson, M., Driesen, N.R., Skudlarski, P., Gore, J.C., and Constable, R.T. (2006). Brain connectivity related to working memory performance. J. Neurosci. 26(51):13338-13343.
  • Hampson, M., Tokoglu, F., Sun, Z., Schafer, R.J., Gore, J.C., and Constable, R.T. (2006). Connectivity-behavior analysis reveals functional connectivity between left BA39 and Broca?fs area varies with reading ability. Neuroimage 31(2):513-519.

R. Todd Constable

Contact

E-mail
todd.constable@yale.edu